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sulfisoxazole and Nephrotic Syndrome

sulfisoxazole has been researched along with Nephrotic Syndrome in 6 studies

Sulfisoxazole: A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.
sulfisoxazole : A sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of gram-negative and gram-positive organisms.

Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

Research Excerpts

ExcerptRelevanceReference
"We have previously suggested that albumin in tubule fluid at concentrations found in the nephrotic syndrome (NS) binds furosemide, thereby diminishing diuretic effect."3.68Binding inhibitors restore furosemide potency in tubule fluid containing albumin. ( Brater, DC; Kirchner, KA; Voelker, JR, 1991)
"The extent and nature of furosemide (F) binding to human albumin (HA) and to the plasma of 6 children with nephrotic syndrome were studied by equilibrium dialysis at 37 degrees C and pH 7."3.65Furosemide binding to human albumin and plasma of nephrotic children. ( Prandota, J; Pruitt, AW, 1975)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
RIEGEL, C1
HAVRE, DC1
Agarwal, R1
Gorski, JC1
Sundblad, K1
Brater, DC2
Prandota, J1
Pruitt, AW1
Kirchner, KA1
Voelker, JR1
Kottová, V1

Trials

1 trial available for sulfisoxazole and Nephrotic Syndrome

ArticleYear
Urinary protein binding does not affect response to furosemide in patients with nephrotic syndrome.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:6

    Topics: Adult; Anti-Infective Agents; Area Under Curve; Chromatography, High Pressure Liquid; Cross-Over Stu

2000

Other Studies

5 other studies available for sulfisoxazole and Nephrotic Syndrome

ArticleYear
THE NEPHROTIC SYNDROME DURING PREGNANCY.
    Delaware medical journal, 1964, Volume: 36

    Topics: Biopsy; Black People; Cystitis; Female; Fetus; Glomerulonephritis; Humans; Infant; Infant, Premature

1964
CATARACTS IN CHILDREN ON LONG-TERM CORTICOSTEROID THERAPY.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1965, Volume: 73

    Topics: Adolescent; Adrenal Cortex Hormones; Cataract; Child; Chloroquine; Cyclophosphamide; Drug Therapy; F

1965
Furosemide binding to human albumin and plasma of nephrotic children.
    Clinical pharmacology and therapeutics, 1975, Volume: 17, Issue:2

    Topics: Acetazolamide; Aspirin; Child; Diazoxide; Dose-Response Relationship, Drug; Female; Furosemide; Huma

1975
Binding inhibitors restore furosemide potency in tubule fluid containing albumin.
    Kidney international, 1991, Volume: 40, Issue:3

    Topics: Albumins; Animals; Binding Sites; Binding, Competitive; Body Fluids; Dansyl Compounds; Drug Toleranc

1991
[Experience with pyelonephritis during past 10 years].
    Ceskoslovenska pediatrie, 1971, Volume: 26, Issue:3

    Topics: Adolescent; Bacteriuria; Child; Diagnosis, Differential; Female; Humans; Male; Microbial Sensitivity

1971