sulfobromophthalein and Hepatolenticular Degeneration
sulfobromophthalein has been researched along with Hepatolenticular Degeneration in 4 studies
Sulfobromophthalein: A phenolphthalein that is used as a diagnostic aid in hepatic function determination.
Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Wilson's disease is an inherited, autosomal recessive disorder of copper accumulation and toxicity." | 1.34 | Down-regulation of intestinal multidrug resistance-associated protein 2 in long-evans cinnamon rats. ( Chiba, M; Hirano, T; Iseki, K; Itagaki, S; Kobayashi, M, 2007) |
Research
Studies (4)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Itagaki, S | 2 |
Sugawara, M | 1 |
Kobayashi, M | 2 |
Miyazaki, K | 1 |
Hirano, T | 2 |
Iseki, K | 2 |
Chiba, M | 1 |
Colón, AR | 1 |
Sandberg, DH | 1 |
Schoenfield, LJ | 1 |
Onstad, GR | 1 |
Goldstein, NP | 1 |
Reviews
1 review available for sulfobromophthalein and Hepatolenticular Degeneration
Article | Year |
---|---|
Presently recognized forms of inherited jaundice in infancy. A summary and review.
Topics: Bilirubin; Biological Transport; Cholestasis; Diagnosis, Differential; Feces; Galactosemias; Hepatit | 1973 |
Other Studies
3 other studies available for sulfobromophthalein and Hepatolenticular Degeneration
Article | Year |
---|---|
Comparison of the disposition behavior of organic anions in an animal model for Wilson's disease (Long-Evans Cinnamon rats) with that in normal Long-Evans Agouti rats.
Topics: Animals; Anions; Area Under Curve; Bile; Chromatography, High Pressure Liquid; Hepatolenticular Dege | 2004 |
Down-regulation of intestinal multidrug resistance-associated protein 2 in long-evans cinnamon rats.
Topics: Animals; ATP-Binding Cassette Transporters; Disease Models, Animal; Down-Regulation; Hepatolenticula | 2007 |
Normal sulfobromophthalein retention in established liver disease.
Topics: Bile; Biliary Tract; Biological Transport; False Negative Reactions; Hemochromatosis; Hepatolenticul | 1970 |