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sulforaphane and Acute Liver Injury, Drug-Induced

sulforaphane has been researched along with Acute Liver Injury, Drug-Induced in 9 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Research Excerpts

ExcerptRelevanceReference
" This study aimed to investigate the protective potential of sulforaphane (SF), nuclear factor E2 related factor (Nrf-2) activator, against CPZ-induced cardiotoxicity and hepatotoxicity."8.31Sulforaphane, an Nrf-2 Agonist, Modulates Oxidative Stress and Inflammation in a Rat Model of Cuprizone-Induced Cardiotoxicity and Hepatotoxicity. ( Ibrahim Fouad, G, 2023)
"The aim of the present study was to reveal the possible effect of sulforaphane on oxidative stress and inflammation in rats liver with toxic hepatitis induced by acetaminophene."7.85The effect of sulforaphane on oxidative stress and inflammation in rats with toxic hepatitis induced by acetaminophene. ( Aktas, MS; Dokumacioglu, A; Dokumacioglu, E; Hanedan, B; Iskender, H; Musmul, A; Sen, TM, 2017)
" This study aimed to investigate the protective potential of sulforaphane (SF), nuclear factor E2 related factor (Nrf-2) activator, against CPZ-induced cardiotoxicity and hepatotoxicity."4.31Sulforaphane, an Nrf-2 Agonist, Modulates Oxidative Stress and Inflammation in a Rat Model of Cuprizone-Induced Cardiotoxicity and Hepatotoxicity. ( Ibrahim Fouad, G, 2023)
"The aim of the present study was to reveal the possible effect of sulforaphane on oxidative stress and inflammation in rats liver with toxic hepatitis induced by acetaminophene."3.85The effect of sulforaphane on oxidative stress and inflammation in rats with toxic hepatitis induced by acetaminophene. ( Aktas, MS; Dokumacioglu, A; Dokumacioglu, E; Hanedan, B; Iskender, H; Musmul, A; Sen, TM, 2017)
"Sulforaphane (SFN) is a thiol compound found in wide abundance in cruciferous plants that has numerous reported therapeutic efficacies."1.46Sulforaphane protects against sodium valproate-induced acute liver injury. ( Atef, H; El-Khouly, OA; Nazmy, EA; Said, E, 2017)
" The results showed that triptolide caused oxidative stress and cell damage in HepG2 cells, and these toxic effects could be aggravated by Nrf2 knockdown or be counteracted by overexpression of Nrf2."1.40Activation of Nrf2 protects against triptolide-induced hepatotoxicity. ( Fu, X; Guan, C; Huang, M; Huang, Z; Jin, J; Li, J; Shen, F; Sun, X; Wang, W, 2014)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (77.78)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Ibrahim Fouad, G1
Isaacson, RH1
Beier, JI1
Khoo, NK1
Freeman, BA1
Freyberg, Z1
Arteel, GE1
Dokumacioglu, E1
Iskender, H1
Aktas, MS1
Hanedan, B1
Dokumacioglu, A1
Sen, TM1
Musmul, A1
Copple, IM1
den Hollander, W1
Callegaro, G1
Mutter, FE1
Maggs, JL1
Schofield, AL1
Rainbow, L1
Fang, Y1
Sutherland, JJ1
Ellis, EC1
Ingelman-Sundberg, M1
Fenwick, SW1
Goldring, CE1
van de Water, B1
Stevens, JL1
Park, BK1
Thangapandiyan, S1
Ramesh, M1
Hema, T1
Miltonprabu, S1
Uddin, MS1
Nandhini, V1
Bavithra Jothi, G1
Li, J1
Shen, F1
Guan, C1
Wang, W1
Sun, X1
Fu, X1
Huang, M1
Jin, J1
Huang, Z1
Noh, JR1
Kim, YH1
Hwang, JH1
Choi, DH1
Kim, KS1
Oh, WK1
Lee, CH1
Nazmy, EA1
El-Khouly, OA1
Atef, H1
Said, E1
Gaona-Gaona, L1
Molina-Jijón, E1
Tapia, E1
Zazueta, C1
Hernández-Pando, R1
Calderón-Oliver, M1
Zarco-Márquez, G1
Pinzón, E1
Pedraza-Chaverri, J1

Other Studies

9 other studies available for sulforaphane and Acute Liver Injury, Drug-Induced

ArticleYear
Sulforaphane, an Nrf-2 Agonist, Modulates Oxidative Stress and Inflammation in a Rat Model of Cuprizone-Induced Cardiotoxicity and Hepatotoxicity.
    Cardiovascular toxicology, 2023, Volume: 23, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotoxicity; Catalase; Chemical and Drug Induced

2023
Olanzapine-induced liver injury in mice: aggravation by high-fat diet and protection with sulforaphane.
    The Journal of nutritional biochemistry, 2020, Volume: 81

    Topics: Animals; Antioxidants; Antipsychotic Agents; Body Weight; Chemical and Drug Induced Liver Injury; Di

2020
The effect of sulforaphane on oxidative stress and inflammation in rats with toxic hepatitis induced by acetaminophene.
    Bratislavske lekarske listy, 2017, Volume: 118, Issue:8

    Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants; Aspartate Amin

2017
Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury.
    Archives of toxicology, 2019, Volume: 93, Issue:2

    Topics: Cells, Cultured; Chemical and Drug Induced Liver Injury; Gene Expression Regulation; Gene Regulatory

2019
Sulforaphane Potentially Ameliorates Arsenic Induced Hepatotoxicity in Albino Wistar Rats: Implication of PI3K/Akt/Nrf2 Signaling Pathway.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2019, Volume: 52, Issue:5

    Topics: Animals; Arsenic; Chemical and Drug Induced Liver Injury; Isothiocyanates; Liver; Male; NF-E2-Relate

2019
Activation of Nrf2 protects against triptolide-induced hepatotoxicity.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Chemical and Drug Induced Liver

2014
Sulforaphane protects against acetaminophen-induced hepatotoxicity.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2015, Volume: 80

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anticarcinogenic Agents; Cells, Cultured; Chemical

2015
Sulforaphane protects against sodium valproate-induced acute liver injury.
    Canadian journal of physiology and pharmacology, 2017, Volume: 95, Issue:4

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Anticonvulsants; A

2017
Protective effect of sulforaphane pretreatment against cisplatin-induced liver and mitochondrial oxidant damage in rats.
    Toxicology, 2011, Aug-15, Volume: 286, Issue:1-3

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Antioxidants; Chemical and Drug Induced Liv

2011
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