sulforaphane and Acute Liver Injury, Drug-Induced
sulforaphane has been researched along with Acute Liver Injury, Drug-Induced in 9 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study aimed to investigate the protective potential of sulforaphane (SF), nuclear factor E2 related factor (Nrf-2) activator, against CPZ-induced cardiotoxicity and hepatotoxicity." | 8.31 | Sulforaphane, an Nrf-2 Agonist, Modulates Oxidative Stress and Inflammation in a Rat Model of Cuprizone-Induced Cardiotoxicity and Hepatotoxicity. ( Ibrahim Fouad, G, 2023) |
| "The aim of the present study was to reveal the possible effect of sulforaphane on oxidative stress and inflammation in rats liver with toxic hepatitis induced by acetaminophene." | 7.85 | The effect of sulforaphane on oxidative stress and inflammation in rats with toxic hepatitis induced by acetaminophene. ( Aktas, MS; Dokumacioglu, A; Dokumacioglu, E; Hanedan, B; Iskender, H; Musmul, A; Sen, TM, 2017) |
| " This study aimed to investigate the protective potential of sulforaphane (SF), nuclear factor E2 related factor (Nrf-2) activator, against CPZ-induced cardiotoxicity and hepatotoxicity." | 4.31 | Sulforaphane, an Nrf-2 Agonist, Modulates Oxidative Stress and Inflammation in a Rat Model of Cuprizone-Induced Cardiotoxicity and Hepatotoxicity. ( Ibrahim Fouad, G, 2023) |
| "The aim of the present study was to reveal the possible effect of sulforaphane on oxidative stress and inflammation in rats liver with toxic hepatitis induced by acetaminophene." | 3.85 | The effect of sulforaphane on oxidative stress and inflammation in rats with toxic hepatitis induced by acetaminophene. ( Aktas, MS; Dokumacioglu, A; Dokumacioglu, E; Hanedan, B; Iskender, H; Musmul, A; Sen, TM, 2017) |
| "Sulforaphane (SFN) is a thiol compound found in wide abundance in cruciferous plants that has numerous reported therapeutic efficacies." | 1.46 | Sulforaphane protects against sodium valproate-induced acute liver injury. ( Atef, H; El-Khouly, OA; Nazmy, EA; Said, E, 2017) |
| " The results showed that triptolide caused oxidative stress and cell damage in HepG2 cells, and these toxic effects could be aggravated by Nrf2 knockdown or be counteracted by overexpression of Nrf2." | 1.40 | Activation of Nrf2 protects against triptolide-induced hepatotoxicity. ( Fu, X; Guan, C; Huang, M; Huang, Z; Jin, J; Li, J; Shen, F; Sun, X; Wang, W, 2014) |
Research
Studies (9)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Ibrahim Fouad, G | 1 |
| Isaacson, RH | 1 |
| Beier, JI | 1 |
| Khoo, NK | 1 |
| Freeman, BA | 1 |
| Freyberg, Z | 1 |
| Arteel, GE | 1 |
| Dokumacioglu, E | 1 |
| Iskender, H | 1 |
| Aktas, MS | 1 |
| Hanedan, B | 1 |
| Dokumacioglu, A | 1 |
| Sen, TM | 1 |
| Musmul, A | 1 |
| Copple, IM | 1 |
| den Hollander, W | 1 |
| Callegaro, G | 1 |
| Mutter, FE | 1 |
| Maggs, JL | 1 |
| Schofield, AL | 1 |
| Rainbow, L | 1 |
| Fang, Y | 1 |
| Sutherland, JJ | 1 |
| Ellis, EC | 1 |
| Ingelman-Sundberg, M | 1 |
| Fenwick, SW | 1 |
| Goldring, CE | 1 |
| van de Water, B | 1 |
| Stevens, JL | 1 |
| Park, BK | 1 |
| Thangapandiyan, S | 1 |
| Ramesh, M | 1 |
| Hema, T | 1 |
| Miltonprabu, S | 1 |
| Uddin, MS | 1 |
| Nandhini, V | 1 |
| Bavithra Jothi, G | 1 |
| Li, J | 1 |
| Shen, F | 1 |
| Guan, C | 1 |
| Wang, W | 1 |
| Sun, X | 1 |
| Fu, X | 1 |
| Huang, M | 1 |
| Jin, J | 1 |
| Huang, Z | 1 |
| Noh, JR | 1 |
| Kim, YH | 1 |
| Hwang, JH | 1 |
| Choi, DH | 1 |
| Kim, KS | 1 |
| Oh, WK | 1 |
| Lee, CH | 1 |
| Nazmy, EA | 1 |
| El-Khouly, OA | 1 |
| Atef, H | 1 |
| Said, E | 1 |
| Gaona-Gaona, L | 1 |
| Molina-Jijón, E | 1 |
| Tapia, E | 1 |
| Zazueta, C | 1 |
| Hernández-Pando, R | 1 |
| Calderón-Oliver, M | 1 |
| Zarco-Márquez, G | 1 |
| Pinzón, E | 1 |
| Pedraza-Chaverri, J | 1 |
Other Studies
9 other studies available for sulforaphane and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Sulforaphane, an Nrf-2 Agonist, Modulates Oxidative Stress and Inflammation in a Rat Model of Cuprizone-Induced Cardiotoxicity and Hepatotoxicity.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotoxicity; Catalase; Chemical and Drug Induced | 2023 |
Olanzapine-induced liver injury in mice: aggravation by high-fat diet and protection with sulforaphane.
Topics: Animals; Antioxidants; Antipsychotic Agents; Body Weight; Chemical and Drug Induced Liver Injury; Di | 2020 |
The effect of sulforaphane on oxidative stress and inflammation in rats with toxic hepatitis induced by acetaminophene.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants; Aspartate Amin | 2017 |
Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury.
Topics: Cells, Cultured; Chemical and Drug Induced Liver Injury; Gene Expression Regulation; Gene Regulatory | 2019 |
Sulforaphane Potentially Ameliorates Arsenic Induced Hepatotoxicity in Albino Wistar Rats: Implication of PI3K/Akt/Nrf2 Signaling Pathway.
Topics: Animals; Arsenic; Chemical and Drug Induced Liver Injury; Isothiocyanates; Liver; Male; NF-E2-Relate | 2019 |
Activation of Nrf2 protects against triptolide-induced hepatotoxicity.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Chemical and Drug Induced Liver | 2014 |
Sulforaphane protects against acetaminophen-induced hepatotoxicity.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anticarcinogenic Agents; Cells, Cultured; Chemical | 2015 |
Sulforaphane protects against sodium valproate-induced acute liver injury.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Anticonvulsants; A | 2017 |
Protective effect of sulforaphane pretreatment against cisplatin-induced liver and mitochondrial oxidant damage in rats.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Antioxidants; Chemical and Drug Induced Liv | 2011 |