Page last updated: 2024-10-20

sulfites and Colorectal Cancer

sulfites has been researched along with Colorectal Cancer in 40 studies

Sulfites: Inorganic salts of sulfurous acid.
sulfites : Any sulfurous acid derivative that is a salt or an ester of sulfurous acid.
organosulfonate oxoanion : An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid.
sulfite : A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3).

Research Excerpts

ExcerptRelevanceReference
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"It has been proposed that human colorectal tumors can be classified into two groups: one in which methylation is rare, and another with methylation of several loci associated with a "CpG island methylated phenotype (CIMP)," characterized by preferential proximal location in the colon, but otherwise poorly defined."1.33Colorectal cancer "methylator phenotype": fact or artifact? ( Anacleto, C; Caballero, O; Camargo, AA; Leopoldino, AM; Lopes, A; Pena, SD; Rocha, JC; Rossi, B; Simpson, AJ; Soares, FA, 2005)
"Sporadic colorectal cancers often arise from a region of cells characterized by a "field defect" that has not been well defined molecularly."1.33MGMT promoter methylation and field defect in sporadic colorectal cancer. ( Alberts, DS; Buckmeier, J; Einspahr, JG; Hamilton, SR; Hernandez, NS; Houlihan, PS; Issa, JP; Kondo, Y; Krouse, RS; Prasad, AR; Rosner, GL; Shen, L; Vilaythong, J; Xiao, L, 2005)
"Of 272 colorectal cancers evaluated, most showed PMR either <1 or >10, and promoter methylation (PMR >4) was tightly associated with loss of respective protein expression (P < 10(-16))."1.33Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis. ( Brahmandam, M; Cantor, M; Fuchs, CS; Kawasaki, T; Kirkner, GJ; Laird, PW; Loda, M; Makrigiorgos, GM; Ogino, S; Spiegelman, D; Weisenberger, DJ, 2006)
"Among 76 American Joint Committee on Cancer stage I to IV patients who had undergone curative surgical resection, overall survival was significantly poorer in patients with hypermethylated ID4 bearing tumors (P = 0."1.32Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis. ( Bilchik, AJ; Fujimoto, A; Hoon, DS; Shinozaki, M; Takeuchi, H; Umetani, N, 2004)
"These results suggested that colorectal cancer with both p16 and p14 methylation has the same invasiveness at a smaller size compared to that of the cancer with neither p16 nor p14 methylation."1.31Colorectal cancers with both p16 and p14 methylation show invasive characteristics. ( Akiyama, S; Hibi, K; Ito, K; Kasai, Y; Koike, M; Nakao, A; Nakayama, H, 2002)
"Most colorectal cancer tissues showed similar results."1.31Methylation status and expression of human telomerase reverse transcriptase mRNA in relation to hypermethylation of the p16 gene in colorectal cancers as analyzed by bisulfite PCR-SSCP. ( Fujita, S; Fukayama, N; Kakizoe, T; Maekawa, M; Nomoto, K; Sugano, K; Ushiama, M, 2002)
"We thus define a pathway in colorectal cancer that appears to be responsible for the majority of sporadic tumors with mismatch repair deficiency."1.30CpG island methylator phenotype in colorectal cancer. ( Ahuja, N; Baylin, SB; Herman, JG; Issa, JP; Ohe-Toyota, M; Toyota, M, 1999)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (7.50)18.2507
2000's24 (60.00)29.6817
2010's10 (25.00)24.3611
2020's3 (7.50)2.80

Authors

AuthorsStudies
Szigeti, KA1
Barták, BK1
Nagy, ZB1
Zsigrai, S1
Papp, M1
Márkus, E1
Igaz, P1
Takács, I1
Molnár, B2
Kalmár, A2
Jensen, SØ1
Øgaard, N1
Nielsen, HJ1
Bramsen, JB1
Andersen, CL1
Huang, Q1
Yang, Q1
Mo, M1
Ye, X1
Zhang, J1
Zhang, L1
Chen, B1
Li, J2
Cai, C1
Hussmann, D1
Hansen, LL1
Alonso, S1
González, B1
Alibés, A1
Perucho, M1
Gries, J1
Schumacher, D1
Arand, J1
Lutsik, P1
Markelova, MR1
Fichtner, I1
Walter, J1
Sers, C1
Tierling, S1
Xiao, Z1
Li, B1
Wang, G1
Zhu, W1
Wang, Z1
Lin, J1
Xu, A1
Wang, X1
Kaneda, A1
Yagi, K1
Tsai, MH1
Chen, WC1
Yu, SL1
Chen, CC1
Jao, TM1
Huang, CY1
Tzeng, ST1
Yen, SJ1
Yang, YC1
Péterfia, B1
Hollósi, P1
Wichmann, B1
Bodor, A1
Patai, ÁV1
Schöller, A1
Krenács, T1
Tulassay, Z1
Nagasaka, T1
Tanaka, N2
Cullings, HM1
Sun, DS1
Sasamoto, H1
Uchida, T1
Koi, M1
Nishida, N1
Naomoto, Y1
Boland, CR1
Matsubara, N1
Goel, A1
Baba, Y1
Nosho, K1
Shima, K1
Huttenhower, C1
Hazra, A1
Giovannucci, EL1
Fuchs, CS2
Ogino, S2
Miroglio, A1
Jammes, H1
Tost, J1
Ponger, L1
Gut, IG1
El Abdalaoui, H1
Coste, J1
Chaussade, S1
Arimondo, PB1
Lamarque, D1
Dandolo, L1
Suh, ER1
Ha, CS1
Rankin, EB1
Toyota, M4
Traber, PG1
Hibi, K3
Koike, M2
Nakayama, H3
Fujitake, S1
Kasai, Y2
Ito, K3
Akiyama, S3
Nakao, A3
Yamaguchi, S1
Asao, T1
Nakamura, J1
Ide, M1
Kuwano, H1
Yokoyama, T1
Sagara, J1
Guan, X1
Masumoto, J1
Takeoka, M1
Komiyama, Y1
Miyata, K1
Higuchi, K1
Taniguchi, S1
Obata, T1
Satoh, A2
Sasaki, Y2
Ogi, K1
Akino, K2
Suzuki, H2
Murai, M1
Kikuchi, T1
Mita, H2
Itoh, F1
Issa, JP4
Tokino, T2
Imai, K2
Kodera, Y1
Ikeda, H1
Morimoto, Y1
Kanaseki, T1
Takamura, Y1
Soejima, H1
Urano, T1
Yanagihara, K1
Endo, T1
Hinoda, Y1
Fujita, M1
Hosokawa, M1
Sato, N1
Umetani, N2
Takeuchi, H1
Fujimoto, A1
Shinozaki, M1
Bilchik, AJ1
Hoon, DS2
Hesson, LB1
Wilson, R1
Morton, D1
Adams, C1
Walker, M1
Maher, ER1
Latif, F1
Anacleto, C1
Leopoldino, AM1
Rossi, B1
Soares, FA1
Lopes, A1
Rocha, JC1
Caballero, O1
Camargo, AA1
Simpson, AJ1
Pena, SD1
Shen, L2
Kondo, Y1
Rosner, GL1
Xiao, L1
Hernandez, NS1
Vilaythong, J1
Houlihan, PS1
Krouse, RS1
Prasad, AR1
Einspahr, JG1
Buckmeier, J1
Alberts, DS1
Hamilton, SR2
Shi, X1
Zhao, C1
Lv, S1
Xu, G1
Kawasaki, T1
Brahmandam, M1
Cantor, M1
Kirkner, GJ1
Spiegelman, D1
Makrigiorgos, GM1
Weisenberger, DJ1
Laird, PW3
Loda, M1
de Maat, MF1
Sunami, E1
Hiramatsu, S1
Martinez, S1
Bredberg, A1
Bodmer, W1
Menigatti, M1
Pedroni, M1
Verrone, AM1
Borghi, F1
Scarselli, A1
Benatti, P1
Losi, L1
Di Gregorio, C1
Schär, P1
Marra, G1
Ponz de Leon, M1
Roncucci, L1
Catalano, PJ1
Benson, AB1
O'Dwyer, P1
Xiong, Z1
Ahuja, N1
Ohe-Toyota, M1
Herman, JG1
Baylin, SB1
Maekawa, M2
Sugano, K2
Kashiwabara, H1
Ushiama, M2
Fujita, S2
Yoshimori, M1
Kakizoe, T2
Eads, CA1
Danenberg, KD1
Kawakami, K1
Saltz, LB1
Blake, C1
Shibata, D2
Danenberg, PV1
Zheng, S1
Chen, P1
McMillan, A1
Lafuente, A1
Lafuente, MJ1
Ballesta, A1
Trias, M1
Wiencke, JK1
Sato, F2
Harpaz, N1
Xu, Y1
Yin, J2
Mori, Y1
Zou, TT1
Wang, S1
Desai, K1
Leytin, A1
Selaru, FM1
Abraham, JM1
Meltzer, SJ2
Nomoto, K1
Fukayama, N1
Toyooka, S1
Toyooka, KO1
Harada, K1
Miyajima, K1
Makarla, P1
Sathyanarayana, UG1
Shivapurkar, N1
Gazdar, AF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Circulating Tumor DNA Guided vs Opportunistic Colonoscopy Screening for CRC Detection After Acute Colonic Diverticulitis - the Diverticulitis Study[NCT06023004]250 participants (Anticipated)Observational2022-05-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for sulfites and Colorectal Cancer

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Trials

1 trial available for sulfites and Colorectal Cancer

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Other Studies

39 other studies available for sulfites and Colorectal Cancer

ArticleYear
Methodological and Biological Factors Influencing Global DNA Methylation Results Measured by LINE-1 Pyrosequencing Assay in Colorectal Tissue and Liquid Biopsy Samples.
    International journal of molecular sciences, 2022, Oct-01, Volume: 23, Issue:19

    Topics: Aged; Biological Factors; Biopsy; Cell-Free Nucleic Acids; Colorectal Neoplasms; DNA; DNA Methylatio

2022
Enhanced Performance of DNA Methylation Markers by Simultaneous Measurement of Sense and Antisense DNA Strands after Cytosine Conversion.
    Clinical chemistry, 2020, 07-01, Volume: 66, Issue:7

    Topics: Aged; Biomarkers, Tumor; Circulating Tumor DNA; Colorectal Neoplasms; Cytosine; DNA Methylation; DNA

2020
Screening of exon methylation biomarkers for colorectal cancer via LC-MS/MS strategy.
    Journal of mass spectrometry : JMS, 2017, Volume: 52, Issue:12

    Topics: Adult; Aged; Biomarkers, Tumor; Carrier Proteins; Chromatography, High Pressure Liquid; Colorectal N

2017
Methylation-Sensitive High Resolution Melting (MS-HRM).
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1708

    Topics: Breast Neoplasms; Colorectal Neoplasms; DNA Methylation; DNA, Neoplasm; Feces; Female; Humans; Male;

2018
Analysis of Somatic DNA Methylation Alterations of Genes Encoding Cell Surface Metallopeptidases in Colorectal Cancer.
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1731

    Topics: ADAMTS Proteins; Cell Line, Tumor; Cell Membrane; Colorectal Neoplasms; CpG Islands; Databases, Gene

2018
Bi-PROF: bisulfite profiling of target regions using 454 GS FLX Titanium technology.
    Epigenetics, 2013, Volume: 8, Issue:7

    Topics: Animals; Base Sequence; Colorectal Neoplasms; DNA Methylation; DNA Primers; Humans; Mice; Molecular

2013
Validation of methylation-sensitive high-resolution melting (MS-HRM) for the detection of stool DNA methylation in colorectal neoplasms.
    Clinica chimica acta; international journal of clinical chemistry, 2014, Apr-20, Volume: 431

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Colorectal Neoplasms; DNA Methylation; Feces; Fem

2014
Quantitative DNA methylation analysis for epigenotyping of colorectal cancer.
    Methods in molecular biology (Clifton, N.J.), 2015, Volume: 1238

    Topics: Cluster Analysis; Colorectal Neoplasms; DNA Methylation; Epigenomics; Genotyping Techniques; Humans;

2015
DNA Hypermethylation of SHISA3 in Colorectal Cancer: An Independent Predictor of Poor Prognosis.
    Annals of surgical oncology, 2015, Volume: 22 Suppl 3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Case-Control Studies; Colorectal

2015
Bisulfite-Based DNA Methylation Analysis from Recent and Archived Formalin-Fixed, Paraffin Embedded Colorectal Tissue Samples.
    Pathology oncology research : POR, 2015, Volume: 21, Issue:4

    Topics: Colorectal Neoplasms; DNA; DNA Methylation; Formaldehyde; Humans; Paraffin; Paraffin Embedding; Repr

2015
Analysis of fecal DNA methylation to detect gastrointestinal neoplasia.
    Journal of the National Cancer Institute, 2009, Sep-16, Volume: 101, Issue:18

    Topics: Biomarkers, Tumor; Colorectal Neoplasms; Confidence Intervals; Disease Progression; DNA Methylation;

2009
Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosis.
    Gastroenterology, 2010, Volume: 139, Issue:6

    Topics: Aged; Biomarkers, Tumor; Biopsy; Colorectal Neoplasms; CpG Islands; DNA Methylation; Female; Genomic

2010
Specific hypomethylated CpGs at the IGF2 locus act as an epigenetic biomarker for familial adenomatous polyposis colorectal cancer.
    Epigenomics, 2010, Volume: 2, Issue:3

    Topics: Adenomatous Polyposis Coli; Biomarkers; Cluster Analysis; Colorectal Neoplasms; CpG Islands; DNA Met

2010
DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines.
    The Journal of biological chemistry, 2002, Sep-27, Volume: 277, Issue:39

    Topics: Animals; Azacitidine; Base Sequence; Blotting, Western; Cloning, Molecular; Colorectal Neoplasms; Co

2002
A cancer-prone case with a background of methylation of p16 tumor suppressor gene.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:3

    Topics: Colorectal Neoplasms; DNA Methylation; Esophageal Neoplasms; Genes, p16; Humans; Immunohistochemistr

2003
High frequency of DAP-kinase gene promoter methylation in colorectal cancer specimens and its identification in serum.
    Cancer letters, 2003, May-08, Volume: 194, Issue:1

    Topics: Apoptosis Regulatory Proteins; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Colo

2003
Colorectal cancers with both p16 and p14 methylation show invasive characteristics.
    Japanese journal of cancer research : Gann, 2002, Volume: 93, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; DNA Met

2002
Methylation of ASC/TMS1, a proapoptotic gene responsible for activating procaspase-1, in human colorectal cancer.
    Cancer letters, 2003, Dec-08, Volume: 202, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Azacitidine; CARD Signaling Adaptor Proteins; Case-Contro

2003
Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Dec-15, Volume: 9, Issue:17

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Cell Sep

2003
CDH13 promoter region is specifically methylated in poorly differentiated colorectal cancer.
    British journal of cancer, 2004, Mar-08, Volume: 90, Issue:5

    Topics: Cadherins; Carcinoma, Squamous Cell; Case-Control Studies; Cell Differentiation; Colorectal Neoplasm

2004
Epigenetic inactivation of class II transactivator (CIITA) is associated with the absence of interferon-gamma-induced HLA-DR expression in colorectal and gastric cancer cells.
    Oncogene, 2004, Nov-25, Volume: 23, Issue:55

    Topics: Blotting, Western; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Chromatin Immunoprecipitation; Colo

2004
Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Nov-15, Volume: 10, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Carcinoma; Cell Differentiation; Cell Line, Tumor; Colo

2004
CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations.
    Oncogene, 2005, Jun-02, Volume: 24, Issue:24

    Topics: Base Sequence; Brain; Cell Line, Tumor; Cloning, Molecular; Colonic Neoplasms; Colorectal Neoplasms;

2005
Colorectal cancer "methylator phenotype": fact or artifact?
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Colonic Neoplasms; Colorectal Neoplasms; CpG

2005
MGMT promoter methylation and field defect in sporadic colorectal cancer.
    Journal of the National Cancer Institute, 2005, Sep-21, Volume: 97, Issue:18

    Topics: Biomarkers, Tumor; Cell Line, Tumor; Colorectal Neoplasms; DNA Methylation; Epigenesis, Genetic; Gen

2005
Methylation analysis of hMLH1 gene promoter by a bisulfite-sensitive single-strand conformation polymorphism-capillary electrophoresis method.
    Biomedical chromatography : BMC, 2006, Volume: 20, Issue:8

    Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Carrier Proteins; Colorectal Neoplasms; DNA Methy

2006
Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis.
    The Journal of molecular diagnostics : JMD, 2006, Volume: 8, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Collagen Type II; Colorectal Neoplasms; Cycl

2006
Methylation of p16 and Ras association domain family protein 1a during colorectal malignant transformation.
    Molecular cancer research : MCR, 2006, Volume: 4, Issue:5

    Topics: Alu Elements; Base Sequence; Cell Transformation, Neoplastic; Colorectal Neoplasms; DNA Methylation;

2006
Cytostatic drug treatment causes seeding of gene promoter methylation.
    European journal of cancer (Oxford, England : 1990), 2007, Volume: 43, Issue:5

    Topics: Antimetabolites, Antineoplastic; Colorectal Neoplasms; DNA Methylation; Drug Resistance, Neoplasm; E

2007
O6-methylguanine-DNA methyltransferase promoter hypermethylation in colorectal carcinogenesis.
    Oncology reports, 2007, Volume: 17, Issue:6

    Topics: Aged; Aged, 80 and over; Carcinoma; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cyclin-De

2007
Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Oct-15, Volume: 13, Issue:20

    Topics: Aged; Antineoplastic Agents; Colorectal Neoplasms; CpG Islands; DNA Methylation; Female; Fluorouraci

2007
COBRA: a sensitive and quantitative DNA methylation assay.
    Nucleic acids research, 1997, Jun-15, Volume: 25, Issue:12

    Topics: Base Sequence; Colorectal Neoplasms; Dinucleoside Phosphates; DNA; DNA Methylation; DNA, Neoplasm; G

1997
CpG island methylator phenotype in colorectal cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jul-20, Volume: 96, Issue:15

    Topics: Adaptor Proteins, Signal Transducing; Age Factors; Carrier Proteins; Cloning, Molecular; Colorectal

1999
DNA methylation analysis using bisulfite treatment and PCR-single-strand conformation polymorphism in colorectal cancer showing microsatellite instability.
    Biochemical and biophysical research communications, 1999, Sep-07, Volume: 262, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Base Sequence; Calibration; Carrier Proteins; Colorectal Neopl

1999
MethyLight: a high-throughput assay to measure DNA methylation.
    Nucleic acids research, 2000, Apr-15, Volume: 28, Issue:8

    Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alleles; Carri

2000
Correlations of partial and extensive methylation at the p14(ARF) locus with reduced mRNA expression in colorectal cancer cell lines and clinicopathological features in primary tumors.
    Carcinogenesis, 2000, Volume: 21, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Base Sequence; Colorectal Neoplasms; CpG Islands; DNA Methylation; D

2000
Hypermethylation of the p14(ARF) gene in ulcerative colitis-associated colorectal carcinogenesis.
    Cancer research, 2002, Feb-15, Volume: 62, Issue:4

    Topics: Base Sequence; Colitis, Ulcerative; Colorectal Neoplasms; DNA Methylation; Humans; Intestinal Mucosa

2002
Methylation status and expression of human telomerase reverse transcriptase mRNA in relation to hypermethylation of the p16 gene in colorectal cancers as analyzed by bisulfite PCR-SSCP.
    Japanese journal of clinical oncology, 2002, Volume: 32, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Cell Transformation, Neoplastic; Colorectal

2002
Aberrant methylation of the CDH13 (H-cadherin) promoter region in colorectal cancers and adenomas.
    Cancer research, 2002, Jun-15, Volume: 62, Issue:12

    Topics: Adenoma; Cadherins; Colorectal Neoplasms; DNA Methylation; Humans; Intestinal Mucosa; Luciferases; P

2002