sulfinpyrazone has been researched along with Ischemic Attack, Transient in 52 studies
Sulfinpyrazone: A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aspirin has been convincingly shown to reduce stroke and death in men with transient ischemic attacks (it may possibly be beneficial to women also), myocardial infarction and death in patients with unstable angina, thromboembolic complications associated with artificial heart valves in patients receiving oral anticoagulants (although gastrointestinal bleeding is prohibitive with this combination), and thrombotic occlusion of silicone rubber arteriovenous cannulae in uremic patients undergoing hemodialysis." | 6.15 | Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis. ( Harker, LA, 1986) |
| "Data from the Aspirin in Transient Ischemic Attack (AITIA) study, an ongoing study of two platelet antiaggregant drugs, and other published therapeutic trials were reviewed to determine whether the severity of stroke is reduced in patients taking platelet antiaggregants." | 3.75 | Does platelet antiaggregant therapy lessen the severity of stroke? ( Fields, WS; Gary, H; Grotta, JC; Lemak, NA; Vital, D, 1985) |
| "The incidence of recurrences was much greater in the initial 4 months but there was no difference between the 2 treatments." | 2.65 | Transient cerebral ischaemic attacks--management and prognosis. ( Carmalt, M; Cockel, R; Green, I; Low-Beer, T; Roden, S, 1981) |
| "Dipyridamole can inhibit both platelet adhesion and aggregation by raising the platelet cyclic AMP level through phosphodiesterase inhibition." | 2.37 | Aspirin and other platelet-aggregation inhibiting drugs. ( Gallus, AS, 1985) |
| "The authors report 22 cases of transient ischemic attacks (TIA's) manifested by amaurosis fugax or hemiparesis or paresthesia of less than 24 hours' duration." | 1.26 | Transient ischemic attacks due to increased platelet aggregation and adhesiveness. Ultrastructural and functional correlation. ( al-Mefty, O; Marano, G; Nugent, GR; Raiaraman, S; Rodman, N, 1979) |
| "Sulfinpyrazone treatment of patients with myocardial infarction (Killip--classification I and II), starting 25--35 days after the acute myocardial infarction, reduces cardiac mortality and incidence of sudden death for a period of two years." | 1.26 | [Action mechanism and clinical indications for thrombocyte aggregation inhibitors]. ( Oelz, O, 1979) |
| "and sulfinpyrazone have been tested in several large scale clinical trials." | 1.26 | [Antiplatelet drugs (author's transl)]. ( Dechavanne, M; Follea, G; Trzeciak, MC, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 50 (96.15) | 18.7374 |
| 1990's | 2 (3.85) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ritter, JM | 1 |
| Genton, E | 2 |
| Hinton, RC | 1 |
| Wilkerson, RJ | 1 |
| Liem, PH | 1 |
| Carter, WJ | 1 |
| Bousser, MG | 1 |
| Lechner, H | 1 |
| Ott, E | 1 |
| Bertha, G | 1 |
| Ramirez-Lassepas, M | 1 |
| Eichner, ER | 1 |
| Cain, TD | 1 |
| Wood, JS | 1 |
| Beard, OW | 1 |
| Easton, JD | 1 |
| Hart, RG | 1 |
| Sherman, DG | 1 |
| Kaste, M | 1 |
| Saavedra, JC | 1 |
| Vergara, F | 1 |
| Whisnant, JP | 2 |
| Barnett, HJ | 6 |
| Gent, M | 4 |
| Sackett, DL | 3 |
| Taylor, DW | 3 |
| Friedman, LM | 1 |
| Roden, S | 1 |
| Low-Beer, T | 1 |
| Carmalt, M | 1 |
| Cockel, R | 1 |
| Green, I | 1 |
| Warlow, CP | 1 |
| Laiwah, AC | 1 |
| Sørensen, PS | 1 |
| Marquardsen, J | 1 |
| Owen, J | 1 |
| Seidenfeld, AM | 1 |
| Glynn, MF | 1 |
| Deykin, D | 1 |
| Gurewich, V | 1 |
| Harker, L | 1 |
| Hirsch, J | 1 |
| Sandok, BA | 1 |
| Furlan, AJ | 1 |
| Sundt, TM | 1 |
| Kurtzke, JF | 1 |
| Armitage, P | 1 |
| Hirsh, J | 2 |
| Mitchell, JR | 1 |
| Ostendorf, P | 1 |
| al-Mefty, O | 1 |
| Marano, G | 1 |
| Raiaraman, S | 1 |
| Nugent, GR | 1 |
| Rodman, N | 1 |
| Oelz, O | 1 |
| Dechavanne, M | 1 |
| Follea, G | 1 |
| Trzeciak, MC | 1 |
| Regli, F | 1 |
| Michaud, PA | 1 |
| McDonald, JW | 1 |
| Stuart, RK | 1 |
| Mustard, JF | 1 |
| Packham, MA | 1 |
| Kinlough-Rathbone, RL | 1 |
| Harker, LA | 2 |
| Robertson, JT | 1 |
| Dugdale, M | 1 |
| Salky, N | 1 |
| Robinson, H | 1 |
| Kendall, MJ | 1 |
| Stachenko, SJ | 1 |
| Bravo, G | 1 |
| Côté, R | 1 |
| Boucher, J | 1 |
| Battista, RN | 1 |
| Inzitari, D | 1 |
| Fratiglioni, L | 1 |
| Baldereschi, M | 1 |
| Candelise, L | 1 |
| Anzalone, N | 1 |
| Bonatti, ML | 1 |
| Prencipe, M | 1 |
| Gandolfo, C | 1 |
| Mamoli, A | 1 |
| Rasura, M | 1 |
| Sze, PC | 1 |
| Reitman, D | 1 |
| Pincus, MM | 1 |
| Sacks, HS | 1 |
| Chalmers, TC | 1 |
| Gallus, AS | 1 |
| Grotta, JC | 1 |
| Lemak, NA | 1 |
| Gary, H | 1 |
| Fields, WS | 1 |
| Vital, D | 1 |
| Sherry, S | 1 |
| Evans, G | 1 |
| Millikan, CH | 1 |
15 reviews available for sulfinpyrazone and Ischemic Attack, Transient
| Article | Year |
|---|---|
Current therapy of cerebrovascular disease.
Topics: Adult; Aged; Anticoagulants; Aspirin; Cerebrovascular Disorders; Dipyridamole; Female; Humans; Ische | 1984 |
Therapeutical aspects of cerebrovascular disease.
Topics: Aspirin; Blood Coagulation; Cerebrovascular Disorders; Clofibrate; Dipyridamole; Erythrocyte Aggrega | 1983 |
Platelet inhibitors for TIAs. A review of prospective drug trial results.
Topics: Aged; Aspirin; Clofibrate; Dipyridamole; Drug Therapy, Combination; Female; Humans; Ischemic Attack, | 1984 |
Platelets, carotids, and coronaries. Critique on antithrombotic role of antiplatelet agents, exercise, and certain diets.
Topics: Angina Pectoris; Arteriosclerosis; Aspirin; Blood Platelets; Blood Vessels; Carotid Artery Thrombosi | 1984 |
Medical Grand Rounds: extracranial carotid artery disease.
Topics: Adolescent; Adult; Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Auscultation; Carotid Art | 1980 |
Cerebrovascular disease.
Topics: Anticoagulants; Antifibrinolytic Agents; Aspirin; Blood Platelets; Cerebrovascular Disorders; Fibrin | 1981 |
The pathophysiology of transient cerebral ischemic attacks.
Topics: Arteriosclerosis; Aspirin; Carotid Arteries; Cerebrovascular Disorders; Cholesterol; Embolism; Endoc | 1979 |
Platelet inhibitors in the treatment of thrombosis.
Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Clinical Trials as Topic; Clof | 1978 |
Platelet-inhibiting drugs in the prevention of clinical thrombotic disease (first of three parts).
Topics: Animals; Antidepressive Agents, Tricyclic; Aspirin; Blindness; Blood Platelets; Cerebrovascular Diso | 1975 |
Aspirin in transient ischemic attacks and minor stroke: a meta-analysis.
Topics: Adult; Aspirin; Cerebrovascular Disorders; Dipyridamole; Drug Therapy, Combination; Female; Humans; | 1991 |
[Study Group: "Evaluation of the efficacy of therapeutic treatments in cerebrovascular diseases"].
Topics: Aged; Anticoagulants; Aspirin; Cerebrovascular Disorders; Dipyridamole; Double-Blind Method; Female; | 1990 |
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical | 1986 |
Aspirin and other platelet-aggregation inhibiting drugs.
Topics: Aspirin; Blood Platelets; Coronary Artery Bypass; Coronary Disease; Dipyridamole; Female; Heart Valv | 1985 |
Does platelet antiaggregant therapy lessen the severity of stroke?
Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Double-Blind Method; Humans; Ischemic | 1985 |
Clinical aspects of antiplatelet therapy.
Topics: Angina Pectoris; Aspirin; Blood Coagulation Disorders; Clinical Trials as Topic; Dipyridamole; Femal | 1985 |
25 trials available for sulfinpyrazone and Ischemic Attack, Transient
| Article | Year |
|---|---|
A perspective on platelet-suppressant drug treatment in coronary artery and cerebrovascular disease.
Topics: Adrenergic beta-Antagonists; Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Cerebrovascula | 1980 |
[Role of antiplatelet agents in the prevention of cerebral ischemic accidents].
Topics: Adult; Aged; Anticoagulants; Arteriosclerosis; Aspirin; Blood Platelets; Clinical Trials as Topic; C | 1983 |
Medical Grand Rounds: extracranial carotid artery disease.
Topics: Adolescent; Adult; Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Auscultation; Carotid Art | 1980 |
The Canadian trial of aspirin and sulfinpyrazone in threatened stroke.
Topics: Aged; Anticoagulants; Aspirin; Blood Platelets; Canada; Cerebrovascular Disorders; Clinical Trials a | 1980 |
Randomized trial of therapy with platelet antiaggregants for threatened stroke. 2: Observations on the pathogenesis and natural history of threatened stroke.
Topics: Adolescent; Adult; Aged; Carotid Artery Thrombosis; Carotid Artery, Internal; Cerebrovascular Disord | 1980 |
Summary of design features: clinical trials of platelet-active drugs in cerebrovascular disease.
Topics: Aspirin; Blood Platelets; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; | 1980 |
A randomized trial of aspirin and sulfinpyrazone in patients with threatened stroke. Results and methodologic issues.
Topics: Actuarial Analysis; Aspirin; Canada; Cerebrovascular Disorders; Clinical Trials as Topic; Death, Sud | 1980 |
Transient cerebral ischaemic attacks--management and prognosis.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ischemic Attack, Transient; Mal | 1981 |
A randomized trial of aspirin and sulfinpyrazone in threatened stroke.
Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; | 1978 |
Guidelines for the management of transient ischemic attacks.
Topics: Anticoagulants; Aspirin; Blood Platelets; Carotid Arteries; Clinical Trials as Topic; Dipyridamole; | 1978 |
Aspirin to prevent a stroke?
Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Female; Humans; Ischemic Attack, Trans | 1978 |
Controversy in neurology: the Canadian study on TIA and aspirin. A critique of the Canadian TIA study.
Topics: Aspirin; Canada; Clinical Trials as Topic; Double-Blind Method; Humans; Ischemic Attack, Transient; | 1979 |
Controversy in neurology: the Canadian study on TIA and aspirin. A critique of the Canadian TIA study. Reply.
Topics: Aspirin; Canada; Clinical Trials as Topic; Double-Blind Method; Humans; Ischemic Attack, Transient; | 1979 |
Controversy in the interpretation of clinical trials.
Topics: Aspirin; Canada; Clinical Trials as Topic; Double-Blind Method; Humans; Ischemic Attack, Transient; | 1979 |
Platelet inhibitors in the treatment of thrombosis.
Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Clinical Trials as Topic; Clof | 1978 |
Does aspirin prevent stroke?
Topics: Anticoagulants; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic; Dipyr | 1979 |
The role of platelets in transient ischemic attacks and cerebral vascular accidents.
Topics: Aspirin; Blood Platelets; Cerebrovascular Disorders; Female; Humans; Ischemic Attack, Transient; Mal | 1978 |
Platelet-inhibiting drugs in the prevention of clinical thrombotic disease (first of three parts).
Topics: Animals; Antidepressive Agents, Tricyclic; Aspirin; Blindness; Blood Platelets; Cerebrovascular Diso | 1975 |
Proceedings: The effect of a platelet inhibiting drug (sulfinpyrazone) in the therapy of patients with transient ischemic attacks (Tia's) and minor strokes.
Topics: Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic; Humans; Ischemic Attack, Trans | 1975 |
[Study Group: "Evaluation of the efficacy of therapeutic treatments in cerebrovascular diseases"].
Topics: Aged; Anticoagulants; Aspirin; Cerebrovascular Disorders; Dipyridamole; Double-Blind Method; Female; | 1990 |
Antiplatelet agents in the secondary prevention of stroke: meta-analysis of the randomized control trials.
Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Dipyridamole; Drug Combinations; Human | 1988 |
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical | 1986 |
Does platelet antiaggregant therapy lessen the severity of stroke?
Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Double-Blind Method; Humans; Ischemic | 1985 |
Clinical aspects of antiplatelet therapy.
Topics: Angina Pectoris; Aspirin; Blood Coagulation Disorders; Clinical Trials as Topic; Dipyridamole; Femal | 1985 |
Effect of drugs that suppress platelet surface interaction on incidence of amaurosis fugax and transient cerebral ishcemia.
Topics: Blindness; Blood Platelets; Clinical Trials as Topic; Humans; Ischemic Attack, Transient; Placebos; | 1972 |
19 other studies available for sulfinpyrazone and Ischemic Attack, Transient
| Article | Year |
|---|---|
Placebo-controlled, double-blind clinical trials can impede medical progress.
Topics: Adrenergic beta-Antagonists; Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Double-Bl | 1980 |
Treatment of cerebral ischemia.
Topics: Aspirin; Brain Ischemia; Carotid Arteries; Dicumarol; Dipyridamole; Endarterectomy; Heart Murmurs; H | 1981 |
Diagnosis and management of ischemic stroke. Part I.--Threatened stroke and its management.
Topics: Anticoagulants; Arrhythmias, Cardiac; Aspirin; Brain Ischemia; Carotid Artery Thrombosis; Cerebral A | 1983 |
[Present status of the therapy of acute cerebral transient ischemic attacks].
Topics: Acute Disease; Aspirin; Carotid Arteries; Cerebral Infarction; Drug Therapy, Combination; Endarterec | 1983 |
Transient cerebral ischaemic attacks.
Topics: Anticoagulants; Aspirin; Carotid Arteries; Carotid Artery Diseases; Diagnosis, Differential; Humans; | 1982 |
[Preventive drug therapy of transient cerebral ischemic attacks].
Topics: Anticoagulants; Aspirin; Dipyridamole; Humans; Ischemic Attack, Transient; Platelet Aggregation; Sul | 1982 |
Antiplatelet drugs after myocardial infarction.
Topics: Aspirin; Dipyridamole; Humans; Ischemic Attack, Transient; Myocardial Infarction; Platelet Aggregati | 1980 |
Amelioration of cardiac hemolytic anemia by sulfinpyrazone therapy.
Topics: Aged; Anemia, Hemolytic; Anticoagulants; Female; Heart Valve Prosthesis; Humans; Ischemic Attack, Tr | 1980 |
Aspirin and stroke prevention.
Topics: Adult; Aspirin; Cerebrovascular Disorders; Female; Humans; Ischemic Attack, Transient; Male; Risk; S | 1978 |
Treating thromboembolic disease.
Topics: Anticoagulants; Aspirin; Coronary Artery Bypass; Dipyridamole; Fibrinolytic Agents; Heart Valve Pros | 1977 |
[Therapy with anticoagulants and platelet aggregation inhibitors in extracranial vascular stenoses and occlusions].
Topics: Anticoagulants; Arterial Occlusive Diseases; Aspirin; Cerebral Infarction; Cerebrovascular Disorders | 1979 |
Transient ischemic attacks due to increased platelet aggregation and adhesiveness. Ultrastructural and functional correlation.
Topics: Adolescent; Adult; Aspirin; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Dipy | 1979 |
[Action mechanism and clinical indications for thrombocyte aggregation inhibitors].
Topics: Anticoagulants; Aspirin; Coronary Disease; Dipyridamole; Humans; Ischemic Attack, Transient; Myocard | 1979 |
[Antiplatelet drugs (author's transl)].
Topics: Aspirin; Blood Platelets; Clofibrate; Dipyridamole; Female; Humans; Hydroxychloroquine; Ischemic Att | 1979 |
[Treatment of transient ischemic attacks (author's transl)].
Topics: Angiography; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Endarterectomy; Humans; Ischemic | 1978 |
Effects of aspirin and sulfinpyrazone on platelet prostaglandin synthesis.
Topics: Aspirin; Blood Platelets; Collagen; Ischemic Attack, Transient; Kinetics; Prostaglandins; Serotonin; | 1977 |
Effect of drugs of platelets and complications of vascular disease.
Topics: Animals; Anticoagulants; Aspirin; Blood Coagulation; Blood Platelets; Clofibrate; Coronary Disease; | 1977 |
Letter: Medical management of transient ischaemic attacks.
Topics: Anti-Inflammatory Agents; Anticoagulants; Aspirin; Dipyridamole; Humans; Ischemic Attack, Transient; | 1975 |
Address of the president-elect: the indication for various methods of treatment of occlusive cerebrovascular disease.
Topics: Anticoagulants; Aspirin; Blood Pressure; Cardiac Output; Carotid Arteries; Cerebral Angiography; Cer | 1973 |