sulfobromophthalein has been researched along with Constitutional Liver Dysfunction in 24 studies
Sulfobromophthalein: A phenolphthalein that is used as a diagnostic aid in hepatic function determination.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although in Gilbert's syndrome (GS), bilirubin glucuronidation is impaired due to an extra TA in the TATA box of the promoter of the gene for bilirubin UDP-glucuronosyltransferase 1 (UGT1A1), many GS homozygotes lack unconjugated hyperbilirubinemia." | 3.71 | Hepatic uptake of organic anions affects the plasma bilirubin level in subjects with Gilbert's syndrome mutations in UGT1A1. ( Amoroso, A; Bakker, CT; Bosma, PJ; Ostrow, JD; Persico, E; Persico, M; Rigato, I; Tiribelli, C; Torella, R, 2001) |
| "Gilbert's syndrome is typically associated with a deficiency in hepatic bilirubin UDP-glucuronosyltransferase activity (B-GTA)." | 2.36 | New insights into the classification and mechanisms of hereditary, chronic, non-haemolytic hyperbilirubinaemias. ( Berthelot, P; Dhumeaux, D, 1978) |
| "Future studies of Gilbert's syndrome must take into account the existence of these subgroups, since they may have different underlying pathogenetic mechanisms." | 2.35 | Abnormal hepatic transport of indocyanine green in Gilbert's syndrome. ( Berk, PD; Martin, JF; Scharschmidt, BF; Vergalla, J; Vierling, JM; Waggoner, JG; Wolkoff, AW, 1976) |
| "It is concluded that in Gilbert's syndrome two weeks of treatment with cimetidine had no effect on liver blood flow or on conjugation mechanisms which were independent of cytochrome P450." | 1.27 | Effect of cimetidine on the metabolism of cholephilic dyes in Gilbert's syndrome. ( Deres, M; Kutz, K, 1984) |
| "The recognition that Gilbert's syndrome is a quite heterogeneous entity will allow a better understanding of the mode of inheritance of this disorder; its relationship to Crigler-Najjar type II disease also awaits further definition." | 1.27 | Familial unconjugated hyperbilirubinemia syndromes. ( Reichen, J, 1983) |
| "were investigated in 51 subjects with Gilbert's syndrome and 35 control subjects of both sexes." | 1.27 | The implication of bilitranslocase function in the impaired rifamycin SV metabolism in Gilbert's syndrome. ( Baldini, G; Gentile, S; Lunazzi, G; Persico, M; Sottocasa, GL; Tiribelli, C, 1985) |
| "The 13 patients with Gilbert's syndrome could be divided into three groups according to their BSP disappearance curves: in 7 the curves were normal; another 3 patients the disappearance rate of BSP was normal at the beginning, but became abnormally low later on; and in the last 3 patients, an abnormal BSP disappearance rate was observed during the whole experiment." | 1.27 | Bromsulfophthalein clearance and aminopyrine test in patients with Gilbert's syndrome. ( Bar-Meir, S; Bar-Tal, L; Papa, MZ; Peled, Y, 1986) |
| "This effect is higher in Gilbert's syndrome (GS) and this test has been used in the diagnosis of the syndrome." | 1.27 | Sex differences of nicotinate-induced hyperbilirubinemia in Gilbert's syndrome. Implication of bilitranslocase function. ( Baldini, G; Gentile, S; Lunazzi, G; Sottocasa, GL; Tiribelli, C, 1985) |
| "in the Rotor syndrome 131I-BSP uptake was delayed and liver clearance prolonged; 4." | 1.26 | [Contribution of sequential scintigraphy with 131I-BSP to the differential diagnosis of jaundice (author's transl)]. ( Cotul, S; Dumitrascu, D; Szántai, J; Tamás, S; Tapalaga, D, 1981) |
| "Two cases of Gilbert's syndrome and three cases of other diseases showed abnormally low plasma indocyanine green (ICG) clearance as contrated with normal or nearly normal plasma sulfobromphthalein (BSP) clearance." | 1.26 | The discrepancy between plasma clearance tests of indocyanine green (ICG) and sulfobromophthalein (BSP): --report of cases and a study of ICG-binding pattern of serum proteins. ( Adachi, Y; Onishi, S; Tanaka, S; Wakisaka, G; Yamamoto, T, 1976) |
| "mumol/l in 14 patients with Gilbert's syndrome." | 1.25 | [Diagnostic significance of serum bile acids]. ( Paumgartner, G; Preisig, R; Schwarz, HP, 1975) |
| "Patients with Gilbert's syndrome suffer from an abnormality which makes them jaundiced from time to time." | 1.25 | Gilbert's syndrome in patients with gallbladder stones. ( Peel, AL; Ritchie, HD, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (91.67) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shiota, T | 1 |
| Watanabe, A | 1 |
| Itoshima, T | 1 |
| Yamamoto, H | 1 |
| Takahashi, K | 1 |
| Nagashima, H | 1 |
| Kutz, K | 2 |
| Deres, M | 1 |
| Kandler, H | 1 |
| Gugler, R | 1 |
| Fevery, J | 1 |
| Stiehl, A | 1 |
| Reichen, J | 1 |
| Tapalaga, D | 1 |
| Szántai, J | 1 |
| Cotul, S | 1 |
| Tamás, S | 1 |
| Dumitrascu, D | 1 |
| Persico, M | 3 |
| Persico, E | 1 |
| Bakker, CT | 1 |
| Rigato, I | 1 |
| Amoroso, A | 1 |
| Torella, R | 1 |
| Bosma, PJ | 1 |
| Tiribelli, C | 5 |
| Ostrow, JD | 1 |
| Metreau, JM | 1 |
| Dhumeaux, D | 2 |
| Gisselbrecht, C | 1 |
| Preaux, AM | 1 |
| Berthelot, P | 2 |
| Carson, ER | 1 |
| Jones, EA | 1 |
| Hirata, H | 1 |
| Kamoi, I | 1 |
| Matsuura, K | 1 |
| Okolicsanyi, L | 1 |
| Ghidini, O | 2 |
| Orlando, R | 1 |
| Cortelazzo, S | 1 |
| Benedetti, G | 1 |
| Naccarato, R | 1 |
| Manitto, P | 1 |
| Martin, JF | 1 |
| Vierling, JM | 1 |
| Wolkoff, AW | 1 |
| Scharschmidt, BF | 1 |
| Vergalla, J | 1 |
| Waggoner, JG | 1 |
| Berk, PD | 1 |
| Adachi, Y | 1 |
| Yamamoto, T | 1 |
| Onishi, S | 1 |
| Tanaka, S | 1 |
| Wakisaka, G | 1 |
| Solís Herruzo, JA | 1 |
| Vallaperta, P | 1 |
| Schwarz, HP | 1 |
| Paumgartner, G | 1 |
| Preisig, R | 1 |
| Cartei, G | 1 |
| Chisesi, T | 1 |
| Cazzavillian, M | 1 |
| Barbui, T | 1 |
| Battista, R | 1 |
| Dini, E | 1 |
| Gentile, S | 3 |
| Baldini, G | 2 |
| Lunazzi, G | 2 |
| Sottocasa, GL | 3 |
| Lunazzi, GC | 1 |
| Bar-Meir, S | 1 |
| Bar-Tal, L | 1 |
| Papa, MZ | 1 |
| Peled, Y | 1 |
| Peel, AL | 1 |
| Ritchie, HD | 1 |
4 reviews available for sulfobromophthalein and Constitutional Liver Dysfunction
| Article | Year |
|---|---|
New insights into the classification and mechanisms of hereditary, chronic, non-haemolytic hyperbilirubinaemias.
Topics: Bilirubin; Chronic Disease; Coproporphyrins; Crigler-Najjar Syndrome; Female; Gilbert Disease; Glucu | 1978 |
Use of kinetic analysis and mathematical modeling in the study of metabolic pathways in vivo: applications to hepatic organic anion metabolism (second of two parts).
Topics: Animals; Anions; Bile; Bile Acids and Salts; Bilirubin; Cholestasis; Gilbert Disease; Humans; Indocy | 1979 |
Abnormal hepatic transport of indocyanine green in Gilbert's syndrome.
Topics: Adolescent; Adult; Aged; Bilirubin; Biological Transport; Child; Female; Gilbert Disease; Glucuronos | 1976 |
Mechanisms of hepatic uptake of organic anions.
Topics: Animals; Anions; Bile Pigments; Biological Transport; Biotransformation; Cell Membrane; Fatty Acids; | 1986 |
20 other studies available for sulfobromophthalein and Constitutional Liver Dysfunction
| Article | Year |
|---|---|
Two cases of constitutional unconjugated hyperbilirubinemia with marked retention of indocyanine green.
Topics: Adult; Gilbert Disease; Glucuronosyltransferase; Humans; Hyperbilirubinemia, Hereditary; Indocyanine | 1984 |
Effect of cimetidine on the metabolism of cholephilic dyes in Gilbert's syndrome.
Topics: Adolescent; Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bile; Bi | 1984 |
Effect of clofibrate on the metabolism of bilirubin, bromosulphophthalein and indocyanine green and on the biliary lipid composition in Gilbert's syndrome.
Topics: Adult; Bile; Bilirubin; Clofibrate; Female; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; | 1984 |
[Hyperbilirubinemia in liver diseases].
Topics: Anabolic Agents; Crigler-Najjar Syndrome; Estrogens; Gilbert Disease; Glucuronosyltransferase; Human | 1982 |
Familial unconjugated hyperbilirubinemia syndromes.
Topics: Animals; Bile Acids and Salts; Bilirubin; Crigler-Najjar Syndrome; Diagnosis, Differential; Disease | 1983 |
[Contribution of sequential scintigraphy with 131I-BSP to the differential diagnosis of jaundice (author's transl)].
Topics: Diagnosis, Differential; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Iodine Radioisotop | 1981 |
Hepatic uptake of organic anions affects the plasma bilirubin level in subjects with Gilbert's syndrome mutations in UGT1A1.
Topics: Adult; beta-Thalassemia; Bilirubin; Female; Gilbert Disease; Glucuronosyltransferase; Hemolysis; Hum | 2001 |
Constitutional unconjugated hyperbilirubinaemia.
Topics: Chronic Disease; Diagnosis, Differential; Gilbert Disease; Humans; Hyperbilirubinemia; Sulfobromopht | 1977 |
[Scintigraphic diagnosis of constitutional jaundice using 131I-B.S.P. (author's transl)].
Topics: Adolescent; Adult; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Iodine Radioisotopes; Ja | 1978 |
An evaluation of bilirubin kinetics with respect to the diagnosis of Gilbert's syndrome.
Topics: Adult; Bilirubin; Biological Transport; Female; Gilbert Disease; Humans; Hyperbilirubinemia, Heredit | 1978 |
The discrepancy between plasma clearance tests of indocyanine green (ICG) and sulfobromophthalein (BSP): --report of cases and a study of ICG-binding pattern of serum proteins.
Topics: Adult; Aged; Animals; Blood Proteins; Gilbert Disease; Hepatitis; Humans; Indocyanine Green; Jaundic | 1976 |
[Kinetics of bromsulphalein in the non congujate hyperbilirubinemias].
Topics: Drug Evaluation; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Kinetics; Liver; Liver Fun | 1975 |
[Compartmental models: theoretical aspects and applications to pharmocokinetics and clinical diagnosis].
Topics: Bilirubin; Diabetes Mellitus; Gilbert Disease; Glucose; Glucose Tolerance Test; Humans; Hyperbilirub | 1975 |
[Diagnostic significance of serum bile acids].
Topics: Adolescent; Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bilirubi | 1975 |
[Bromsulphalein clearance and hyperbilirubinemia in Gilbert's syndrome].
Topics: Biliary Tract; Gilbert Disease; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Liver; S | 1975 |
Abnormal hepatic uptake of low doses of sulfobromophthalein in Gilbert's syndrome: the role of reduced affinity of the plasma membrane carrier of organic anions.
Topics: Adolescent; Adult; Anions; Carrier Proteins; Cell Membrane; Female; Gilbert Disease; Humans; Hyperbi | 1990 |
The implication of bilitranslocase function in the impaired rifamycin SV metabolism in Gilbert's syndrome.
Topics: Adolescent; Adult; Ceruloplasmin; Female; Gilbert Disease; Humans; Male; Membrane Proteins; Middle A | 1985 |
Bromsulfophthalein clearance and aminopyrine test in patients with Gilbert's syndrome.
Topics: Adolescent; Adult; Aged; Aminopyrine; Breath Tests; Female; Gilbert Disease; Humans; Hyperbilirubine | 1986 |
Sex differences of nicotinate-induced hyperbilirubinemia in Gilbert's syndrome. Implication of bilitranslocase function.
Topics: Adolescent; Adult; Animals; Bilirubin; Binding, Competitive; Ceruloplasmin; Female; Gilbert Disease; | 1985 |
Gilbert's syndrome in patients with gallbladder stones.
Topics: Adult; Alkaline Phosphatase; Bilirubin; Cell Survival; Cholangiography; Cholecystectomy; Cholecystog | 1974 |