sulfasalazine has been researched along with Thrombopenia in 13 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 56 year old woman with rheumatoid arthritis developed relapsing thrombocytopenia during successive treatments with aurothioglucose, sulphasalazine, and hydroxychloroquine." | 7.68 | Thrombocytopenia due to aurothioglucose, sulphasalazine, and hydroxychloroquine. ( Allebes, WA; Boerbooms, AM; van de Putte, LB; van Riel, PL; Wijnands, MJ, 1990) |
| "The long term efficacy and tolerability of sulphasalazine (SASP) in the treatment of 21 patients with active classical or definite rheumatoid arthritis (RA) were examined and compared with the effects of penicillamine in a similarly active group of RA patients." | 7.67 | The long term effects of sulphasalazine in the treatment of rheumatoid arthritis and a comparative study with penicillamine. ( Bacon, PA; Crockson, AP; Farr, M; Tunn, E, 1984) |
| "A 56 year old woman with rheumatoid arthritis developed relapsing thrombocytopenia during successive treatments with aurothioglucose, sulphasalazine, and hydroxychloroquine." | 3.68 | Thrombocytopenia due to aurothioglucose, sulphasalazine, and hydroxychloroquine. ( Allebes, WA; Boerbooms, AM; van de Putte, LB; van Riel, PL; Wijnands, MJ, 1990) |
| "The long term efficacy and tolerability of sulphasalazine (SASP) in the treatment of 21 patients with active classical or definite rheumatoid arthritis (RA) were examined and compared with the effects of penicillamine in a similarly active group of RA patients." | 3.67 | The long term effects of sulphasalazine in the treatment of rheumatoid arthritis and a comparative study with penicillamine. ( Bacon, PA; Crockson, AP; Farr, M; Tunn, E, 1984) |
| "A 12-year-old girl with juvenile rheumatoid arthritis developed fulminant hepatic failure, thrombocytopenia and erythroid hypoplasia, which was confirmed by liver histology and bone marrow examination, 2 weeks after initiation of sulphasalazine therapy." | 1.30 | Successfully treated sulphasalazine-induced fulminant hepatic failure, thrombocytopenia and erythroid hypoplasia with intravenous immunoglobulin. ( Chen, LC; Hsieh, KH; Hsueh, C; Huang, JL; Hung, IJ; Lee, WY, 1998) |
| " In this study we determined the activity and toxicity of melphalan in combination with another GST-activity inhibitor, sulfasalazine, an agent used to treat ulcerative colitis." | 1.29 | Activity of melphalan in combination with the glutathione transferase inhibitor sulfasalazine. ( Awasthi, S; Awasthi, YC; Fields, L; Gupta, V; Jacobs, S; Jani, JP; Levitt, M; Singh, SV; Sreevardhan, M; Xu, BH, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Masuda, H | 1 |
| Takahashi, Y | 1 |
| Nishida, Y | 1 |
| Asai, S | 1 |
| Danielson, DA | 1 |
| Douglas, SW | 1 |
| Herzog, P | 1 |
| Jick, H | 1 |
| Porter, JB | 1 |
| Farr, M | 2 |
| Tunn, E | 2 |
| Crockson, AP | 1 |
| Bacon, PA | 2 |
| Gupta, V | 1 |
| Jani, JP | 1 |
| Jacobs, S | 1 |
| Levitt, M | 1 |
| Fields, L | 1 |
| Awasthi, S | 1 |
| Xu, BH | 1 |
| Sreevardhan, M | 1 |
| Awasthi, YC | 1 |
| Singh, SV | 1 |
| McKenna, KE | 1 |
| Burrows, D | 1 |
| Huang, JL | 1 |
| Hung, IJ | 1 |
| Chen, LC | 1 |
| Lee, WY | 1 |
| Hsueh, C | 1 |
| Hsieh, KH | 1 |
| Keso, L | 1 |
| Kaarela, K | 1 |
| Oksanen, K | 1 |
| Ahonen, M | 1 |
| Eisenlohr, H | 1 |
| Trenkwalder, P | 1 |
| Lydtin, H | 1 |
| Wijnands, MJ | 1 |
| Allebes, WA | 1 |
| Boerbooms, AM | 1 |
| van de Putte, LB | 1 |
| van Riel, PL | 1 |
| Gremse, DA | 1 |
| Bancroft, J | 1 |
| Moyer, MS | 1 |
| Peña, JM | 1 |
| Gonzalez-Garcia, JJ | 1 |
| Garcia-Alegria, J | 1 |
| Barbado, FJ | 1 |
| Vazquez, JJ | 1 |
| Smith, DH | 1 |
| Muirden, KD | 1 |
1 review available for sulfasalazine and Thrombopenia
| Article | Year |
|---|---|
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T | 1986 |
1 trial available for sulfasalazine and Thrombopenia
| Article | Year |
|---|---|
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T | 1986 |
12 other studies available for sulfasalazine and Thrombopenia
| Article | Year |
|---|---|
Comparison of the effect of mesalazine and sulfasalazine on laboratory parameters: a retrospective observational study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Cohort Studi | 2012 |
Drug-induced blood disorders.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Anemia, Hemolytic; Child; Female; Hematologic Diseases; Hu | 1984 |
The long term effects of sulphasalazine in the treatment of rheumatoid arthritis and a comparative study with penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Eruptions; Drug Tolerance; Dyspepsia; Female; Humans; Male; | 1984 |
Activity of melphalan in combination with the glutathione transferase inhibitor sulfasalazine.
Topics: Drug Administration Schedule; Drug Therapy, Combination; Female; Glutathione Transferase; Humans; Ma | 1995 |
Leucopenia, thrombocytopenia and lymphadenopathy associated with sulphasalazine.
Topics: Adult; Female; Humans; Leukopenia; Lymphatic Diseases; Psoriasis; Sulfasalazine; Thrombocytopenia | 1994 |
Successfully treated sulphasalazine-induced fulminant hepatic failure, thrombocytopenia and erythroid hypoplasia with intravenous immunoglobulin.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Follow-Up Studies; Hepatic Encephalopathy; | 1998 |
[Thrombocytopenia in a patient with rheumatoid arthritis during sulphasalazine therapy].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Blood Platelets; Diagnosis, Differential; Humans; Male; | 1998 |
[Heparin-induced thrombosis-thrombocytopenia syndrome in Crohn disease. Further thromboses with oral anticoagulation after discontinuation of heparin].
Topics: Administration, Oral; Blood Coagulation Tests; Crohn Disease; Drug Therapy, Combination; Female; Hep | 1992 |
Thrombocytopenia due to aurothioglucose, sulphasalazine, and hydroxychloroquine.
Topics: Arthritis, Rheumatoid; Aurothioglucose; Female; HLA-B8 Antigen; HLA-DR3 Antigen; Humans; Hydroxychlo | 1990 |
Sulfasalazine hypersensitivity with hepatotoxicity, thrombocytopenia, and erythroid hypoplasia.
Topics: Anemia; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Child; Drug Hypersensitivity; | 1989 |
Thrombocytopenia and sulfasalazine.
Topics: Adolescent; Colitis, Ulcerative; Humans; Male; Sulfasalazine; Thrombocytopenia | 1985 |
Hypogammaglobulinaemia and thrombocytopenia associated with sulphasalazine therapy in rheumatoid arthritis.
Topics: Agammaglobulinemia; Arthritis, Rheumatoid; Female; Humans; Middle Aged; Sulfasalazine; Thrombocytope | 1985 |