sulforaphane has been researched along with Asthma, Bronchial in 6 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty-five moderate asthmatics were administered sulforaphane (100 μmol daily for 14 days), BP, BD, lung volumes by body-plethsmography, and airway morphology by computed tomography (CT) were measured pre- and post sulforaphane consumption." | 9.20 | Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways. ( Brooker, A; Brown, RH; Fahey, JW; Reynolds, C; Talalay, P, 2015) |
| " In this study, we attempt to determine whether sulforaphane regulates the inflammatory response in an ovalbumin (OVA)-induced murine asthma model." | 7.78 | Sulforaphane inhibits the Th2 immune response in ovalbumin-induced asthma. ( Chung, SW; Heo, DR; Jung, ID; Kim, JW; Kim, YD; Lee, CM; Noh, KT; Park, JH; Park, JW; Park, YM; Seo, JK; Shin, YK, 2012) |
| "Sulforaphane treatment led to induction of antioxidant enzymes (SOD, GPx) in AECs and pulmonary non-enzymatic antioxidants." | 5.51 | Sulforaphane treatment reverses corticosteroid resistance in a mixed granulocytic mouse model of asthma by upregulation of antioxidants and attenuation of Th17 immune responses in the airways. ( Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Alqahtani, F; Alqinyah, M; AlThagfan, SS; Ibrahim, KE; Nadeem, A, 2019) |
| "Forty-five moderate asthmatics were administered sulforaphane (100 μmol daily for 14 days), BP, BD, lung volumes by body-plethsmography, and airway morphology by computed tomography (CT) were measured pre- and post sulforaphane consumption." | 5.20 | Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways. ( Brooker, A; Brown, RH; Fahey, JW; Reynolds, C; Talalay, P, 2015) |
| "The ovalbumin-induced (OVA) chronic allergic airways murine model is a well-established model for investigating pre-clinical therapies for chronic allergic airways diseases, such as asthma." | 3.96 | Investigation of molecular mechanisms of experimental compounds in murine models of chronic allergic airways disease using synchrotron Fourier-transform infrared microspectroscopy. ( Bambery, KR; Karagiannis, TC; Licciardi, PV; Mazarakis, N; Royce, SG; Samuel, CS; Snibson, KJ; Tobin, MJ; Ververis, K; Vongsvivut, J, 2020) |
| " In this study, we attempt to determine whether sulforaphane regulates the inflammatory response in an ovalbumin (OVA)-induced murine asthma model." | 3.78 | Sulforaphane inhibits the Th2 immune response in ovalbumin-induced asthma. ( Chung, SW; Heo, DR; Jung, ID; Kim, JW; Kim, YD; Lee, CM; Noh, KT; Park, JH; Park, JW; Park, YM; Seo, JK; Shin, YK, 2012) |
| "Sulforaphane treatment led to induction of antioxidant enzymes (SOD, GPx) in AECs and pulmonary non-enzymatic antioxidants." | 1.51 | Sulforaphane treatment reverses corticosteroid resistance in a mixed granulocytic mouse model of asthma by upregulation of antioxidants and attenuation of Th17 immune responses in the airways. ( Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Alqahtani, F; Alqinyah, M; AlThagfan, SS; Ibrahim, KE; Nadeem, A, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Mazarakis, N | 1 |
| Vongsvivut, J | 1 |
| Bambery, KR | 1 |
| Ververis, K | 1 |
| Tobin, MJ | 1 |
| Royce, SG | 1 |
| Samuel, CS | 1 |
| Snibson, KJ | 1 |
| Licciardi, PV | 1 |
| Karagiannis, TC | 1 |
| Sakurai, H | 1 |
| Morishima, Y | 1 |
| Ishii, Y | 1 |
| Yoshida, K | 1 |
| Nakajima, M | 1 |
| Tsunoda, Y | 1 |
| Hayashi, SY | 1 |
| Kiwamoto, T | 1 |
| Matsuno, Y | 1 |
| Kawaguchi, M | 1 |
| Yamamoto, M | 1 |
| Hizawa, N | 1 |
| Al-Harbi, NO | 1 |
| Nadeem, A | 1 |
| Ahmad, SF | 1 |
| AlThagfan, SS | 1 |
| Alqinyah, M | 1 |
| Alqahtani, F | 1 |
| Ibrahim, KE | 1 |
| Al-Harbi, MM | 1 |
| Brown, RH | 1 |
| Reynolds, C | 1 |
| Brooker, A | 1 |
| Talalay, P | 1 |
| Fahey, JW | 1 |
| Michaeloudes, C | 1 |
| Chang, PJ | 1 |
| Petrou, M | 1 |
| Chung, KF | 1 |
| Park, JH | 1 |
| Kim, JW | 1 |
| Lee, CM | 1 |
| Kim, YD | 1 |
| Chung, SW | 1 |
| Jung, ID | 1 |
| Noh, KT | 1 |
| Park, JW | 1 |
| Heo, DR | 1 |
| Shin, YK | 1 |
| Seo, JK | 1 |
| Park, YM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluating the Role of Oxidant/Anti-oxidant Balance and the Relationship of Asthma Severity on Airway Smooth Muscle Proliferation, Migration and Cytokine Release.[NCT00779870] | 18 participants (Actual) | Observational | 2008-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Expression of Nrf2 protein (NCT00779870)
Timeframe: at time of bronchoscopy, an average of 1 hour
| Intervention | relative expression unit (Mean) |
|---|---|
| Healthy | 2 |
| Non-severe Asthma | 3 |
| Severe Asthma | 3 |
1 trial available for sulforaphane and Asthma, Bronchial
| Article | Year |
|---|---|
Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways.
Topics: Adult; Airway Resistance; Antioxidants; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tes | 2015 |
5 other studies available for sulforaphane and Asthma, Bronchial
| Article | Year |
|---|---|
Investigation of molecular mechanisms of experimental compounds in murine models of chronic allergic airways disease using synchrotron Fourier-transform infrared microspectroscopy.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Chronic Disease; Disease Models, Animal; Drug Evaluation, Pr | 2020 |
Sulforaphane ameliorates steroid insensitivity through an Nrf2-dependent pathway in cigarette smoke-exposed asthmatic mice.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Dexamethasone; Disease Models, Animal; Drug Combinations; Fe | 2018 |
Sulforaphane treatment reverses corticosteroid resistance in a mixed granulocytic mouse model of asthma by upregulation of antioxidants and attenuation of Th17 immune responses in the airways.
Topics: Adrenal Cortex Hormones; Animals; Antioxidants; Asthma; Cytokines; Disease Models, Animal; Drug Resi | 2019 |
Transforming growth factor-β and nuclear factor E2–related factor 2 regulate antioxidant responses in airway smooth muscle cells: role in asthma.
Topics: Adenoviridae; Antioxidants; Asthma; Cell Proliferation; Gene Expression; Gene Expression Regulation; | 2011 |
Sulforaphane inhibits the Th2 immune response in ovalbumin-induced asthma.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dow | 2012 |