sulforaphane has been researched along with Astrocytoma, Grade IV in 11 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here we uncovered the involved subcellular mechanisms that sulforaphane-cysteine (SFN-Cys) inhibited invasion in human glioblastoma (GBM)." | 7.96 | Sulforaphane-cysteine inhibited migration and invasion via enhancing mitophagosome fusion to lysosome in human glioblastoma cells. ( Hu, Y; Li, J; Wang, Y; Wu, S; Wu, W; Yan, Y; Zheng, Z; Zhou, Y, 2020) |
| "We previously demonstrated that sulforaphane (SFN) inhibited invasion via sustained activation of ERK1/2 in human glioblastoma cells." | 7.85 | Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells. ( Geng, Y; Hu, Y; Lin, K; Tian, H; Wu, S; Wu, W; Yang, G; Zhou, Y, 2017) |
| "The survival benefits of patients with glioblastoma (GBM) remain unsatisfactory due to the intrinsic or acquired resistance to temozolomide (TMZ)." | 7.83 | Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression. ( Han, J; Lan, F; Wu, Q; Yang, Y; Yu, H; Yue, X, 2016) |
| "Temozolomide (TMZ) has been widely used in the treatment of glioblastoma (GBM), although inherent or acquired resistance restricts the application." | 7.81 | Sulforaphane enhances temozolomide-induced apoptosis because of down-regulation of miR-21 via Wnt/β-catenin signaling in glioblastoma. ( Lan, F; Pan, Q; Yu, H; Yue, X, 2015) |
| "Sulforaphane (SFN) was demonstrated to inhibit cell growth in a variety of tumors." | 5.40 | Sulforaphane inhibits invasion via activating ERK1/2 signaling in human glioblastoma U87MG and U373MG cells. ( Du, L; Li, C; Niu, J; Peng, X; Tian, H; Wu, W; Yang, G; Zhou, Y, 2014) |
| "Here we uncovered the involved subcellular mechanisms that sulforaphane-cysteine (SFN-Cys) inhibited invasion in human glioblastoma (GBM)." | 3.96 | Sulforaphane-cysteine inhibited migration and invasion via enhancing mitophagosome fusion to lysosome in human glioblastoma cells. ( Hu, Y; Li, J; Wang, Y; Wu, S; Wu, W; Yan, Y; Zheng, Z; Zhou, Y, 2020) |
| "We previously demonstrated that sulforaphane (SFN) inhibited invasion via sustained activation of ERK1/2 in human glioblastoma cells." | 3.85 | Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells. ( Geng, Y; Hu, Y; Lin, K; Tian, H; Wu, S; Wu, W; Yang, G; Zhou, Y, 2017) |
| "The survival benefits of patients with glioblastoma (GBM) remain unsatisfactory due to the intrinsic or acquired resistance to temozolomide (TMZ)." | 3.83 | Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression. ( Han, J; Lan, F; Wu, Q; Yang, Y; Yu, H; Yue, X, 2016) |
| "Temozolomide (TMZ) has been widely used in the treatment of glioblastoma (GBM), although inherent or acquired resistance restricts the application." | 3.81 | Sulforaphane enhances temozolomide-induced apoptosis because of down-regulation of miR-21 via Wnt/β-catenin signaling in glioblastoma. ( Lan, F; Pan, Q; Yu, H; Yue, X, 2015) |
| "Glioblastoma is the most common primary tumor of the brain and has few long-term survivors." | 1.46 | Modulating glioma-mediated myeloid-derived suppressor cell development with sulforaphane. ( Daniels, DJ; de Mooij, T; Johnson, AJ; Kaptzan, T; Kumar, R; Parney, IF; Peterson, TE, 2017) |
| "Sulforaphane (SFN) was demonstrated to inhibit cell growth in a variety of tumors." | 1.40 | Sulforaphane inhibits invasion via activating ERK1/2 signaling in human glioblastoma U87MG and U373MG cells. ( Du, L; Li, C; Niu, J; Peng, X; Tian, H; Wu, W; Yang, G; Zhou, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (72.73) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Sita, G | 2 |
| Graziosi, A | 2 |
| Hrelia, P | 2 |
| Morroni, F | 2 |
| Gasparello, J | 1 |
| Papi, C | 1 |
| Zurlo, M | 1 |
| Gambari, L | 1 |
| Rozzi, A | 1 |
| Manicardi, A | 1 |
| Corradini, R | 1 |
| Gambari, R | 1 |
| Finotti, A | 1 |
| Zhou, Y | 3 |
| Wang, Y | 1 |
| Wu, S | 2 |
| Yan, Y | 1 |
| Hu, Y | 2 |
| Zheng, Z | 1 |
| Li, J | 1 |
| Wu, W | 3 |
| Yang, G | 2 |
| Tian, H | 2 |
| Geng, Y | 1 |
| Lin, K | 1 |
| Kumar, R | 1 |
| de Mooij, T | 1 |
| Peterson, TE | 1 |
| Kaptzan, T | 1 |
| Johnson, AJ | 1 |
| Daniels, DJ | 1 |
| Parney, IF | 1 |
| Li, C | 1 |
| Peng, X | 1 |
| Du, L | 1 |
| Niu, J | 1 |
| Lan, F | 2 |
| Pan, Q | 1 |
| Yu, H | 2 |
| Yue, X | 2 |
| Yang, Y | 1 |
| Han, J | 1 |
| Wu, Q | 1 |
| Miao, Z | 1 |
| Yu, F | 1 |
| Ren, Y | 1 |
| Yang, J | 1 |
| Bijangi-Vishehsaraei, K | 1 |
| Reza Saadatzadeh, M | 1 |
| Wang, H | 1 |
| Nguyen, A | 1 |
| Kamocka, MM | 1 |
| Cai, W | 1 |
| Cohen-Gadol, AA | 1 |
| Halum, SL | 1 |
| Sarkaria, JN | 1 |
| Pollok, KE | 1 |
| Safa, AR | 1 |
1 review available for sulforaphane and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Sulforaphane from Cruciferous Vegetables: Recent Advances to Improve Glioblastoma Treatment.
Topics: Antineoplastic Agents, Phytogenic; Brassica; Glioblastoma; Humans; Isothiocyanates; Sulfoxides; Vege | 2018 |
10 other studies available for sulforaphane and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Sulforaphane Causes Cell Cycle Arrest and Apoptosis in Human Glioblastoma U87MG and U373MG Cell Lines under Hypoxic Conditions.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tu | 2021 |
Treatment of Human Glioblastoma U251 Cells with Sulforaphane and a Peptide Nucleic Acid (PNA) Targeting miR-15b-5p: Synergistic Effects on Induction of Apoptosis.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Drug Synergism; Gene Expression Regulation, Neoplastic; | 2022 |
Sulforaphane-cysteine inhibited migration and invasion via enhancing mitophagosome fusion to lysosome in human glioblastoma cells.
Topics: Cell Line, Tumor; Cell Movement; Cysteine; Glioblastoma; Humans; Isothiocyanates; Lysosomes; Neoplas | 2020 |
Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells.
Topics: Apoptosis; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine | 2017 |
Modulating glioma-mediated myeloid-derived suppressor cell development with sulforaphane.
Topics: Brain Neoplasms; CD11b Antigen; Cell Hypoxia; Cell Line, Tumor; Culture Media, Conditioned; Fucosylt | 2017 |
Sulforaphane inhibits invasion via activating ERK1/2 signaling in human glioblastoma U87MG and U373MG cells.
Topics: Anticarcinogenic Agents; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Res | 2014 |
Sulforaphane enhances temozolomide-induced apoptosis because of down-regulation of miR-21 via Wnt/β-catenin signaling in glioblastoma.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, | 2015 |
Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression.
Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Modifica | 2016 |
d,l-Sulforaphane Induces ROS-Dependent Apoptosis in Human Gliomablastoma Cells by Inactivating STAT3 Signaling Pathway.
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Isothiocy | 2017 |
Sulforaphane suppresses the growth of glioblastoma cells, glioblastoma stem cell-like spheroids, and tumor xenografts through multiple cell signaling pathways.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; DNA Damage; Glioblasto | 2017 |