Page last updated: 2024-11-04

sulforaphane and Acute Lung Injury

sulforaphane has been researched along with Acute Lung Injury in 5 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).

Research Excerpts

ExcerptRelevanceReference
"Sulforaphane (SFN) is a phytochemical antioxidant known to affect multiple cellular targets including Nrf2-ARE pathway in chemoprevention."1.51Sulforaphane enriched transcriptome of lung mitochondrial energy metabolism and provided pulmonary injury protection via Nrf2 in mice. ( Bell, DA; Blankenship-Paris, T; Cho, HY; Deterding, L; Kleeberger, SR; Lih, F; Miller-DeGraff, L; Morgan, DL; Panduri, V; Reddy, AJ; Talalay, P; Wang, X; Yamamoto, M, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Zhang, L1
Xu, L1
Chen, H1
Zhang, W1
Xing, C1
Qu, Z1
Yu, J1
Zhuang, C1
Liang, W1
Greven, J1
Fragoulis, A1
Horst, K1
Bläsius, F1
Wruck, C1
Pufe, T1
Kobbe, P1
Hildebrand, F1
Lichte, P1
Cho, HY1
Miller-DeGraff, L1
Blankenship-Paris, T1
Wang, X1
Bell, DA1
Lih, F1
Deterding, L1
Panduri, V1
Morgan, DL1
Yamamoto, M1
Reddy, AJ1
Talalay, P1
Kleeberger, SR1
Qi, T1
Xu, F1
Yan, X1
Li, S1
Li, H1
Jensen, JS1
Fan, X1
Guidot, DM1

Other Studies

5 other studies available for sulforaphane and Acute Lung Injury

ArticleYear
Structure-based molecular hybridization design of Keap1-Nrf2 inhibitors as novel protective agents of acute lung injury.
    European journal of medicinal chemistry, 2021, Oct-15, Volume: 222

    Topics: Acute Lung Injury; Animals; Dose-Response Relationship, Drug; Drug Design; Female; Kelch-Like ECH-As

2021
Sulforaphane-Dependent Up-Regulation of NRF2 Activity Alleviates Both Systemic Inflammatory Response and Lung Injury After Hemorrhagic Shock/Resuscitation in Mice.
    Shock (Augusta, Ga.), 2022, 02-01, Volume: 57, Issue:2

    Topics: Acute Lung Injury; Animals; Isothiocyanates; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-E2-Rela

2022
Sulforaphane enriched transcriptome of lung mitochondrial energy metabolism and provided pulmonary injury protection via Nrf2 in mice.
    Toxicology and applied pharmacology, 2019, 02-01, Volume: 364

    Topics: Acute Lung Injury; Animals; Antioxidant Response Elements; Antioxidants; Disease Models, Animal; DNA

2019
Sulforaphane exerts anti-inflammatory effects against lipopolysaccharide-induced acute lung injury in mice through the Nrf2/ARE pathway.
    International journal of molecular medicine, 2016, Volume: 37, Issue:1

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidant Response Elements; Interleukin-6;

2016
Alcohol causes alveolar epithelial oxidative stress by inhibiting the nuclear factor (erythroid-derived 2)-like 2-antioxidant response element signaling pathway.
    American journal of respiratory cell and molecular biology, 2013, Volume: 48, Issue:4

    Topics: Acute Lung Injury; Alcohol Drinking; Animals; Anticarcinogenic Agents; Blood-Air Barrier; Cell Line;

2013