sulfinpyrazone and Gout studies

Sulfinpyrazone: A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.

Gout: Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi.

Research Excerpts

Excerpt	Relevance	Reference
"Allopurinol has been universally successful in lowering the serum uric acid concentration and uric acid excretion to normal levels, while not significantly affecting the clearance of urate or other aspects of renal function."	5.24	The treatment of gout and disorders of uric acid metabolism with allopurinol. ( Houpt, JB; Ogryzlo, MA; Urowitz, MB; Weber, HM, 1966)
" Allopurinol is more frequently used than uricosuric agents such as probenecid, and toxicity may be largely avoided by tailoring dosage schedules according to renal function."	3.77	Risks and benefits of drugs used in the management and prevention of gout. ( Conaghan, PG; Day, RO, 1994)
"We identified persons using two integrated delivery systems aged 18 years or older with a diagnosis of gout who initiated use of allopurinol, probenecid or sulfinpyrazone from 1 January 2000 to 30 June 2006."	3.75	Adherence with urate-lowering therapies for the treatment of gout. ( Andrade, SE; Briesacher, BA; Fouayzi, H; Harrold, LR; Ockene, IS; Raebel, MA; Yood, RA, 2009)
" The drug is particularly useful in patients with chronic gouty arthritis and tophi, either refractory or allergic to probenecid, sulfinpyrazone, or allopurinol."	3.65	Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone. ( Yu, TF, 1976)
"Gout is increasingly recognized as the most common form of inflammatory arthritis worldwide; however, no Canadian data on the disease burden of gout are available."	1.46	The rising prevalence and incidence of gout in British Columbia, Canada: Population-based trends from 2000 to 2012. ( Aviña-Zubieta, JA; Choi, HK; De Vera, MA; McCormick, N; Rai, SK; Sayre, EC; Shojania, K, 2017)
"Coronary heart disease is the leading cause of death in the gouty and nongouty population."	1.26	Changing trends of mortality in gout. ( Talbott, JH; Yü, T, 1980)
"The management of gout has four phases: control of inflammation, diagnostic evaluation, education of the patient, and treatment for the hyperuricemia."	1.26	Management of gout. ( Simkin, PA, 1979)
"Allopurinol has been universally successful in lowering the serum uric acid concentration and uric acid excretion to normal levels, while not significantly affecting the clearance of urate or other aspects of renal function."	1.24	The treatment of gout and disorders of uric acid metabolism with allopurinol. ( Houpt, JB; Ogryzlo, MA; Urowitz, MB; Weber, HM, 1966)

Timeframe	Studies, this research(%)	All Research%
pre-1990	115 (96.64)	18.7374
1990's	1 (0.84)	18.2507
2000's	2 (1.68)	29.6817
2010's	1 (0.84)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Rai, SK	1
Aviña-Zubieta, JA	1
McCormick, N	1
De Vera, MA	1
Shojania, K	1
Sayre, EC	1
Choi, HK	1
Harrold, LR	1
Andrade, SE	1
Briesacher, BA	1
Raebel, MA	1
Fouayzi, H	1
Yood, RA	1
Ockene, IS	1
FARN, KT	1
PERSELLIN, RH	1
SCHMID, FR	2
LEVERNIEUX, J	1
LUCEY, C	1
MUGLER, A	1
STENGER, EG	1
BORRACHERO, J	2
DEL CARMEN SANCHEZ DE BORRACHERO, M	1
CUBUKCU, OC	1
IMRE, I	1
ONEL, D	1
BERGAMINI, A	1
VENTURA, E	1
DENKO, CW	1
MENDES DE LEON, DE	1
WINDSMA, J	1
VAN DER SLUIS, I	1
ITO, H	1
OKAZAKI, M	1
AKAOKA, I	3
KOYAMA, S	1
BIANCHI, W	1
PEREIRA, OM	1
FARINA, LI	1
MOLL, K	1
CARCASSONNE, Y	1
MARSON, FG	1
AMAKO, T	1
YAMAMOTO, M	1
ODA, H	1
FUJIKI, A	1
RIVERA, JV	1
KUZELL, WC	4
GLOVER, RP	3
GIBBS, JO	2
BLAU, RA	2
TREADWELL, B	1
REAH, TG	1
RUIZ, SI	1
BUONICONTI, A	1
D AURIA, H	1
COBRA, CJ	1
GAMARSKI, J	1
BAFUTTO, MG	1
ZUPELLI, W	1
LIPSON, RL	1
SLOCUMB, CH	1
EHRENBOECK, R	1
SANCHEZMDEL, C	1
MONTERO, M	1
BERMEJILLO, F	1
SMYTHE, HA	1
OGRYZLO, MA	3
MURPHY, EA	1
MUSTARD, JF	1
GOLDFINGER, S	1
KLINENBERG, JR	3
SEEGMILLER, JE	2
RINGOIR, S	1
VELAYOS, EE	1
SMYTH, CJ	2
HILLECKE, NA	1
MELLINGHOFF, CH	1
GROSS, RH	1
Solomon, DH	1
Avorn, J	1
Levin, R	1
Brookhart, MA	1
Schulze, H	1
Gaines, LM	1
Seebach, LM	2
Palella, TD	1
Kelley, WN	4
Rodnan, GP	1
Durham, DS	1
Ibels, LS	1
Baiatova, KV	1
Obel, AO	1
Gut, JP	1
Yü, T	2
Talbott, JH	1
Conaghan, PG	1
Day, RO	1
Pallalardo, A	1
Gancitano, A	1
Schräpler, P	1
Schulz, E	1
Kleinschmidt, A	1
Emmerson, BT	1
Simkin, PA	1
Bayliss, RI	1
McCarty, DJ	2
Nishizawa, T	1
Nishida, Y	1
Masuda, T	1
Gordon, GV	1
Schumacher, HR	1
Alvsaker, JO	1
Yu, TF	4
Witwer, MW	1
Tesar, JT	1
O'Duffy, JD	1
Hunder, GG	1
Kelly, PJ	1
Sinclair, DS	1
Fox, IH	2
Erill, S	1
Laporte, J	1
Konrád, K	1
Schlapbach, P	1
Lo, B	1
Elion, GB	1
Zöllner, N	1
Gutman, AB	4
Sans Solá, L	1
Gershon, SL	1
Kersley, GD	5
Bluestone, R	2
Campion, D	1
Whitehouse, M	1
Mayr, E	1
Goldfinger, SE	1
Gottesbüren, H	1
Strohmeyer, G	1
Wyngaarden, JB	1
Yoshimura, T	1
Mikanagi, K	1
Woodbury, JF	1
Mehta, DM	1
Morse, WI	1
Fellet, AJ	1
Gerbaux, JO	1
Rodhain, J	1
Klotz, H	1
Prohaska, E	1
Salmhofer, H	1
Schmid, L	1
Houpt, JB	3
Scott, JT	1
Jackman, AE	1
Kippen, I	1
Günther, R	2
Knapp, E	2
Motawakel, AG	1
Nyfos, L	1
Michotte, JL	1
Burtonboy, G	1
Munthe, E	1
Riccitelli, ML	1
Palmer, DG	1
Highton, TC	1
Malamos, B	1
Sfikakis, P	1
Tsekos, G	1
Tasiopoulos, T	1
Herbst, M	1
Siller, K	1
Casademont, M	1
Holländer, E	1
Schwarczmann, P	1
Cottet, J	1
Urowitz, MB	2
Weber, HM	2
Goldfarb, E	1
Bartels, EC	1

Article	Year
Treatment of the gout and other forms of crystal-induced arthritis. Bulletin on the rheumatic diseases, 1982, Volume: 32, Issue:5 Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Benzbromarone; Colchicine; Gout; Go	1982
Risks and benefits of drugs used in the management and prevention of gout. Drug safety, 1994, Volume: 11, Issue:4 Topics: Adrenocorticotropic Hormone; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Doubl	1994
[Gout. Diagnosis--pathogenesis--therapy]. Fortschritte der Medizin, 1978, Mar-30, Volume: 96, Issue:12 Topics: Allopurinol; Balneology; Benzofurans; Crystallization; Diagnosis, Differential; Exercise Therapy; Gl	1978
Drug control of gout and hyperuricaemia. Drugs, 1978, Volume: 16, Issue:2 Topics: Allopurinol; Arthritis; Chronic Disease; Colchicine; Gout; Humans; Indomethacin; Naproxen; Phenylbut	1978
Pharmacologic approach to the maintenance of urate homeostasis. Nephron, 1975, Volume: 14, Issue:1 Topics: Allopurinol; Diuresis; Gout; Homeostasis; Humans; Kidney Tubules; Probenecid; Sulfinpyrazone; Uric A	1975
Observations with Rabenid in patients with locomotor disease. Therapia Hungarica (English edition), 1989, Volume: 37, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Gout; Human	1989
[Gout: diagnosis and therapy]. Therapeutische Umschau. Revue therapeutique, 1985, Volume: 42, Issue:10 Topics: Allopurinol; Colchicine; Gout; Gout Suppressants; Humans; Indomethacin; Probenecid; Sulfinpyrazone	1985
Crystal deposition joint disease. Annual review of medicine, 1974, Volume: 25 Topics: Aged; Arthritis, Rheumatoid; Chondrocalcinosis; Colchicine; Crystallization; Diphosphates; Female; G	1974
Milestones in the treatment of gout. The American journal of medicine, 1974, Volume: 56, Issue:5 Topics: Allopurinol; Colchicine; Gout; Humans; Indomethacin; Kidney Calculi; Probenecid; Sulfinpyrazone; Uri	1974
Principles of current management of primary gout. The American journal of the medical sciences, 1967, Volume: 254, Issue:6 Topics: Adult; Allopurinol; Diet Therapy; Female; Gout; Humans; Male; Middle Aged; Probenecid; Sulfinpyrazon	1967
[Antarthritics. 41]. Pharmazeutische Praxis, 1969, Volume: 12 Topics: Acute Disease; Allopurinol; Antineoplastic Agents; Benzofurans; Colchicine; Female; Gout; Humans; Ph	1969
Treatment of gout. The New England journal of medicine, 1971, Dec-02, Volume: 285, Issue:23 Topics: Adrenal Cortex Hormones; Allopurinol; Colchicine; Gout; Humans; Indomethacin; Phenylbutazone; Proben	1971
[What is certain in gout therapy?]. Der Internist, 1971, Volume: 12, Issue:12 Topics: Acute Disease; Allopurinol; Chronic Disease; Colchicine; Gout; Humans; Hydrogen-Ion Concentration; K	1971
Drug treatment of gout. Seminars in drug treatment, 1971, Volume: 1, Issue:2 Topics: Acute Disease; Allopurinol; Arthritis; Colchicine; Gout; Humans; Orotic Acid; Probenecid; Structure-	1971
Uricosuric drugs, with special reference to probenecid and sulfinpyrazone. Advances in pharmacology, 1966, Volume: 4 Topics: Gout; Humans; Male; Probenecid; Sulfinpyrazone; Uricosuric Agents	1966

Article	Year
Risks and benefits of drugs used in the management and prevention of gout. Drug safety, 1994, Volume: 11, Issue:4 Topics: Adrenocorticotropic Hormone; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Doubl	1994
Observations with Rabenid in patients with locomotor disease. Therapia Hungarica (English edition), 1989, Volume: 37, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Gout; Human	1989
The effect of allopurinol (HPP) in the treatment of gout. Arthritis and rheumatism, 1965, Volume: 8, Issue:5 Topics: Clinical Trials as Topic; Enzyme Therapy; Female; Gout; Humans; Male; Sulfinpyrazone; Xanthine Oxida	1965
Comparison of allopurinol and probenecid. Annals of the rheumatic diseases, 1966, Volume: 25, Issue:6 Suppl Topics: Allopurinol; Clinical Trials as Topic; Colchicine; Enzyme Therapy; Follow-Up Studies; Gout; Humans;	1966
Treatment of gout with allopurinol and sulphinpyrazone in combination and with allopurinol alone. Annals of the rheumatic diseases, 1966, Volume: 25, Issue:6 Suppl Topics: Acute Kidney Injury; Adult; Aged; Allopurinol; Arthritis, Rheumatoid; Clinical Trials as Topic; Duod	1966
Effect of drugs on urate binding to plasma proteins. British medical journal, 1969, Dec-06, Volume: 4, Issue:5683 Topics: Adult; Allopurinol; Arthritis; Aspirin; Blood Proteins; Chromatography, DEAE-Cellulose; Colchicine;	1969

Article	Year
The rising prevalence and incidence of gout in British Columbia, Canada: Population-based trends from 2000 to 2012. Seminars in arthritis and rheumatism, 2017, Volume: 46, Issue:4 Topics: Aged; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; British Columbia; Colchicine; Comorbidit	2017
Adherence with urate-lowering therapies for the treatment of gout. Arthritis research & therapy, 2009, Volume: 11, Issue:2 Topics: Age Factors; Allopurinol; Female; Gout; Gout Suppressants; Humans; Male; Medication Adherence; Middl	2009
Sulphinpyrazone in the treatment of gout. The Practitioner, 1961, Volume: 187 Topics: Gout; Phenylbutazone; Sulfinpyrazone	1961
The use of sulfinpyrazone in the treatment of gout. JAMA, 1961, Mar-18, Volume: 175 Topics: Gout; Phenylbutazone; Sulfinpyrazone	1961
[Observations made on the action of sulfinpyrazone in the treatment of gout after 3 years of recession]. Revue du rhumatisme et des maladies osteo-articulaires, 1961, Volume: 28 Topics: Gout; Phenylbutazone; Sulfinpyrazone	1961
[Anturan on gouty diseases]. La Semaine des hopitaux: therapeutique, 1960, Volume: 36 Topics: Gout; Phenylbutazone; Sulfinpyrazone	1960
Anturan in the treatment of gout. Irish journal of medical science, 1961, Volume: 423 Topics: Gout; Phenylbutazone; Sulfinpyrazone	1961
[Effects of sulfinpyrazone on uricemia and excretion of uric acid in 50 gouty hyperuricemic patients during diuretic thermal treatment. Comparison of its action in simple gout patients and in tophaceous gout patients]. La Presse medicale, 1961, May-20, Volume: 69 Topics: Biological Transport; Body Fluids; Diuretics; Gout; Humans; Hyperuricemia; Phenylbutazone; Sulfinpyr	1961
[A saluretic active component of the uricosuric G-28315 (anturan)]. Medicina experimentalis : International journal of experimental medicine, 1959, Volume: 1 Topics: Diuretics; Gout; Phenylbutazone; Sulfinpyrazone	1959
[Treatment of chronic gouty arthritis with Anturan (G-28315)]. Medicina, 1962, Volume: 30 Topics: Arthritis, Gouty; Chronic Disease; Gout; Phenylbutazone; Sulfinpyrazone	1962
[Anturan in the gout therapy]. Zeitschrift fur Rheumaforschung, 1961, Volume: 20 Topics: Gout; Phenylbutazone; Sulfinpyrazone	1961
[Sulfinpyrazone in juvenile polyarticular gout. Reversible obstructive tubulonephrosis as an early complication of effective uricosuric treatment]. Minerva medica, 1962, Nov-28, Volume: 53 Topics: Gout; Humans; Hyperuricemia; Kidney Diseases; Sulfinpyrazone; Sulfonamides	1962
TREATMENT OF THE PATIENT WITH GOUT. The Ohio State medical journal, 1963, Volume: 59 Topics: Chlorthalidone; Colchicine; Diagnosis; Gout; Humans; Oxyphenbutazone; Phenylbutazone; Probenecid; Py	1963
[GOUT AND ITS TREATMENT WITH SULFINPYRAZONE]. Nederlands tijdschrift voor geneeskunde, 1963, Dec-14, Volume: 107 Topics: Geriatrics; Gout; Humans; Sulfinpyrazone; Uricosuric Agents	1963
[CASE OF CHRONIC TOPHOCEOUS GOUT]. Iryo, 1963, Volume: 17 Topics: Arthritis, Gouty; Aspirin; Diet; Diet Therapy; Gout; Humans; Phenylbutazone; Prednisolone; Sulfinpyr	1963
[PROLONGED USE OF G-28315 IN URIC GOUT]. Hospital (Rio de Janeiro, Brazil), 1963, Volume: 64 Topics: Gout; Humans; Sulfinpyrazone; Uricosuric Agents	1963
[ON GOUT AND A NEW DRUG, ANTURAN]. Orvosi hetilap, 1964, Feb-16, Volume: 105 Topics: Blood Chemical Analysis; Gout; Sulfinpyrazone; Toxicology; Uricosuric Agents	1964
[THE TREATMENT OF CHRONIC INFLAMMATORY RHEUMATISM IN ADULTS]. Marseille medical, 1964, Volume: 101 Topics: Adrenal Cortex Hormones; Antimalarials; Arthritis; Arthritis, Rheumatoid; Aspirin; Colchicine; Colla	1964
THE MODERN MANAGEMENT OF GOUT. Applied therapeutics, 1964, Volume: 6 Topics: Adrenocorticotropic Hormone; Blood; Body Fluids; Colchicine; Diet; Diet Therapy; Disease Management;	1964
[ON THE EFFECT OF ANTURAN AS A TREATMENT OF GOUT]. [Sogo rinsho] Clinic all-round, 1964, Volume: 13 Topics: Biomedical Research; Geriatrics; Gout; Sulfinpyrazone; Toxicology; Uric Acid; Uricosuric Agents	1964
EXHIBIT ON GOUT. Boletin de la Asociacion Medica de Puerto Rico, 1964, Volume: 56 Topics: Colchicine; Exhibitions as Topic; Gout; Humans; Metabolism; Probenecid; Purines; Sulfinpyrazone; Uri	1964
EFFECT OF SULFINPYRAZONE ON TOTAL SERUM CHOLESTEROL IN GOUT: A LONG-TERM STUDY. The American journal of the medical sciences, 1964, Volume: 248 Topics: Biomedical Research; Cholesterol; Drug Therapy; Gout; Lipid Metabolism; Longitudinal Studies; Statis	1964
THE TREATMENT OF GOUT. The New Zealand medical journal, 1964, Volume: 63 Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Colchicine; Diet; Diet Therapy; Dr	1964
GOUT. The Practitioner, 1964, Volume: 193 Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Colchicine; Diagnosis, Differential; Diet; Diet	1964
EFFECT OF SULFINPYRAZONE ON SERUM URIC ACID IN GOUT. A LONG-TERM STUDY. Geriatrics, 1964, Volume: 19 Topics: Adolescent; Aging; Blood; Drug Therapy; Geriatrics; Gout; Longitudinal Studies; Metabolism; Phenylbu	1964
[G 28315 (SULFINPYRAZONE) IN THE TREATMENT OF GOUT]. Hospital (Rio de Janeiro, Brazil), 1964, Volume: 66 Topics: Drug Therapy; Gout; Sulfinpyrazone	1964
[CLINICAL TRIAL OF G 28315 IN GOUTY ARTHROPATHY]. Hospital (Rio de Janeiro, Brazil), 1964, Volume: 66 Topics: Arthritis, Gouty; Drug Therapy; Gout; Humans; Sulfinpyrazone	1964
THE PROGRESSIVE NATURE OF GOUT WITH INADEQUATE THERAPY. Arthritis and rheumatism, 1965, Volume: 8 Topics: Diagnosis; Drug Therapy; Gout; Humans; Pathology; Probenecid; Radiography; Sulfinpyrazone	1965
[GOUT AND ITS TREATMENT WITH ANTURANE]. Wiener klinische Wochenschrift, 1965, Feb-05, Volume: 77 Topics: Arthritis; Arthritis, Rheumatoid; Blood; Diabetes Mellitus; Drug Therapy; Gout; Humans; Obesity; Sul	1965
PATHOGENIC AND THERAPEUTIC CONSIDERATIONS ON CHRONIC GOUT. Archives of interamerican rheumatology : A.I.R, 1964, Volume: 7 Topics: Arthritis, Gouty; Drug Therapy; Gout; Physiology; Sulfinpyrazone; Toxicology; Uric Acid	1964
THE EFFECT OF SULFINPYRAZONE (ANTURAN) ON PLATELET ECONOMY AND BLOOD COAGULATION IN MAN. Canadian Medical Association journal, 1965, Apr-10, Volume: 92 Topics: Arthritis; Arthritis, Rheumatoid; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Drug	1965
THE RENAL EXCRETION OF OXYPURINES. The Journal of clinical investigation, 1965, Volume: 44 Topics: Enzyme Inhibitors; Fluids and Secretions; Gout; Hypoxanthines; Kidney; Pharmacology; Physiology; Pro	1965
[GOUT, DIAGNOSIS AND TREATMENT]. Belgisch tijdschrift voor geneeskunde, 1965, Jan-01, Volume: 21 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Colchicine; Diagnosis; Drug Therapy; Gout; Hum	1965
URATE DIURETIC THERAPY IN CHRONIC GOUT; A COMPARATIVE STUDY OF PROBENECID AND SULFINPYRAZONE. Archives of internal medicine, 1965, Volume: 116 Topics: Arthritis, Gouty; Biomedical Research; Blood; Diuretics; Drug Therapy; Gout; Humans; Kidney Calculi;	1965
ACUTE ANAPHYLACTOID REACTION TO PROBENECID. JAMA, 1965, Aug-30, Volume: 193 Topics: Anaphylaxis; Colchicine; Diagnosis, Differential; Drug Therapy; Gout; Myocardial Infarction; Probene	1965
[Clinical trials with a ne uricosuric agent, G 28,315 or anturan]. Schweizerische medizinische Wochenschrift, 1960, Jul-09, Volume: 90 Topics: Gout; Phenylbutazone; Sulfinpyrazone; Uricosuric Agents	1960
[Experiences with gout, especially with uricosuric therapy using anturan]. Zeitschrift fur Rheumaforschung, 1962, Volume: 21 Topics: Gout; Phenylbutazone; Sulfinpyrazone	1962
Uric acid lowering therapy: prescribing patterns in a large cohort of older adults. Annals of the rheumatic diseases, 2008, Volume: 67, Issue:5 Topics: Age Factors; Aged; Aged, 80 and over; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Black or	2008
[On gout]. Munchener medizinische Wochenschrift (1950), 1966, Jan-14, Volume: 108, Issue:2 Topics: Adult; Ankle Joint; Diet Therapy; Female; Gout; Humans; Male; Middle Aged; Phenylbutazone; Sulfinpyr	1966
Therapy of gout. The Johns Hopkins medical journal, 1967, Volume: 121, Issue:5 Topics: Allopurinol; Colchicine; Gout; Humans; Phenylbutazone; Probenecid; Sulfinpyrazone	1967
Allopurinol in the treatment of gout. The Journal-lancet, 1967, Volume: 87, Issue:10 Topics: Allopurinol; Drug Synergism; Gout; Humans; Sulfinpyrazone	1967
An approach to hyperuricemia and gout. Geriatrics, 1984, Volume: 39, Issue:11 Topics: Allopurinol; Anti-Inflammatory Agents; Colchicine; Female; Gout; Humans; Male; Naproxen; Phenylbutaz	1984
Sulphinpyrazone-induced acute renal failure. British medical journal (Clinical research ed.), 1981, Feb-21, Volume: 282, Issue:6264 Topics: Acute Kidney Injury; Gout; Humans; Kidney; Kidney Tubular Necrosis, Acute; Male; Middle Aged; Sulfin	1981
[Effect of long-term base therapy on the clinical picture of gout]. Terapevticheskii arkhiv, 1981, Volume: 53, Issue:2 Topics: Adult; Allopurinol; Chronic Disease; Drug Evaluation; Drug Therapy, Combination; Female; Gout; Human	1981
Practical therapeutics treatment of gout. East African medical journal, 1981, Volume: 58, Issue:3 Topics: Colchicine; Female; Gout; Humans; Indomethacin; Male; Phenylbutazone; Probenecid; Sulfinpyrazone	1981
[Changes in indications for drugs]. La Revue du praticien, 1980, Feb-01, Volume: 30, Issue:7 Topics: Amantadine; Clofibrate; Colchicine; Drug Therapy; Female; Gout; Humans; Levamisole; Metronidazole; M	1980
Changing trends of mortality in gout. Seminars in arthritis and rheumatism, 1980, Volume: 10, Issue:1 Topics: Aged; Arteriosclerosis; Coronary Disease; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged;	1980
[Physiopathological bases for a rational therapy of gout]. Minerva medica, 1978, Feb-04, Volume: 69, Issue:6 Topics: Allopurinol; Benzofurans; Gout; Humans; Life Style; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric	1978
Management of gout. Annals of internal medicine, 1979, Volume: 90, Issue:5 Topics: Adrenal Cortex Hormones; Allopurinol; Colchicine; Female; Gout; Humans; Indomethacin; Patient Educat	1979
Gout. British medical journal, 1979, Jun-23, Volume: 1, Issue:6179 Topics: Colchicine; Cortisone; Gout; Humans; Male; Probenecid; Sulfinpyrazone	1979
The management of gout. Hospital practice, 1979, Volume: 14, Issue:9 Topics: Allopurinol; Colchicine; Gout; Humans; Indomethacin; Male; Oxyphenbutazone; Phenylbutazone; Probenec	1979
Treatment of gout with alternate-day hypo-uricaemic drugs. Rheumatology and rehabilitation, 1978, Volume: 17, Issue:3 Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Female; Gout; Humans; Male; Middle Aged; Sulfi	1978
Management of gout. American family physician, 1979, Volume: 19, Issue:1 Topics: Allopurinol; Colchicine; Gout; Humans; Phenylbutazone; Probenecid; Sulfinpyrazone	1979
[Drug therapy in uratic arthritis. II. Prevention of new attacks]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1977, May-30, Volume: 97, Issue:15 Topics: Allopurinol; Gout; Humans; Probenecid; Sulfinpyrazone	1977
Drugs for gout. The Medical letter on drugs and therapeutics, 1976, Jun-04, Volume: 18, Issue:12 Topics: Allopurinol; Colchicine; Gout; Humans; Indomethacin; Oxyphenbutazone; Phenylbutazone; Probenecid; Su	1976
Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone. The Journal of rheumatology, 1976, Volume: 3, Issue:3 Topics: Adult; Aged; Arthritis; Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Chronic Disease;	1976
Current therapy of gout and hyperuricemia. Hospital practice, 1976, Volume: 11, Issue:5 Topics: Allopurinol; Colchicine; Drug Interactions; Gout; Humans; Indomethacin; Phenylbutazone; Probenecid;	1976
Acute myelomonocytic leukaemia and multiple myeloma after sulphinpyrazone and colchicine treatment of gout. British medical journal, 1976, Jul-10, Volume: 2, Issue:6027 Topics: Aged; Colchicine; Gout; Humans; Leukemia, Myeloid, Acute; Male; Multiple Myeloma; Sulfinpyrazone	1976
Decreasing prevalence of tophaceous gout. Mayo Clinic proceedings, 1975, Volume: 50, Issue:5 Topics: Colchicine; Gout; Humans; Minnesota; Probenecid; Retrospective Studies; Sulfinpyrazone	1975
The pharmacology of hypouricemic effect of benzbromarone. The Journal of rheumatology, 1975, Volume: 2, Issue:4 Topics: Adult; Aspirin; Benzbromarone; Benzofurans; Blood Proteins; Creatinine; Female; Gout; Humans; Male;	1975
Uricosuric activity of suxibuzone, a new phenylbutazone derivative. Archivos de farmacologia y toxicologia, 1975, Volume: 1, Issue:1 Topics: Adolescent; Adult; Drug Evaluation; Gout; Humans; Phenylbutazone; Sulfinpyrazone; Uric Acid; Uricosu	1975
Hyperuricemia and gout. The Western journal of medicine, 1985, Volume: 142, Issue:1 Topics: Allopurinol; Anti-Inflammatory Agents; Arthritis; Colchicine; Female; Gout; Humans; Indomethacin; Ki	1985
Drugs in the treatment of hyperuricemia. Advances in nephrology from the Necker Hospital, 1974, Volume: 3 Topics: Allopurinol; Gout; Humans; Oxypurinol; Probenecid; Sulfinpyrazone; Uric Acid; Uricosuric Agents	1974
Zyloprim and other drugs in the management of gout. The Medical letter on drugs and therapeutics, 1966, Dec-02, Volume: 8, Issue:24 Topics: Adrenocorticotropic Hormone; Colchicine; Enzyme Therapy; Enzymes; Gout; Humans; Indomethacin; Proben	1966
[The treatment of gout and the internal medical treatment of uric acid nephrolithiasis]. Deutsche medizinische Wochenschrift (1946), 1968, Feb-16, Volume: 93, Issue:7 Topics: Adrenocorticotropic Hormone; Allopurinol; Colchicine; Gout; Humans; Indomethacin; Kidney Calculi; Pr	1968
Recent developments in the therapy of gout. Journal of the American Geriatrics Society, 1968, Volume: 16, Issue:5 Topics: Acute Disease; Adrenocorticotropic Hormone; Allopurinol; Analgesics; Colchicine; Gout; Humans; Oxyph	1968
[How to treat gout]. Revista espanola de reumatismo y enfermedades osteoarticulares, 1966, Volume: 11, Issue:7 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticoagulants; Benzofurans; Colchicine; Gout;	1966
Pharmacologic effects of nicotinic acid on human purine metabolism. The Journal of laboratory and clinical medicine, 1974, Volume: 84, Issue:2 Topics: Adult; Aspirin; Creatinine; Erythrocytes; Female; Gout; Humans; Iopanoic Acid; Kidney Tubules; Male;	1974
The treatment of gout. Scottish medical journal, 1973, Volume: 18 Topics: Acute Disease; Allopurinol; Aspirin; Colchicine; Drug Therapy, Combination; Gout; Indomethacin; Phen	1973
The binding of urate to plasma proteins. Advances in experimental medicine and biology, 1974, Volume: 41 Topics: Allopurinol; Aspirin; Binding Sites; Blood Proteins; Colchicine; Dialysis; Evaluation Studies as Top	1974
Medical management of gout. Postgraduate medicine, 1972, Volume: 51, Issue:6 Topics: Adult; Allopurinol; Colchicine; Diet Therapy; Female; Gout; Humans; Kidney Diseases; Male; Middle Ag	1972
[Gout]. Naika. Internal medicine, 1971, Volume: 27, Issue:6 Topics: Adult; Allopurinol; Benzofurans; Colchicine; Gout; Humans; Ketones; Male; Middle Aged; Sulfinpyrazon	1971
[Gout]. Nihon Seikeigeka Gakkai zasshi, 1971, Volume: 45, Issue:8 Topics: Adolescent; Adult; Aged; Arthritis; Colchicine; Diet Therapy; Female; Gout; Griseofulvin; Humans; Ja	1971
Allopurinol in the treatment of gout. The Nova Scotia medical bulletin, 1969, Volume: 48, Issue:4 Topics: Adult; Aged; Allopurinol; Female; Gout; Humans; Male; Sulfinpyrazone; Uric Acid	1969
[Our experience with G 28315 in gouty arthropathy]. Hospital (Rio de Janeiro, Brazil), 1965, Volume: 68, Issue:6 Topics: Adult; Aged; Female; Gout; Humans; Male; Middle Aged; Sulfinpyrazone	1965
[Treatment of gout and of certain rheumatisms with hyperuricemia caused by benziodarone]. Revue du rhumatisme et des maladies osteo-articulaires, 1968, Volume: 35, Issue:3 Topics: Adult; Arthritis, Rheumatoid; Benzofurans; Female; Gout; Humans; Male; Rheumatic Diseases; Sulfinpyr	1968
[Gout from the view of a special hospital for rheumatic patients]. Wiener klinische Wochenschrift, 1971, Mar-19, Volume: 83, Issue:11 Topics: Acute Disease; Adolescent; Adult; Aged; Austria; Child; Cholesterol; Colchicine; Colic; Diabetes Com	1971
[Clinical findings and therapy of gout with special reference to the metabolic effects of sulfinpyrazone (Anturan) and allopurinol (Zyloric)]. Wiener klinische Wochenschrift, 1969, Nov-07, Volume: 81, Issue:45 Topics: Allopurinol; Diabetes Mellitus; Gout; Humans; Hypertension; Kidney Diseases; Male; Sulfinpyrazone; U	1969
[Gout in dermatology]. Zeitschrift fur Haut- und Geschlechtskrankheiten, 1969, Oct-15, Volume: 44, Issue:20 Topics: Adolescent; Aged; Colchicine; Diagnosis, Differential; Gout; Humans; Indomethacin; Joint Diseases; M	1969
Long-term use of allopurinol in the treatment of gout. Annals of the rheumatic diseases, 1970, Volume: 29, Issue:1 Topics: Adolescent; Aged; Allopurinol; Colic; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged; Sulf	1970
Pathogenesis and medical management of chronic gouty arthritis. Clinical orthopaedics and related research, 1970, Volume: 71 Topics: Allopurinol; Chronic Disease; Colchicine; Gout; Humans; Joints; Kidney; Probenecid; Sulfinpyrazone;	1970
[Treatment of the gouty diathesis with a xanthine oxidase inhibitor. A clinical trial of allopurinol]. Ugeskrift for laeger, 1967, Feb-23, Volume: 129, Issue:8 Topics: Aged; Allopurinol; Drug Synergism; Gout; Humans; Male; Middle Aged; Phenylbutazone; Sulfinpyrazone;	1967
Long-term treatment of gout with "allopurinol". Acta rheumatologica Scandinavica, 1968, Volume: 14, Issue:1 Topics: Allopurinol; Chronic Disease; Colchicine; Colorimetry; Female; Gout; Humans; Male; Purines; Sulfinpy	1968
[Therapy of arthritis urica]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1968, Apr-01, Volume: 88, Issue:7 Topics: Analgesics; Diet Therapy; Gout; Humans; Probenecid; Sulfinpyrazone	1968
Etiology and treatment of gout--modern concepts. Journal of the American Geriatrics Society, 1968, Volume: 16, Issue:6 Topics: Allopurinol; Colchicine; Crystallization; Diagnosis, Differential; Diet Therapy; Gout; Humans; Indom	1968
A short trial assessment of uricosuric therapy in gout. Australasian annals of medicine, 1968, Volume: 17, Issue:3 Topics: Adult; Aged; Allopurinol; Female; Glomerular Filtration Rate; Gout; Humans; Male; Middle Aged; Probe	1968
Estimation of uricosuric activity of sulfinpyrazone in healthy adults. Zeitschrift fur Rheumaforschung, 1968, Volume: 27, Issue:3 Topics: Adult; Creatinine; Gout; Humans; Sulfinpyrazone; Uric Acid	1968
[On the influence of Anturan on ric acid and plasma lipids in patients with gout]. Wiener klinische Wochenschrift, 1968, Jun-14, Volume: 80, Issue:24 Topics: Adult; Age Factors; Aged; Animals; Body Weight; Cholesterol; Diet Therapy; Fatty Acids, Nonesterifie	1968
Pyrazolidines in the treatment of gout. Canadian Medical Association journal, 1968, Nov-30, Volume: 99, Issue:21 Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents; Chronic Disease; Gout; Humans; Oxyphenbutazone	1968
[Results of long-term treatment of gout using Anturane]. Revista espanola de reumatismo y enfermedades osteoarticulares, 1968, Volume: 12, Issue:5 Topics: Adult; Female; Gout; Humans; Male; Middle Aged; Sulfinpyrazone; Time Factors	1968
[Gout in advanced age]. Munchener medizinische Wochenschrift (1950), 1968, Mar-15, Volume: 110, Issue:11 Topics: Age Factors; Aged; Allopurinol; Bone and Bones; Cardiovascular Diseases; Colchicine; Female; Gout; H	1968
Goals in gout. Postgraduate medicine, 1969, Volume: 45, Issue:1 Topics: Allopurinol; Colchicine; Gout; Humans; Probenecid; Sulfinpyrazone	1969
[Gout, diuretic treatment and combined drug therapy during the cure]. La Presse thermale et climatique, 1965, Volume: 102, Issue:4 Topics: Gout; Humans; Mineral Waters; Sulfinpyrazone	1965
The treatment of gout and disorders of uric acid metabolism with allopurinol. Canadian Medical Association journal, 1966, Nov-26, Volume: 95, Issue:22 Topics: Aged; Colchicine; Diet; Enzyme Therapy; Female; Gout; Humans; Male; Middle Aged; Sulfinpyrazone; Uri	1966
The pharmaceutical treatment of gout. Annals of physical medicine, 1966, Volume: 8, Issue:6 Topics: Enzyme Therapy; Gout; Humans; Indomethacin; Phenylbutazone; Sulfinpyrazone; Uric Acid; Xanthine Oxid	1966
Effects of allopurinol, a xanthine oxidase inhibitor, and sulfinpyrazone upon the urinary and serum urate concentrations in eight patients with tophaceous gout. Arthritis and rheumatism, 1966, Volume: 9, Issue:3 Topics: Aged; Blood; Drug Synergism; Enzyme Therapy; Gout; Humans; Middle Aged; Pyrimidines; Sulfinpyrazone;	1966
Treatment of gout by reduction of uric acid production. Annals of the rheumatic diseases, 1966, Volume: 25, Issue:4 Topics: Catalase; Drug Synergism; Enzyme Therapy; Gout; Humans; Kidney Calculi; Sulfinpyrazone; Uracil; Uric	1966
Allopurinol (xanthine oxidase inhibitor) in the treatment of resistant gout. JAMA, 1966, Nov-14, Volume: 198, Issue:7 Topics: Adult; Aged; Colchicine; Enzyme Therapy; Enzymes; Female; Gout; Humans; Male; Middle Aged; Probeneci	1966
Allopurinol in primary gout with and after the administration of uricosuric agents. Annals of the rheumatic diseases, 1966, Volume: 25, Issue:6 Suppl Topics: Allopurinol; Drug Synergism; Enzyme Therapy; Female; Gout; Humans; Male; Sulfinpyrazone; Uric Acid;	1966
Effects of allopurinol on gouty and non-gouty uric acid nephropathy. Annals of the rheumatic diseases, 1966, Volume: 25, Issue:6 Suppl Topics: Allopurinol; Blood Urea Nitrogen; Enzyme Therapy; Female; Gout; Humans; Kidney Calculi; Kidney Disea	1966

sulfinpyrazone and Gout

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