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sulfinpyrazone and Cardiovascular Diseases

sulfinpyrazone has been researched along with Cardiovascular Diseases in 15 studies

Sulfinpyrazone: A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
"Aspirin has been convincingly shown to reduce stroke and death in men with transient ischemic attacks (it may possibly be beneficial to women also), myocardial infarction and death in patients with unstable angina, thromboembolic complications associated with artificial heart valves in patients receiving oral anticoagulants (although gastrointestinal bleeding is prohibitive with this combination), and thrombotic occlusion of silicone rubber arteriovenous cannulae in uremic patients undergoing hemodialysis."6.15Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis. ( Harker, LA, 1986)
"Sulfinpyrazone1 has long been recognised as a potent uricosuric agent, but has more recently been studied extensively as a platelet inhibitor and antithrombotic agent."3.75Sulfinpyrazone: a review of its pharmacological properties and therapeutic use. ( Margulies, EH; Sherry, S; White, AM, 1980)
"Aspirin has been shown to reduce the number of transient ischemic attacks (TIA), stroke and death in patients with multiple TIA."3.75Antithrombotic effects of drugs which suppress platelet function: their potential in prevention growth of tumour cells. ( Turpie, AG, 1982)
"Results of recent clinical trials on secondary prevention of ischemic heart disease indicate that judicious, long-term administration of adrenergic beta blockers and platelet-active drugs such as aspirin and Persantine (dipyridamole) would seem to yield protection against mortality associated with acute myocardial infarction, including sudden death."3.67Clinical trials on the efficacy of pharmacologic intervention reducing mortality from cardiovascular diseases. ( Borhani, NO, 1985)
" Seven recently completed clinical trials, the Coronary Drug Project, the Aspirin Myocardial Infarction Study, the Anturane Reinfarction Trial, the Hypertension Detection and Follow-Up Program and three drug trials of betablockers, are reviewed from the perspective of both their clinical and methodological significance."3.66Overview of recent clinical and methodological advances from clinical trials of cardiovascular disease. ( Friedewald, WT; Schoenberger, JA, 1982)
" Starting dosage was 200 mg per day; daily dosage was then increased, every 4 days, by 200 mg or kept constant for another 4 days, according to each patient's basal renal function, up to the maintenance dose: 800 mg/day."1.27Sulphinpyrazone in cardiovascular elderly azotemic patients: a proposal of a 'guided' incremental dose schedule. ( Borghi, C; Dacco', L; Di Ruvo, R; Palummeri, E; Passeri, M, 1984)
" Each patient was allocated, according to his/her baseline values of serum uric acid or serum creatinine to four different sulphinpyrazone incremental dosage schedules."1.27Sulphinpyrazone dose schedule in hyperuricemic patients with cardiovascular diseases: tolerability assessment. ( Bertoli, L; Borghi, C; Busnardo, I; Zagnoni, P, 1985)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199015 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Friedewald, WT1
Schoenberger, JA1
Palummeri, E1
Borghi, C2
Di Ruvo, R1
Dacco', L1
Passeri, M1
Giannini, SD1
Sanchis, FS1
Guerra, JL1
Merusse, JL1
Birgens, HS1
Hansen, MS1
Margulies, EH1
White, AM1
Sherry, S1
Weiss, HJ1
Turpie, AG1
Boeynaems, JM1
Jobin, F1
Rubegni, M1
Provvedi, D1
Bellini, PG1
Bandinelli, C1
De Mauro, G1
Gantmacher, ML1
Borhani, NO1
Harker, LA1
Bertoli, L1
Busnardo, I1
Zagnoni, P1
Holländer, E1
Schwarczmann, P1

Reviews

7 reviews available for sulfinpyrazone and Cardiovascular Diseases

ArticleYear
[Prevention of thrombosis by thrombocyte inhibition. 2. Clinical results].
    Ugeskrift for laeger, 1980, Jan-28, Volume: 142, Issue:5

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Cerebrovascular Disorders; Clofibrate; Dextrans;

1980
Sulfinpyrazone: a review of its pharmacological properties and therapeutic use.
    Drugs, 1980, Volume: 20, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Antibody Formation; Aspirin; Blood Platelets; Cardiovascular Diseas

1980
Platelet-active drugs in the secondary prevention of cardiovascular events: an overview.
    Circulation, 1980, Volume: 62, Issue:6 Pt 2

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Coronary Disease; Dipyridamole; Sulfinpyrazone; T

1980
Antithrombotic effects of drugs which suppress platelet function: their potential in prevention growth of tumour cells.
    Progress in clinical and biological research, 1982, Volume: 89

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Cell Division; Clinical Trials as Topic; Coronary

1982
[Blood platelets and cardiovascular diseases. IV. Platelet-inhibiting drugs and antithrombotic agents].
    L'union medicale du Canada, 1976, Volume: 105, Issue:8

    Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Analgesics; Anti-Inflammatory Agents; Arterioscl

1976
Antiplatelet agents: a review.
    Journal of the Royal Society of Medicine, 1979, Volume: 72, Issue:7

    Topics: Angina Pectoris; Aspirin; Blood Platelets; Cardiovascular Diseases; Cerebrovascular Disorders; Clofi

1979
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
    Circulation, 1986, Volume: 73, Issue:2

    Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical

1986

Trials

3 trials available for sulfinpyrazone and Cardiovascular Diseases

ArticleYear
Sulfinpyrazone: a review of its pharmacological properties and therapeutic use.
    Drugs, 1980, Volume: 20, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Antibody Formation; Aspirin; Blood Platelets; Cardiovascular Diseas

1980
Antithrombotic effects of drugs which suppress platelet function: their potential in prevention growth of tumour cells.
    Progress in clinical and biological research, 1982, Volume: 89

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Cell Division; Clinical Trials as Topic; Coronary

1982
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
    Circulation, 1986, Volume: 73, Issue:2

    Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical

1986

Other Studies

8 other studies available for sulfinpyrazone and Cardiovascular Diseases

ArticleYear
Overview of recent clinical and methodological advances from clinical trials of cardiovascular disease.
    Controlled clinical trials, 1982, Volume: 3, Issue:3

    Topics: Adrenergic beta-Antagonists; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Di

1982
Sulphinpyrazone in cardiovascular elderly azotemic patients: a proposal of a 'guided' incremental dose schedule.
    The Journal of international medical research, 1984, Volume: 12, Issue:5

    Topics: Aged; Cardiovascular Diseases; Drug Administration Schedule; Drug Tolerance; Female; Humans; Kidney

1984
[Cardiovascular lesions induced in rats by vitamin D. Possible protective effect of sulfinpyrazone].
    Arquivos brasileiros de cardiologia, 1983, Volume: 41, Issue:3

    Topics: Animals; Arteries; Cardiovascular Diseases; Dipyridamole; Male; Myocardium; Necrosis; Oxyphenbutazon

1983
[Prevention of cardiovascular diseases by inhibitors of platelet aggregation (author's transl)].
    Revue medicale de Bruxelles, 1982, Volume: 3, Issue:6

    Topics: Anti-Inflammatory Agents; Aspirin; Cardiovascular Diseases; Dipyridamole; Humans; Platelet Aggregati

1982
[Anti-platelet aggregating drugs in the prevention of thromboembolic diseases].
    Minerva medica, 1975, May-12, Volume: 66, Issue:36

    Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents; Cardiovascular Diseases; Cerebrovascular Diso

1975
Clinical trials on the efficacy of pharmacologic intervention reducing mortality from cardiovascular diseases.
    Cardiology, 1985, Volume: 72, Issue:5-6

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Clofibrate;

1985
Sulphinpyrazone dose schedule in hyperuricemic patients with cardiovascular diseases: tolerability assessment.
    Pharmacological research communications, 1985, Volume: 17, Issue:3

    Topics: Allopurinol; Cardiovascular Diseases; Creatinine; Drug Tolerance; Female; Humans; Kidney Function Te

1985
[Gout in advanced age].
    Munchener medizinische Wochenschrift (1950), 1968, Mar-15, Volume: 110, Issue:11

    Topics: Age Factors; Aged; Allopurinol; Bone and Bones; Cardiovascular Diseases; Colchicine; Female; Gout; H

1968