sulfisoxazole has been researched along with Middle Ear Effusion in 11 studies
Sulfisoxazole: A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.
sulfisoxazole : A sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of gram-negative and gram-positive organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We randomly assigned children with otitis media with effusion to receive either erythromycin-sulfisoxazole, cefaclor, amoxicillin or placebo for a 2-week period, primarily to determine whether either erythromycin-sulfisoxazole or cefaclor would have greater short term efficacy than that found previously for amoxicillin, and secondarily to supplement earlier data on outcomes in placebo-treated subjects." | 9.07 | Comparative efficacy of erythromycin-sulfisoxazole, cefaclor, amoxicillin or placebo for otitis media with effusion in children. ( Bluestone, CD; Mandel, EM; Nozza, RJ; Paradise, JL; Rockette, HE, 1991) |
| "Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media." | 7.66 | Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982) |
| "We randomly assigned children with otitis media with effusion to receive either erythromycin-sulfisoxazole, cefaclor, amoxicillin or placebo for a 2-week period, primarily to determine whether either erythromycin-sulfisoxazole or cefaclor would have greater short term efficacy than that found previously for amoxicillin, and secondarily to supplement earlier data on outcomes in placebo-treated subjects." | 5.07 | Comparative efficacy of erythromycin-sulfisoxazole, cefaclor, amoxicillin or placebo for otitis media with effusion in children. ( Bluestone, CD; Mandel, EM; Nozza, RJ; Paradise, JL; Rockette, HE, 1991) |
| "5 to 7 years) who met the usual indications for surgery (long-standing [greater than 3 months] OME and conductive hearing loss) were randomly assigned to "medical" treatment (sulfisoxazole 75 mg/kg per day for 6 months) or "surgical" treatment (bilateral insertion of VTs)." | 5.07 | Randomized, controlled trial comparing long-term sulfonamide therapy to ventilation tubes for otitis media with effusion. ( Bernard, PA; Durieux-Smith, A; Feldman, W; Stenstrom, RJ, 1991) |
| "Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media." | 3.66 | Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982) |
| "However, children with a history of serous otitis media did significantly better on placebo than did those on antihistamine, and children without a history of serous otitis media did significantly better on antihistamine than did those on placebo." | 2.65 | Prevention and treatment of serous otitis media with an oral antihistamine. A double-blind study in pediatric practice. ( Cunningham, D; Hengerer, A; Hoekelman, RA; Klein, SW; Olson, AL; Perrin, J; Roghmann, KJ, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Castro, FJ | 1 |
| Jaeger, RW | 1 |
| Martin, L | 1 |
| Temeck, JW | 1 |
| Tournour, B | 1 |
| Klein, SW | 1 |
| Olson, AL | 1 |
| Perrin, J | 1 |
| Cunningham, D | 1 |
| Hengerer, A | 1 |
| Hoekelman, RA | 1 |
| Roghmann, KJ | 1 |
| Krause, PJ | 1 |
| Owens, NJ | 1 |
| Nightingale, CH | 1 |
| Klimek, JJ | 1 |
| Lehmann, WB | 1 |
| Quintiliani, R | 1 |
| Teele, DW | 1 |
| Klein, JO | 1 |
| Word, BM | 1 |
| Rosner, BA | 1 |
| Starobin, S | 1 |
| Earle, R | 1 |
| Ertel, CS | 1 |
| Fisch, G | 1 |
| Michaels, R | 1 |
| Heppen, R | 1 |
| Strause, NP | 1 |
| Mandel, EM | 1 |
| Rockette, HE | 1 |
| Paradise, JL | 1 |
| Bluestone, CD | 1 |
| Nozza, RJ | 1 |
| Bernard, PA | 1 |
| Stenstrom, RJ | 1 |
| Feldman, W | 1 |
| Durieux-Smith, A | 1 |
| Gates, GA | 1 |
| Wachtendorf, C | 1 |
| Holt, GR | 1 |
| Hearne, EM | 1 |
| Leonetti, JP | 1 |
| Stankiewicz, JA | 1 |
| Bergeron, MG | 1 |
| Ahronheim, G | 1 |
| Richard, JE | 1 |
| Riding, K | 1 |
| Cron, C | 1 |
| Bryer, D | 1 |
| Macdonald, N | 1 |
| Bouchard, M | 1 |
| Young, J | 1 |
| Dempsey, EE | 1 |
| Corwin, MJ | 1 |
| Weiner, LB | 1 |
| Daniels, D | 1 |
| Varsano, I | 1 |
| Volovitz, B | 1 |
| Mimouni, F | 1 |
1 review available for sulfisoxazole and Middle Ear Effusion
| Article | Year |
|---|---|
Antimicrobial prophylaxis for recurrent otitis media.
Topics: Acute Disease; Ampicillin; Anti-Bacterial Agents; Child; Child, Preschool; Clinical Trials as Topic; | 1988 |
10 trials available for sulfisoxazole and Middle Ear Effusion
| Article | Year |
|---|---|
Serous otitis media. A double-blind trial with sulfisoxazole.
Topics: Audiometry, Pure-Tone; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Femal | 1982 |
Prevention and treatment of serous otitis media with an oral antihistamine. A double-blind study in pediatric practice.
Topics: Adolescent; Ampicillin; Brompheniramine; Child; Child, Preschool; Double-Blind Method; Drug Therapy, | 1980 |
Antimicrobial prophylaxis for infants at risk for recurrent acute otitis media.
Topics: Acute Disease; Amoxicillin; Antibiotic Prophylaxis; Cohort Studies; Double-Blind Method; Drug Erupti | 2000 |
Comparative efficacy of erythromycin-sulfisoxazole, cefaclor, amoxicillin or placebo for otitis media with effusion in children.
Topics: Amoxicillin; Anti-Infective Agents; Cefaclor; Child; Child, Preschool; Drug Combinations; Erythromyc | 1991 |
Randomized, controlled trial comparing long-term sulfonamide therapy to ventilation tubes for otitis media with effusion.
Topics: Audiometry, Pure-Tone; Auditory Threshold; Child; Child, Preschool; Female; Hearing Loss, Conductive | 1991 |
Medical treatment of chronic otitis media with effusion (secretory otitis media).
Topics: Age Factors; Anti-Infective Agents; Child; Child, Preschool; Chronic Disease; Clinical Trials as Top | 1986 |
Antimicrobial prophylaxis for recurrent otitis media.
Topics: Acute Disease; Ampicillin; Anti-Bacterial Agents; Child; Child, Preschool; Clinical Trials as Topic; | 1988 |
Comparative efficacies of erythromycin-sulfisoxazole and cefaclor in acute otitis media: a double blind randomized trial.
Topics: Acute Disease; Adolescent; Ampicillin; Anti-Bacterial Agents; Cefaclor; Cephalexin; Child; Child, Pr | 1987 |
Efficacy of oral antibiotics for the treatment of persistent otitis media with effusion.
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Drug Therapy, Combination; Erythromycin; | 1986 |
Sulfisoxazole prophylaxis of middle ear effusion and recurrent acute otitis media.
Topics: Acute Disease; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infa | 1985 |
1 other study available for sulfisoxazole and Middle Ear Effusion
| Article | Year |
|---|---|
Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media.
Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Child; Child, Preschool; Drug Therapy, Combination; Ea | 1982 |