Page last updated: 2024-11-04

sulfobromophthalein and Hepatolenticular Degeneration

sulfobromophthalein has been researched along with Hepatolenticular Degeneration in 4 studies

Sulfobromophthalein: A phenolphthalein that is used as a diagnostic aid in hepatic function determination.

Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.

Research Excerpts

ExcerptRelevanceReference
"Wilson's disease is an inherited, autosomal recessive disorder of copper accumulation and toxicity."1.34Down-regulation of intestinal multidrug resistance-associated protein 2 in long-evans cinnamon rats. ( Chiba, M; Hirano, T; Iseki, K; Itagaki, S; Kobayashi, M, 2007)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Itagaki, S2
Sugawara, M1
Kobayashi, M2
Miyazaki, K1
Hirano, T2
Iseki, K2
Chiba, M1
Colón, AR1
Sandberg, DH1
Schoenfield, LJ1
Onstad, GR1
Goldstein, NP1

Reviews

1 review available for sulfobromophthalein and Hepatolenticular Degeneration

ArticleYear
Presently recognized forms of inherited jaundice in infancy. A summary and review.
    Clinical pediatrics, 1973, Volume: 12, Issue:6

    Topics: Bilirubin; Biological Transport; Cholestasis; Diagnosis, Differential; Feces; Galactosemias; Hepatit

1973

Other Studies

3 other studies available for sulfobromophthalein and Hepatolenticular Degeneration

ArticleYear
Comparison of the disposition behavior of organic anions in an animal model for Wilson's disease (Long-Evans Cinnamon rats) with that in normal Long-Evans Agouti rats.
    Drug metabolism and pharmacokinetics, 2004, Volume: 19, Issue:2

    Topics: Animals; Anions; Area Under Curve; Bile; Chromatography, High Pressure Liquid; Hepatolenticular Dege

2004
Down-regulation of intestinal multidrug resistance-associated protein 2 in long-evans cinnamon rats.
    Drug metabolism and pharmacokinetics, 2007, Volume: 22, Issue:6

    Topics: Animals; ATP-Binding Cassette Transporters; Disease Models, Animal; Down-Regulation; Hepatolenticula

2007
Normal sulfobromophthalein retention in established liver disease.
    The American journal of digestive diseases, 1970, Volume: 15, Issue:4

    Topics: Bile; Biliary Tract; Biological Transport; False Negative Reactions; Hemochromatosis; Hepatolenticul

1970
chemdatabank.com