sulforaphane has been researched along with Arthritis, Rheumatoid in 5 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was performed to define the effects of sulforaphane on interleukin-1β (IL-1β)-induced proliferation of rheumatoid arthritis synovial fibroblasts (RASFs), the expression of matrix metalloproteinases (MMPs) and cyclooxygenase (COX), and the production of prostaglandin E2 (PGE2) by RASFs." | 7.80 | Sulforaphane inhibits IL-1β-induced proliferation of rheumatoid arthritis synovial fibroblasts and the production of MMPs, COX-2, and PGE2. ( Choi, YJ; Lee, EG; Lee, WS; Sung, MS; Yoo, WH, 2014) |
| "To investigate whether sulforaphane (SFN), an isothiocyanate derived from cruciferous vegetables such as broccoli, regulates synoviocyte hyperplasia and T cell activation in rheumatoid arthritis (RA)." | 7.76 | Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate. ( Cho, CS; Chung, YJ; Kim, HA; Kim, HS; Kim, WU; Kong, JS; Ryu, SH; Yea, K; Yoo, SA, 2010) |
| "Sulforaphane (SFN) is a natural compound that has been suggested as an antioxidant." | 5.48 | Sulforaphane Modulates Joint Inflammation in a Murine Model of Complete Freund's Adjuvant-Induced Mono-Arthritis. ( Abreu-Silva, AL; da Penha, TA; de Aquino, AF; de Sá, JC; de Souza, BGGF; Fialho Sousa, NC; França Muniz, T; Grisotto, MAG; Nascimento da Silva, LC; Neuza da Silva Nina, L; Silva E Silva, C; Silva Rodrigues, JF; Soares Fernandes, E, 2018) |
| "This study was performed to define the effects of sulforaphane on interleukin-1β (IL-1β)-induced proliferation of rheumatoid arthritis synovial fibroblasts (RASFs), the expression of matrix metalloproteinases (MMPs) and cyclooxygenase (COX), and the production of prostaglandin E2 (PGE2) by RASFs." | 3.80 | Sulforaphane inhibits IL-1β-induced proliferation of rheumatoid arthritis synovial fibroblasts and the production of MMPs, COX-2, and PGE2. ( Choi, YJ; Lee, EG; Lee, WS; Sung, MS; Yoo, WH, 2014) |
| "To investigate whether sulforaphane (SFN), an isothiocyanate derived from cruciferous vegetables such as broccoli, regulates synoviocyte hyperplasia and T cell activation in rheumatoid arthritis (RA)." | 3.76 | Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate. ( Cho, CS; Chung, YJ; Kim, HA; Kim, HS; Kim, WU; Kong, JS; Ryu, SH; Yea, K; Yoo, SA, 2010) |
| "Sulforaphane treatment reduced the arthritis score and the severity of histologic inflammation in CIA mice." | 1.62 | The anti-arthritis effect of sulforaphane, an activator of Nrf2, is associated with inhibition of both B cell differentiation and the production of inflammatory cytokines. ( Cho, ML; Jhun, J; Jung, K; Kim, SY; Kwon, JY; Min, JK; Moon, SJ; Ryu, J, 2021) |
| "Sulforaphane (SFN) is a natural compound that has been suggested as an antioxidant." | 1.48 | Sulforaphane Modulates Joint Inflammation in a Murine Model of Complete Freund's Adjuvant-Induced Mono-Arthritis. ( Abreu-Silva, AL; da Penha, TA; de Aquino, AF; de Sá, JC; de Souza, BGGF; Fialho Sousa, NC; França Muniz, T; Grisotto, MAG; Nascimento da Silva, LC; Neuza da Silva Nina, L; Silva E Silva, C; Silva Rodrigues, JF; Soares Fernandes, E, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, Y | 1 |
| Li, HY | 1 |
| Li, XH | 1 |
| Lu, J | 1 |
| Zhang, Q | 1 |
| Bai, CG | 1 |
| Chen, Y | 1 |
| Moon, SJ | 1 |
| Jhun, J | 1 |
| Ryu, J | 1 |
| Kwon, JY | 1 |
| Kim, SY | 1 |
| Jung, K | 1 |
| Cho, ML | 1 |
| Min, JK | 1 |
| Silva Rodrigues, JF | 1 |
| Silva E Silva, C | 1 |
| França Muniz, T | 1 |
| de Aquino, AF | 1 |
| Neuza da Silva Nina, L | 1 |
| Fialho Sousa, NC | 1 |
| Nascimento da Silva, LC | 1 |
| de Souza, BGGF | 1 |
| da Penha, TA | 1 |
| Abreu-Silva, AL | 1 |
| de Sá, JC | 1 |
| Soares Fernandes, E | 1 |
| Grisotto, MAG | 1 |
| Choi, YJ | 1 |
| Lee, WS | 1 |
| Lee, EG | 1 |
| Sung, MS | 1 |
| Yoo, WH | 1 |
| Kong, JS | 1 |
| Yoo, SA | 1 |
| Kim, HS | 1 |
| Kim, HA | 1 |
| Yea, K | 1 |
| Ryu, SH | 1 |
| Chung, YJ | 1 |
| Cho, CS | 1 |
| Kim, WU | 1 |
5 other studies available for sulforaphane and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Therapeutic effects of isothiocyanate prodrugs on rheumatoid arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Body Weight; Half-Life; Iso | 2018 |
The anti-arthritis effect of sulforaphane, an activator of Nrf2, is associated with inhibition of both B cell differentiation and the production of inflammatory cytokines.
Topics: Animals; Arthritis, Rheumatoid; B-Lymphocytes; Cell Differentiation; Cytokines; Inflammation; Isothi | 2021 |
Sulforaphane Modulates Joint Inflammation in a Murine Model of Complete Freund's Adjuvant-Induced Mono-Arthritis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Biomarkers; Cytokines; Disease Models, Anim | 2018 |
Sulforaphane inhibits IL-1β-induced proliferation of rheumatoid arthritis synovial fibroblasts and the production of MMPs, COX-2, and PGE2.
Topics: Arthritis, Rheumatoid; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Fibrobla | 2014 |
Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate.
Topics: Animals; Antirheumatic Agents; Apoptosis; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Survi | 2010 |