sulforaphane has been researched along with Allergic Reaction in 2 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulforaphane has been investigated in human pathologies and preclinical models of airway diseases." | 1.72 | Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant, and epigenetic mechanisms. ( Beh, RC; Bourke, JE; Donovan, C; El-Osta, A; Hung, A; Karagiannis, TC; Khurana, I; Liang, JJ; Licciardi, PV; Maxwell, S; Mazarakis, N; Pitsillou, E; Royce, SG; Samuel, CS; Siow, YY; Snibson, KJ; Tang, MLK; Tobin, MJ; Ververis, K; Vongsvivut, J; Ziemann, M, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Royce, SG | 1 |
| Licciardi, PV | 1 |
| Beh, RC | 1 |
| Bourke, JE | 1 |
| Donovan, C | 1 |
| Hung, A | 1 |
| Khurana, I | 1 |
| Liang, JJ | 1 |
| Maxwell, S | 1 |
| Mazarakis, N | 1 |
| Pitsillou, E | 1 |
| Siow, YY | 1 |
| Snibson, KJ | 1 |
| Tobin, MJ | 1 |
| Ververis, K | 1 |
| Vongsvivut, J | 1 |
| Ziemann, M | 1 |
| Samuel, CS | 1 |
| Tang, MLK | 1 |
| El-Osta, A | 1 |
| Karagiannis, TC | 1 |
| Heber, D | 1 |
| Li, Z | 1 |
| Garcia-Lloret, M | 1 |
| Wong, AM | 1 |
| Lee, TY | 1 |
| Thames, G | 1 |
| Krak, M | 1 |
| Zhang, Y | 1 |
| Nel, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Broccoli Sprout Extract Effects on the Inflammatory Response to Diesel Exhaust Particles in the Nose[NCT00882115] | 38 participants (Actual) | Interventional | 2009-07-10 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change of total nasal cell count in response to a standard diesel exhaust particle (DEP) challenge was determined by counting the total number of cells (leukocytes) recovered from nasal lavage fluid at 0 hr (just prior to DEP dosing), 6 hr and 24 hr later in participants who consuming BSE for 4 days, or without consuming BSE (control). Nasal challenges were performed with 300 microgram a standard DEP in 200 microliter saline. (NCT00882115)
Timeframe: 0, 6 and 24 hours at Control visit and BSE visit (Day 4 of intervention)
| Intervention | log cells/mL (Mean) | |||||
|---|---|---|---|---|---|---|
| 0 hr prior DEP dosing (control) | 6 hr after DEP dosing (control) | 24 hr after DEP dosing (control) | 0 hr prior to DEP doising with BSE intervention | 6 hr after DEP dosing with BSE intervention | 24 hr after DEP dosing with BSE intervention | |
| Nasal DEP Challenge | 4.44 | 4.50 | 4.73 | 4.70 | 4.44 | 4.57 |
1 trial available for sulforaphane and Allergic Reaction
| Article | Year |
|---|---|
Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles.
Topics: Adult; Air Pollutants; Brassica; Female; Humans; Hypersensitivity; Isothiocyanates; Male; NF-E2-Rela | 2014 |
1 other study available for sulforaphane and Allergic Reaction
| Article | Year |
|---|---|
Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant, and epigenetic mechanisms.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Epigenesis, Genetic; Humans; Hypersensitivity; Leuk | 2022 |