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sulfisoxazole and Otitis Media

sulfisoxazole has been researched along with Otitis Media in 44 studies

Sulfisoxazole: A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.
sulfisoxazole : A sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of gram-negative and gram-positive organisms.

Otitis Media: Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.

Research Excerpts

ExcerptRelevanceReference
"The rate of recovery of oropharyngeal penicillin-resistant Streptococcus pneumoniae and aerobic and anaerobic beta-lactamase-producing bacteria (BLPB) from children who received a 4- to 6-month course of prophylaxis with amoxicillin or sulfisoxazole for otitis media was investigated monthly over 9 months."9.08Prophylaxis with amoxicillin or sulfisoxazole for otitis media: effect on the recovery of penicillin-resistant bacteria from children. ( Brook, I; Gober, AE, 1996)
"In a prospective randomized open study, 111 young children with otitis media were orally treated during 10 days with Pediazole (50 mg/kg/day in 3 divided doses) or amoxicillin + clavulanic acid (40 mg/kg/day in 3 or 4 divided doses) for efficacy and safety evaluation."9.06[Acute otitis media in children: a randomized and open clinical trial of the efficacy of 2 major antibiotics (erythromycin ethylsuccinate/acetyl sulfafurazole vs amoxicillin/clavulanic acid)]. ( Bégué, P; Broussin, B; Garabedian, N; Quinet, B; Rivière, F; Sounthavong, JP, 1990)
"Sulfisoxazole, 75 mg/kg/d in two divided doses for 3 months, was administered in a double-blind placebo crossover study to 35 children aged 6 months to 5 years who had frequent recurring episodes of otitis media."9.05Sulfisoxazole chemoprophylaxis for frequent otitis media. ( Foshee, WS; Liston, TE; Pierson, WD, 1983)
"A fixed combination of erythromycin ethylsuccinate and sulfisoxazole acetyl (erythromycin-sulfa) was compared with amoxicillin for the treatment of acute otitis media (AOM) in children."9.05Erythromycin-sulfisoxazole vs amoxicillin in the treatment of acute otitis media in children. A double-blind, multiple-dose comparative study. ( Chang, MJ; Chhabra, OP; Gold, AJ; Khan, WN; Marks, LA; Reddy, S; Rodriguez, WJ; Sait, T; Schwartz, RH, 1985)
"Sulfisoxazole, 75 mg per kg per day, was administered for 13 weeks to all children with otitis media recurring at a rate of at least once every other month."7.67Sulfisoxazole chemoprophylaxis and recurrent otitis media. ( Harbison, R; Liston, TE, 1984)
"Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media."7.66Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982)
"The rate of recovery of oropharyngeal penicillin-resistant Streptococcus pneumoniae and aerobic and anaerobic beta-lactamase-producing bacteria (BLPB) from children who received a 4- to 6-month course of prophylaxis with amoxicillin or sulfisoxazole for otitis media was investigated monthly over 9 months."5.08Prophylaxis with amoxicillin or sulfisoxazole for otitis media: effect on the recovery of penicillin-resistant bacteria from children. ( Brook, I; Gober, AE, 1996)
"In a prospective randomized open study, 111 young children with otitis media were orally treated during 10 days with Pediazole (50 mg/kg/day in 3 divided doses) or amoxicillin + clavulanic acid (40 mg/kg/day in 3 or 4 divided doses) for efficacy and safety evaluation."5.06[Acute otitis media in children: a randomized and open clinical trial of the efficacy of 2 major antibiotics (erythromycin ethylsuccinate/acetyl sulfafurazole vs amoxicillin/clavulanic acid)]. ( Bégué, P; Broussin, B; Garabedian, N; Quinet, B; Rivière, F; Sounthavong, JP, 1990)
"Sulfisoxazole, 75 mg/kg/d in two divided doses for 3 months, was administered in a double-blind placebo crossover study to 35 children aged 6 months to 5 years who had frequent recurring episodes of otitis media."5.05Sulfisoxazole chemoprophylaxis for frequent otitis media. ( Foshee, WS; Liston, TE; Pierson, WD, 1983)
"A fixed combination of erythromycin ethylsuccinate and sulfisoxazole acetyl (erythromycin-sulfa) was compared with amoxicillin for the treatment of acute otitis media (AOM) in children."5.05Erythromycin-sulfisoxazole vs amoxicillin in the treatment of acute otitis media in children. A double-blind, multiple-dose comparative study. ( Chang, MJ; Chhabra, OP; Gold, AJ; Khan, WN; Marks, LA; Reddy, S; Rodriguez, WJ; Sait, T; Schwartz, RH, 1985)
"The findings of this study document a preference for amoxicillin as the initial antibiotic for a new episode of acute otitis media."3.69Otitis media-related antibiotic prescribing patterns, outcomes, and expenditures in a pediatric medicaid population. ( Berman, S; Bondy, J; Byrns, PJ; Lezotte, D; Smith, PJ, 1997)
"Sulfisoxazole, 75 mg per kg per day, was administered for 13 weeks to all children with otitis media recurring at a rate of at least once every other month."3.67Sulfisoxazole chemoprophylaxis and recurrent otitis media. ( Harbison, R; Liston, TE, 1984)
"Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media."3.66Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982)
" In this study, mean daily dosage was 40-50 mg/kg for cefaclor and 50 mg/kg ES + 150 mg/kg sulfamide for Pediazole."2.67[An open randomized trial, Pediazole versus cefaclor in the treatment of acute otitis media in children]. ( Bedbeder, P; Boucherat, M; Bouhanna, CA; Cohen, R; de La Rocque, F; Geslin, P; Peynegre, R; Reinert, P, 1991)
"Otitis media has long been recognized as one of the most common diseases of childhood."2.66Prevention of recurrent acute otitis media: chemoprophylaxis versus tympanostomy tubes. ( Arnold, JE; Erhardt, JB; Getts, A; Gonzalez, C; Kolmer, JW; Kueser, TJ; Pratt, SR; Sachs, M; Woody, EA, 1986)
"However, children with a history of serous otitis media did significantly better on placebo than did those on antihistamine, and children without a history of serous otitis media did significantly better on antihistamine than did those on placebo."2.65Prevention and treatment of serous otitis media with an oral antihistamine. A double-blind study in pediatric practice. ( Cunningham, D; Hengerer, A; Hoekelman, RA; Klein, SW; Olson, AL; Perrin, J; Roghmann, KJ, 1980)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199031 (70.45)18.7374
1990's11 (25.00)18.2507
2000's2 (4.55)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
TASAKA, S1
Koivunen, P1
Uhari, M1
Luotonen, J1
Kristo, A1
Raski, R1
Pokka, T1
Alho, OP1
Dawson, C1
Wood, TR1
Rose, L1
Hanna, L1
Liston, TE2
Foshee, WS1
Pierson, WD1
Harbison, R1
de Castro, FJ1
Jaeger, RW1
Martin, L1
Temeck, JW1
Tournour, B1
Klein, SW1
Olson, AL1
Perrin, J1
Cunningham, D1
Hengerer, A1
Hoekelman, RA1
Roghmann, KJ1
Paradise, JL2
Krause, PJ1
Owens, NJ1
Nightingale, CH1
Klimek, JJ1
Lehmann, WB1
Quintiliani, R1
Szold, PD1
Schwartz, RH3
Schwartz, DM1
Grundfast, KM1
François, M1
Bonacorsi, S1
Bingen, E2
Sheeran, PW1
Smith, AL1
Mendelman, PL1
Brook, I1
Gober, AE1
Berman, S1
Byrns, PJ1
Bondy, J1
Smith, PJ1
Lezotte, D1
Heiger, AA1
Giebink, GS1
Rako, J1
Lambert-Zechovsky, N1
Mariani-Kurkdjian, P1
Doit, C1
Bourgeois, F1
Weinberg, HD1
Melton, D1
Cohen, R1
de La Rocque, F1
Boucherat, M1
Bedbeder, P1
Bouhanna, CA1
Geslin, P1
Peynegre, R1
Reinert, P1
Bégué, P1
Broussin, B1
Quinet, B1
Garabedian, N1
Sounthavong, JP1
Rivière, F1
Leonetti, JP1
Stankiewicz, JA1
Rodríguez, RS1
Sánchez-Sánchez, C1
de la Torre-González, C1
Gonzalez, C1
Arnold, JE1
Woody, EA1
Erhardt, JB1
Pratt, SR1
Getts, A1
Kueser, TJ1
Kolmer, JW1
Sachs, M1
Kulik, JA1
Carlino, P1
Lampe, RM1
Weir, MR1
Varsano, I1
Volovitz, B1
Mimouni, F1
Rodriguez, WJ1
Sait, T1
Khan, WN1
Chhabra, OP1
Chang, MJ1
Reddy, S1
Marks, LA1
Gold, AJ1
Perrin, JM1
Charney, E1
MacWhinney, JB1
McInerny, TK1
Miller, RL1
Nazarian, LF1
Roddey, OF1
Earle, R1
Haggerty, R1
Halsted, C2
Lepow, ML2
Balassanian, N2
Emmerich, J2
Wolinsky, E2
Bass, JW3
Coen, SH1
Corless, JD2
Mamunes, P2
Bloom, BS1
Cashman, TM1
Frostad, AL1
Yamaoka, RM1
Schooler, RA1
Dierdorff, EP1
Cohen, SH1
McLellan, MS1
Strong, JP1
Williams, PM1
Baker, RD1
Yamamoto, K1

Reviews

3 reviews available for sulfisoxazole and Otitis Media

ArticleYear
Otitis media prevention: non-vaccine prophylaxis.
    Vaccine, 2000, Dec-08, Volume: 19 Suppl 1

    Topics: Adenoidectomy; Amoxicillin; Antibiotic Prophylaxis; Child; Child, Preschool; Clinical Trials as Topi

2000
Antimicrobial prophylaxis for recurrent otitis media.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1988, Volume: 99, Issue:1

    Topics: Acute Disease; Ampicillin; Anti-Bacterial Agents; Child; Child, Preschool; Clinical Trials as Topic;

1988
[Bacteriology and response to treatment with erythromycin-sulfisoxazole in children with acute otitis media].
    Boletin medico del Hospital Infantil de Mexico, 1987, Volume: 44, Issue:12

    Topics: Acute Disease; Child; Child, Preschool; Drug Combinations; Erythromycin; Female; Humans; Infant; Inf

1987

Trials

18 trials available for sulfisoxazole and Otitis Media

ArticleYear
Adenoidectomy versus chemoprophylaxis and placebo for recurrent acute otitis media in children aged under 2 years: randomised controlled trial.
    BMJ (Clinical research ed.), 2004, Feb-28, Volume: 328, Issue:7438

    Topics: Adenoidectomy; Anti-Infective Agents; Double-Blind Method; Female; Humans; Infant; Male; Middle Ear

2004
Sulfisoxazole chemoprophylaxis for frequent otitis media.
    Pediatrics, 1983, Volume: 71, Issue:4

    Topics: Acoustic Impedance Tests; Child, Preschool; Double-Blind Method; Eustachian Tube; Female; Haemophilu

1983
Serous otitis media. A double-blind trial with sulfisoxazole.
    Missouri medicine, 1982, Volume: 79, Issue:9

    Topics: Audiometry, Pure-Tone; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Femal

1982
Prevention and treatment of serous otitis media with an oral antihistamine. A double-blind study in pediatric practice.
    Clinical pediatrics, 1980, Volume: 19, Issue:5

    Topics: Adolescent; Ampicillin; Brompheniramine; Child; Child, Preschool; Double-Blind Method; Drug Therapy,

1980
Prophylaxis with amoxicillin or sulfisoxazole for otitis media: effect on the recovery of penicillin-resistant bacteria from children.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:1

    Topics: Amoxicillin; Bacteria; Bacteria, Aerobic; Bacteria, Anaerobic; Child; Child, Preschool; Female; Huma

1996
[An open randomized trial, Pediazole versus cefaclor in the treatment of acute otitis media in children].
    Annales de pediatrie, 1991, Volume: 38, Issue:2

    Topics: Acute Disease; Anti-Bacterial Agents; Cefaclor; Child; Child, Preschool; Drug Combinations; Erythrom

1991
[Acute otitis media in children: a randomized and open clinical trial of the efficacy of 2 major antibiotics (erythromycin ethylsuccinate/acetyl sulfafurazole vs amoxicillin/clavulanic acid)].
    Annales de pediatrie, 1990, Volume: 37, Issue:2

    Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Ch

1990
Antimicrobial prophylaxis for recurrent otitis media.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1988, Volume: 99, Issue:1

    Topics: Acute Disease; Ampicillin; Anti-Bacterial Agents; Child; Child, Preschool; Clinical Trials as Topic;

1988
Prevention of recurrent acute otitis media: chemoprophylaxis versus tympanostomy tubes.
    The Laryngoscope, 1986, Volume: 96, Issue:12

    Topics: Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Middl

1986
The effect of verbal commitment and treatment choice on medication compliance in a pediatric setting.
    Journal of behavioral medicine, 1987, Volume: 10, Issue:4

    Topics: Adolescent; Amoxicillin; Child; Child, Preschool; Choice Behavior; Drug Combinations; Erythromycin;

1987
Sulfisoxazole prophylaxis of middle ear effusion and recurrent acute otitis media.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:6

    Topics: Acute Disease; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infa

1985
Erythromycin-sulfisoxazole vs amoxicillin in the treatment of acute otitis media in children. A double-blind, multiple-dose comparative study.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:8

    Topics: Acute Disease; Amoxicillin; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Co

1985
Sulfisoxazole as chemoprophylaxis for recurrent otitis media. A double-blind crossover study in pediatric practice.
    The New England journal of medicine, 1974, Sep-26, Volume: 291, Issue:13

    Topics: Acute Disease; Administration, Oral; Child; Child, Preschool; Clinical Trials as Topic; Cooperative

1974
Myringotomy in acute otitis media. A controlled study.
    JAMA, 1966, Sep-12, Volume: 197, Issue:11

    Topics: Audiometry; Bacteria; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Myringoplasty; Nasal

1966
Otitis media. Clinical observations, microbiology, and evaluation of therapy.
    American journal of diseases of children (1960), 1968, Volume: 115, Issue:5

    Topics: Ampicillin; Bacteriological Techniques; Child, Preschool; Clinical Trials as Topic; Haemophilus infl

1968
Otitis media: microbiology and evaluation of therapy.
    Annals of the New York Academy of Sciences, 1967, Sep-27, Volume: 145, Issue:2

    Topics: Ampicillin; Bacteriological Techniques; Child; Child, Preschool; Clinical Trials as Topic; Culture M

1967
Ampicillin trihydrate in the treatment of acute otitis media in children.
    Annals of the New York Academy of Sciences, 1967, Sep-27, Volume: 145, Issue:2

    Topics: Acute Disease; Ampicillin; Bacteria; Child; Child, Preschool; Clinical Trials as Topic; Diaper Rash;

1967
Ampicillin compared to other antimicrobials in acute otitis media.
    JAMA, 1967, Nov-20, Volume: 202, Issue:8

    Topics: Ampicillin; Anti-Infective Agents; Child; Child, Preschool; Humans; Infant; Otitis Media; Oxytetracy

1967

Other Studies

24 other studies available for sulfisoxazole and Otitis Media

ArticleYear
[Bacteriological studies on tympanoplasty. II. Sensivity disc test for antibiotics of bacteria].
    Nihon Jibiinkoka Gakkai kaiho, 1962, Volume: 65

    Topics: Anti-Bacterial Agents; Bacteria; Chloramphenicol; Chlortetracycline; Drug Resistance; Drug Resistanc

1962
Experimental inclusion conjunctivitis in man. 3. Keratitis and other complications.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1967, Volume: 78, Issue:3

    Topics: Conjunctivitis, Inclusion; Corneal Ulcer; Diagnosis, Differential; Humans; Iritis; Otitis Media; Sul

1967
Sulfisoxazole chemoprophylaxis and recurrent otitis media.
    The Western journal of medicine, 1984, Volume: 140, Issue:1

    Topics: Child, Preschool; Drug Evaluation; Female; Humans; Infant; Infant, Newborn; Male; Otitis Media; Recu

1984
Sulfisoxazole prophylaxis for otitis questioned.
    Pediatrics, 1983, Volume: 72, Issue:4

    Topics: Child; Humans; Otitis Media; Recurrence; Statistics as Topic; Sulfisoxazole

1983
Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media.
    The Journal of infectious diseases, 1982, Volume: 145, Issue:6

    Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Child; Child, Preschool; Drug Therapy, Combination; Ea

1982
Sulfisoxazole as chemoprophylaxis for recurrent otitis media.
    Clinical pediatrics, 1981, Volume: 20, Issue:5

    Topics: Child; Humans; Otitis Media; Recurrence; Sulfisoxazole

1981
Prophylaxis of otitis media.
    Pediatrics, 1981, Volume: 67, Issue:4

    Topics: Child; Humans; Otitis Media; Penicillin G; Sulfisoxazole

1981
Intranasal beclomethasone in the treatment of middle ear effusion: a pilot study.
    Annals of allergy, 1980, Volume: 45, Issue:5

    Topics: Administration, Intranasal; Beclomethasone; Child; Child, Preschool; Drug Therapy, Combination; Fema

1980
[Treatment of acute otitis media].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1995, Volume: 2, Issue:1

    Topics: Acute Disease; Amoxicillin; Child; Child, Preschool; Clavulanic Acids; Drug Combinations; Erythromyc

1995
Bactericidal activity of erythromycin associated with sulphisoxazole against the infectious agents most frequently responsible for acute infantile otitis media.
    The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:4

    Topics: Bacteria; Child; Drug Therapy, Combination; Erythromycin; Haemophilus influenzae; Humans; Moraxella

1994
The susceptibility of Haemophilus influenzae middle ear and sinus isolates to sulphisoxazole.
    The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:2

    Topics: Child, Preschool; Haemophilus influenzae; Humans; Infant; Infant, Newborn; Microbial Sensitivity Tes

1994
Otitis media-related antibiotic prescribing patterns, outcomes, and expenditures in a pediatric medicaid population.
    Pediatrics, 1997, Volume: 100, Issue:4

    Topics: Acute Disease; Adolescent; Amoxicillin; Anti-Bacterial Agents; Cephalosporins; Child; Child, Prescho

1997
Round table discussion.
    Connecticut medicine, 1998, Volume: 62, Issue:1

    Topics: Amoxicillin; Child, Preschool; Common Cold; Dose-Response Relationship, Drug; Drug Resistance, Micro

1998
Opening Pandora's box.
    The Journal of pediatrics, 1977, Volume: 91, Issue:1

    Topics: Drug and Narcotic Control; Drug Combinations; Haemophilus Infections; Humans; Otitis Media; Penicill

1977
Treatment of acute otitis media.
    The Medical letter on drugs and therapeutics, 1975, Jun-20, Volume: 17, Issue:13

    Topics: Adult; Amoxicillin; Ampicillin; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy,

1975
The prevention of recurrent otitis media.
    Pediatrics, 1977, Volume: 59, Issue:3

    Topics: Child; Humans; Otitis Media; Recurrence; Sulfisoxazole

1977
In-vitro bactericidal activity of four oral antibiotics against pathogens responsible for acute otitis media in children.
    The Journal of hospital infection, 1992, Volume: 22 Suppl A

    Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ce

1992
Treatment of otitis media twice daily for five days.
    Clinical pediatrics, 1991, Volume: 30, Issue:6

    Topics: Adolescent; Amoxicillin; Anti-Infective Agents; Child; Child, Preschool; Drug Combinations; Erythrom

1991
Choosing antimicrobial therapy for otitis media.
    The Nurse practitioner, 1991, Volume: 16, Issue:3

    Topics: Amoxicillin; Anti-Infective Agents; Cefaclor; Drug Combinations; Erythromycin; Humans; Otitis Media;

1991
Erythromycin prophylaxis for recurrent otitis media.
    Clinical pediatrics, 1986, Volume: 25, Issue:10

    Topics: Erythromycin; Female; Follow-Up Studies; Haemophilus Infections; Humans; Male; Middle Ear Ventilatio

1986
Letter: Management of recurrent otitis media.
    The New England journal of medicine, 1974, Dec-19, Volume: 291, Issue:25

    Topics: Adenoidectomy; Humans; Otitis Media; Recurrence; Sulfisoxazole; Tympanic Membrane

1974
Antimicrobials in the treatment of acute otitis media. A second clinical trial.
    American journal of diseases of children (1960), 1973, Volume: 125, Issue:3

    Topics: Acute Disease; Administration, Oral; Adolescent; Age Factors; Ampicillin; Child; Child, Preschool; C

1973
Middle ear mycosis in a premature infant. Clinicopathologic study of a case.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1965, Volume: 82, Issue:6

    Topics: Adolescent; Chloramphenicol; Female; Humans; Hydrocortisone; Infant, Newborn; Infant, Premature, Dis

1965
[Drug infiltration into the granulation tissues of chronic otitis media].
    Jibi inkoka Otolaryngology, 1965, Volume: 37, Issue:11

    Topics: Humans; Otitis Media; Sulfisoxazole

1965