sulforaphane has been researched along with Aging in 14 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although SFN was broadly chemoprotective within an hormetic dose-response context, it also enhanced cell proliferation/cell viability at low concentrations in multiple tumor cell lines." | 2.72 | The phytoprotective agent sulforaphane prevents inflammatory degenerative diseases and age-related pathologies via Nrf2-mediated hormesis. ( Calabrese, EJ; Kozumbo, WJ, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 12 (85.71) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, H | 2 |
| Zhou, L | 2 |
| Davies, KJA | 2 |
| Forman, HJ | 2 |
| Calabrese, EJ | 1 |
| Kozumbo, WJ | 1 |
| Kubo, E | 1 |
| Chhunchha, B | 1 |
| Singh, P | 1 |
| Sasaki, H | 1 |
| Singh, DP | 1 |
| Santín-Márquez, R | 1 |
| Alarcón-Aguilar, A | 1 |
| López-Diazguerrero, NE | 1 |
| Chondrogianni, N | 1 |
| Königsberg, M | 1 |
| Saleh, DO | 1 |
| Mansour, DF | 1 |
| Hashad, IM | 1 |
| Bakeer, RM | 1 |
| Martin, SL | 1 |
| Hardy, TM | 1 |
| Tollefsbol, TO | 1 |
| Malaguti, M | 1 |
| Angeloni, C | 1 |
| Hrelia, S | 1 |
| Townsend, BE | 1 |
| Johnson, RW | 1 |
| Pal, S | 1 |
| Konkimalla, VB | 1 |
| Zanichelli, F | 1 |
| Capasso, S | 1 |
| Cipollaro, M | 1 |
| Pagnotta, E | 1 |
| Cartenì, M | 1 |
| Casale, F | 1 |
| Iori, R | 1 |
| Galderisi, U | 1 |
| Wang, N | 1 |
| Wang, Y | 1 |
| Yu, G | 1 |
| Yuan, C | 1 |
| Ma, J | 1 |
| Chapple, SJ | 1 |
| Siow, RC | 1 |
| Mann, GE | 1 |
| Kim, HJ | 1 |
| Barajas, B | 1 |
| Wang, M | 1 |
| Nel, AE | 1 |
7 reviews available for sulforaphane and Aging
| Article | Year |
|---|---|
Silencing Bach1 alters aging-related changes in the expression of Nrf2-regulated genes in primary human bronchial epithelial cells.
Topics: Adult; Aged; Aging; Basic-Leucine Zipper Transcription Factors; Bronchi; Epithelial Cells; Gene Expr | 2019 |
The phytoprotective agent sulforaphane prevents inflammatory degenerative diseases and age-related pathologies via Nrf2-mediated hormesis.
Topics: Aging; Animals; Anti-Inflammatory Agents; Hormesis; Humans; Isothiocyanates; Neuroprotective Agents; | 2021 |
Sulforaphane - role in aging and neurodegeneration.
Topics: Aging; Animals; Antioxidants; Epigenesis, Genetic; Humans; Inflammation; Isothiocyanates; Kelch-Like | 2019 |
Medicinal chemistry of the epigenetic diet and caloric restriction.
Topics: Aging; Anticarcinogenic Agents; Caloric Restriction; Catechin; Chemistry, Pharmaceutical; Curcumin; | 2013 |
Nutraceutical Bioactive Compounds Promote Healthspan Counteracting Cardiovascular Diseases.
Topics: Aged; Aged, 80 and over; Aging; Anticarcinogenic Agents; Antioxidants; Cardiovascular Diseases; Diet | 2015 |
Hormetic Potential of Sulforaphane (SFN) in Switching Cells' Fate Towards Survival or Death.
Topics: Aging; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic | 2016 |
Crosstalk between Nrf2 and the proteasome: therapeutic potential of Nrf2 inducers in vascular disease and aging.
Topics: Aging; Animals; Gene Expression; Humans; Isothiocyanates; Models, Biological; NF-E2-Related Factor 2 | 2012 |
7 other studies available for sulforaphane and Aging
| Article | Year |
|---|---|
Aging-related decline in the induction of Nrf2-regulated antioxidant genes in human bronchial epithelial cells.
Topics: Adult; Aged; Aging; Antioxidants; Basic-Leucine Zipper Transcription Factors; Bronchi; Cells, Cultur | 2018 |
Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress.
Topics: Active Transport, Cell Nucleus; Adolescent; Adult; Aged; Aging; Animals; Antioxidants; Cell Nucleus; | 2017 |
Effects of sulforaphane on D-galactose-induced liver aging in rats: Role of keap-1/nrf-2 pathway.
Topics: Aging; Animals; Antioxidants; Biomarkers; Galactose; Heme Oxygenase (Decyclizing); Isothiocyanates; | 2019 |
Sulforaphane induces Nrf2 target genes and attenuates inflammatory gene expression in microglia from brain of young adult and aged mice.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cytokines; DNA-Binding Pro | 2016 |
Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect.
Topics: Aging; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Cycle Checkpoints; Ce | 2012 |
Quinoprotein adducts accumulate in the substantia nigra of aged rats and correlate with dopamine-induced toxicity in SH-SY5Y cells.
Topics: Aging; Animals; Cysteine; Dopamine; Dopamine Antagonists; Dopaminergic Neurons; Humans; Hydroquinone | 2011 |
Nrf2 activation by sulforaphane restores the age-related decrease of T(H)1 immunity: role of dendritic cells.
Topics: Acetylcysteine; Adoptive Transfer; Aging; Animals; Dendritic Cells; Dermatitis, Contact; Female; Flo | 2008 |