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sulfinpyrazone and Pheochromocytoma

sulfinpyrazone has been researched along with Pheochromocytoma in 1 studies

Sulfinpyrazone: A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
"The neuroblastoma-like cell line N2A and the pheochromocytoma-like cell line PC12 excrete about 20-25% of the intracellular fluorescent Ca2+ indicator fura-2 during 10 min of incubation at 37 degrees C."3.67Inhibitors of membrane transport system for organic anions block fura-2 excretion from PC12 and N2A cells. ( Di Virgilio, F; Fasolato, C; Steinberg, TH, 1988)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Di Virgilio, F1
Fasolato, C1
Steinberg, TH1

Other Studies

1 other study available for sulfinpyrazone and Pheochromocytoma

ArticleYear
Inhibitors of membrane transport system for organic anions block fura-2 excretion from PC12 and N2A cells.
    The Biochemical journal, 1988, Dec-15, Volume: 256, Issue:3

    Topics: Animals; Benzofurans; Biological Transport; Calcium; Cell Line; Cell Membrane Permeability; Fluoresc

1988