sulfobromophthalein has been researched along with Aging in 30 studies
Sulfobromophthalein: A phenolphthalein that is used as a diagnostic aid in hepatic function determination.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of aging on sulfobromophthalein (BSP) metabolism was studied in three groups of rats-BN/Bi female and WAG/Rij male and female rats-of different ages ranging from 3 to 30 months." | 7.66 | The effect of aging on the hepatic metabolism of sulfo-bromophthalein in BN/Bi female and WAG/Rij male and female rats. ( Kitani, K; Van Bezooijen, K; Zurcher, C, 1981) |
| "A "Protease inhibitor model of aging" has been proposed primarily based on observations on brain tissues exposed to a thiol protease inhibitor, leupeptin (Ivy et al." | 3.67 | Morphological, physiological and biochemical alterations in livers of rodents induced by protease inhibitors: a comparison with old livers. ( Ivy, GO; Kanai, S; Kitani, K; Nokubo, M; Ohta, M; Otsubo, K; Sato, Y, 1989) |
| "In order to elucidate the effect of aging on the biliary transport of organic anions, we examined the biliary transport maximum (Tm) for sulfobromophthalein (BSP) conjugated with glutathione in male and female Fischer-344 rats of various ages (3, 6, 24 and 30 months) during the constant intravenous infusion of conjugated BSP." | 3.67 | The age-dependent decline in the biliary transport maximum of conjugated sulfobromophthalein in the rat. ( Kanai, S; Kitani, K; Nokubo, M; Sato, Y, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (96.67) | 18.7374 |
| 1990's | 1 (3.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| COMBES, B | 1 |
| STAKELUM, GS | 1 |
| CALLOWAY, NO | 1 |
| MERRILL, RS | 1 |
| Freston, JW | 1 |
| Englert, E | 1 |
| van Bezooijen, CF | 2 |
| Sakkee, AN | 1 |
| Knook, DL | 3 |
| Okumura, H | 1 |
| Fukuda, N | 1 |
| Aramaki, T | 1 |
| Katsuta, Y | 1 |
| Satomura, K | 1 |
| Sato, T | 1 |
| Yano, T | 1 |
| Kitani, K | 5 |
| Zurcher, C | 1 |
| Van Bezooijen, K | 1 |
| Angeletti, RH | 1 |
| Bergwerk, AJ | 1 |
| Novikoff, PM | 1 |
| Wolkoff, AW | 1 |
| Skaunic, V | 6 |
| Utili, R | 1 |
| Abernathy, CO | 1 |
| Aron, SA | 1 |
| Zimmerman, HJ | 1 |
| Cagen, SZ | 1 |
| Gibson, JE | 1 |
| Bell, JU | 1 |
| Ecobichon, DJ | 1 |
| Kampmann, JP | 1 |
| Sinding, J | 1 |
| Moller-Jorgensen, I | 1 |
| Klaassen, CD | 1 |
| Ohta, M | 2 |
| Kanai, S | 4 |
| Nokubo, M | 3 |
| Sato, Y | 3 |
| Otsubo, K | 2 |
| Ivy, GO | 1 |
| Carrillo, MC | 1 |
| Fujita, S | 1 |
| Kitagawa, H | 1 |
| Papanayiotou, P | 1 |
| Papanicolaou, NT | 1 |
| Dontas, AS | 1 |
| Koff, RS | 1 |
| Garvey, AJ | 1 |
| Burney, SW | 1 |
| Bell, B | 1 |
| de Leeuw-Israel, FR | 3 |
| Hollander, CF | 3 |
| Means, BJ | 1 |
| Lamy, PP | 1 |
| Nerad, V | 4 |
| Jadrná, J | 1 |
| Fendrychová, M | 1 |
| Halberstadt, P | 1 |
| Fendrichová, M | 1 |
| Arp-Neefjes, JM | 2 |
30 other studies available for sulfobromophthalein and Aging
| Article | Year |
|---|---|
Maturation of the sulfobromophthalein sodium-glutathione conjugating system in rat liver.
Topics: Aging; Glutathione; Liver; Liver Function Tests; Sodium; Sodium, Dietary; Sulfobromophthalein | 1962 |
THE AGING ADULT LIVER. I. BROMSULPHALEIN AND BILIRUBIN CLEARANCES.
Topics: Aging; Bilirubin; Geriatrics; Liver Function Tests; Pharmacology; Sulfobromophthalein | 1965 |
The influence of age and excessive body weight on the distribution and metabolism of bromsulphalein.
Topics: Adult; Aged; Aging; Biological Transport; Blood Volume; Body Weight; Female; Humans; Injections, Int | 1967 |
Meclofenoxate decreases protein and albumin synthesis in hepatocytes isolated from old rats.
Topics: Aging; Albumins; Animals; Female; Glycolates; In Vitro Techniques; Liver; Meclofenoxate; Protein Bio | 1983 |
Rotor's syndrome: a study on variations in pigment metabolism with age.
Topics: Adolescent; Adult; Aging; Bilirubin; Female; Humans; Hyperbilirubinemia, Hereditary; Male; Sulfobrom | 1982 |
The effect of aging on the hepatic metabolism of sulfo-bromophthalein in BN/Bi female and WAG/Rij male and female rats.
Topics: Aging; Animals; Bile; Biological Transport; Female; Kinetics; Liver; Male; Organ Size; Rats; Sulfobr | 1981 |
The isolated hepatocyte: a cellular model for aging studies.
Topics: Aging; Animals; Cell Survival; Female; In Vitro Techniques; Liver; Lysosomes; Models, Biological; Ox | 1980 |
Dichotomous development of the organic anion transport protein in liver and choroid plexus.
Topics: Aging; Animals; Animals, Newborn; Biological Transport; Choroid Plexus; Female; Gene Expression Regu | 1998 |
Model systems for studies on cellular basis of organ ageing.
Topics: Aging; Animals; Endothelium; Kupffer Cells; Liver; Liver Function Tests; Liver Regeneration; Lysosom | 1977 |
[Hepatic excretion of exogenous dyes. New observations and prospects].
Topics: Aging; Animals; Humans; Indocyanine Green; Kinetics; Liver; Models, Biological; Rats; Sulfobromophth | 1979 |
In vivo effects of Escherichia coli endotoxin on sulfobromophthalein clearance in the guinea-pig.
Topics: Aging; Animals; Animals, Newborn; Aspartate Aminotransferases; Endotoxins; Escherichia coli; Female; | 1977 |
Characteristics of hepatic excretory function during development.
Topics: Aging; Animals; Bile; Bile Ducts; Biological Transport; Digoxin; Ligation; Liver; Ouabain; Rats; Sul | 1979 |
The development of kinetic parameters of hepatic drug-metabolizing enzymes in perinatal rats.
Topics: Aging; Animals; Animals, Newborn; Anisoles; Body Weight; DNA; Esterases; Female; Fetus; Glutathione; | 1975 |
Effect of age on liver function.
Topics: Aged; Aging; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Electrophoresis, Paper; F | 1975 |
Biliary excretion of drugs: role of ligandin in newborn immaturity and in the action of microsomal enzyme inducers.
Topics: Aging; Animals; Animals, Newborn; Bile; Biotransformation; Carrier Proteins; Enzyme Induction; Gluta | 1975 |
Morphological, physiological and biochemical alterations in livers of rodents induced by protease inhibitors: a comparison with old livers.
Topics: Aging; Animals; Biological Transport; Dolichols; Leucine; Leupeptins; Liver; Male; Mice; Mice, Inbre | 1989 |
Differences in the influence of diet on hepatic glutathione S-transferase activity and glutathione content between young and old C57 black female mice.
Topics: Aging; Animals; Butanones; Dietary Proteins; Dinitrochlorobenzene; Epoxy Compounds; Female; Glutathi | 1989 |
The age-dependent decline in the biliary transport maximum of conjugated sulfobromophthalein in the rat.
Topics: Aging; Animals; Bile; Biological Transport; Female; Glutathione; Infusions, Intravenous; Male; Rats; | 1988 |
The hepatic handling of sulfobromphthalein in aging Fischer-344 rats: in vivo and in vitro studies.
Topics: Aging; Animals; Bile; Biological Transport; Female; Glutathione; Liver; Male; Rats; Rats, Inbred F34 | 1985 |
[Comparative study of BSP excretion in young and elderly subjects].
Topics: Adult; Aged; Aging; Alkaline Phosphatase; Aminohippuric Acids; Bilirubin; Humans; Inulin; Kidney Fun | 1969 |
Absence of an age effect on sulfobromophthalein retention in healthy men.
Topics: Adult; Aged; Aging; Humans; Liver Function Tests; Male; Middle Aged; Sulfobromophthalein | 1973 |
On the role of hepatic cell ploidy in changes in liver function with age and following partial hepatectomy.
Topics: Aging; Animals; Body Weight; Diploidy; Female; Hepatectomy; Liver; Liver Function Tests; Organ Size; | 1973 |
Diagnostic tests, drugs, and the geriatric patient.
Topics: Aged; Aging; Angiocardiography; Barium Sulfate; Cells; Contrast Media; Diabetes Mellitus; Diagnosis; | 1974 |
[The dye excretion ability of the liver in relation to age. Changes in the relative storage ability and maximum secretion ability of the liver for bromsulphthalein].
Topics: Adolescent; Adult; Aged; Aging; Humans; Liver; Male; Middle Aged; Sulfobromophthalein | 1966 |
[Age dependence of the normal values of the bromsulphthalein test].
Topics: Adolescent; Adult; Aging; Humans; Liver Function Tests; Male; Sulfobromophthalein | 1967 |
[Determination of the action mechanism of disorders in bromsulphalein kinetics due to old age].
Topics: Adult; Age Factors; Aged; Aging; Animals; Humans; Kinetics; Liver; Liver Circulation; Middle Aged; R | 1970 |
[Mechanism of decline in the liver's relative storage capacity for bromsulphalein with advancing age. I. Significance of the storage capacity of isolated hepatocytes and of the volume of hepatic storage mass].
Topics: Aging; Animals; Humans; Liver; Male; Middle Aged; Portal Vein; Rats; Sulfobromophthalein; Thrombosis | 1970 |
[Mechanism of the decline in liver relative storage capacity for bromsulphthalein with advancing age. II. Significance of reduced hepatic blood flow].
Topics: Adult; Aged; Aging; Humans; Liver; Liver Circulation; Male; Middle Aged; Sulfobromophthalein | 1970 |
Bromsulphalein (BSP) clearance in ageing rats.
Topics: Aging; Animals; Bile; Liver; Liver Diseases; Liver Function Tests; Rats; Sulfobromophthalein | 1968 |
Hepatic storage and maximal biliary excretion of bromsulphalein (BSP) in young and old rats.
Topics: Aging; Animals; Bile; Female; Liver; Mathematics; Plasma Volume; Polyploidy; Rats; Sulfobromophthale | 1969 |