sulfasalazine has been researched along with Syndrome in 37 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 24-year-old female developed DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) as a result of sulfasalazine use." | 7.76 | [DRESS syndrome as a result of sulfasalazine use]. ( Bakker, RC; Segers, D; van der Mark, SC; van Wijngaarden, P, 2010) |
| " We describe a 60-year-old man with polyarthritis treated with sulfasalazine who developed DRESS and fulminant liver failure after additional vancomycin treatment." | 7.75 | Fulminant liver failure after vancomycin in a sulfasalazine-induced DRESS syndrome: fatal recurrence after liver transplantation. ( Candinas, D; Inderbitzin, D; Keller, M; Keogh, A; Mennicke, M; Pichler, WJ; Stickel, F; Wilkens, L; Yawalkar, N; Zawodniak, A, 2009) |
| "The case of a 47-year-old white Brazilian woman who developed DRESS syndrome eight weeks after starting a course of sulfasalazine for treatment of seronegative arthritis is reported." | 7.74 | Sulfasalazine-induced DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms). ( Aquino, RT; de Freitas, TH; Magliari, ME; Vergueiro, CS, 2008) |
| " Two patients presented severe febrile skin eruption following drug intake (carbamazepine or sulfazalazine), with hypereosinophilia and hepatitis." | 7.71 | [DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome after sulfasalazine and carmazepine: report of two cases]. ( Catteau, B; Delcey, V; Devulder, B; Fauchais, AL; Hachulla, E; Hatron, PY; Launay, D; Legout, L; Michon-Pasturel, U; Queyrel, V, 2001) |
| "A severe adverse reaction to sulfasalazine therapy has been associated with hypersensitivity syndrome, the clinical features of which are similar to infectious mononucleosis." | 7.70 | Severe hypersensitivity syndrome due to sulfasalazine associated with reactivation of human herpesvirus 6. ( Hashimoto, K; Inagi, R; Tohyama, M; Urano, Y; Yahata, Y; Yamanishi, K; Yasukawa, M, 1998) |
| "We describe 2 cases of a lupus syndrome induced by sulfasalazine in rheumatoid arthritis." | 7.69 | Sulfasalazine induced lupus in rheumatoid arthritis. ( Andrieu, V; Caulier, M; Dromer, C; Fournie, B; Le Guennec, P, 1994) |
| "We report a 52-yr-old man with ulcerative colitis who developed sulfasalazine-induced pulmonary infiltration with eosinophilia (PIE syndrome), which resolved completely after withdrawal of this drug." | 4.78 | Pulmonary infiltration and eosinophilia associated with sulfasalazine therapy for ulcerative colitis: a case report and review of literature. ( Kishida, T; Kobayashi, M; Nomura, T; Yamada, T; Yamakado, S; Yoshida, Y, 1992) |
| "A 24-year-old female developed DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) as a result of sulfasalazine use." | 3.76 | [DRESS syndrome as a result of sulfasalazine use]. ( Bakker, RC; Segers, D; van der Mark, SC; van Wijngaarden, P, 2010) |
| " We describe a 60-year-old man with polyarthritis treated with sulfasalazine who developed DRESS and fulminant liver failure after additional vancomycin treatment." | 3.75 | Fulminant liver failure after vancomycin in a sulfasalazine-induced DRESS syndrome: fatal recurrence after liver transplantation. ( Candinas, D; Inderbitzin, D; Keller, M; Keogh, A; Mennicke, M; Pichler, WJ; Stickel, F; Wilkens, L; Yawalkar, N; Zawodniak, A, 2009) |
| "The case of a 47-year-old white Brazilian woman who developed DRESS syndrome eight weeks after starting a course of sulfasalazine for treatment of seronegative arthritis is reported." | 3.74 | Sulfasalazine-induced DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms). ( Aquino, RT; de Freitas, TH; Magliari, ME; Vergueiro, CS, 2008) |
| "We describe a patient with drug-induced hypersensitivity syndrome (DIHS) associated with human herpesvirus 6 (HHV-6) and cytomegalovirus (CMV) infection induced by sulfasalazine." | 3.73 | Drug-induced hypersensitivity syndrome associated with human herpesvirus 6 and cytomegalovirus reactivation. ( Hamaguchi, Y; Hasegawa, M; Komura, K; Nagai, M; Sato, S; Takehara, K; Yachie, A; Yukami, T, 2005) |
| "We report a case of drug hypersensibility syndrome (DRESS syndrome) developed one month after initiation of a treatment by sulfasalazine." | 3.73 | [DRESS syndrome to sulfasalzine]. ( Bourguignon, R; Paquet, P; Piérard, GE; Piérrard-Franchimont, C, 2006) |
| " Two patients presented severe febrile skin eruption following drug intake (carbamazepine or sulfazalazine), with hypereosinophilia and hepatitis." | 3.71 | [DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome after sulfasalazine and carmazepine: report of two cases]. ( Catteau, B; Delcey, V; Devulder, B; Fauchais, AL; Hachulla, E; Hatron, PY; Launay, D; Legout, L; Michon-Pasturel, U; Queyrel, V, 2001) |
| "A severe adverse reaction to sulfasalazine therapy has been associated with hypersensitivity syndrome, the clinical features of which are similar to infectious mononucleosis." | 3.70 | Severe hypersensitivity syndrome due to sulfasalazine associated with reactivation of human herpesvirus 6. ( Hashimoto, K; Inagi, R; Tohyama, M; Urano, Y; Yahata, Y; Yamanishi, K; Yasukawa, M, 1998) |
| "We describe 2 cases of a lupus syndrome induced by sulfasalazine in rheumatoid arthritis." | 3.69 | Sulfasalazine induced lupus in rheumatoid arthritis. ( Andrieu, V; Caulier, M; Dromer, C; Fournie, B; Le Guennec, P, 1994) |
| "A case of hemophagocytic syndrome associated with ulcerative colitis is very rare." | 1.36 | [A case of hemophagocytic syndrome in an ulcerative colitis patient]. ( Cheung, DY; Hong, SI; Kim, GM; Kim, JI; Kim, JK; Kim, YC; Lee, HS; Park, SH, 2010) |
| "A kidney biopsy showed acute tubulointerstitial nephritis with an intense lymphocytic infiltrate and tubular necrosis." | 1.35 | A case of sulphasalazine-induced DRESS syndrome with delayed acute interstitial nephritis. ( Augusto, JF; Chennebault, JM; Cousin, M; Croue, A; Sayegh, J; Simon, A; Subra, JF, 2009) |
| "The clinical pattern was similar to infectious mononucleosis including pharyngitis and lymphadenopathy but infection by Epstein Barr virus or cytomegalovirus has been ruled out by serological tests." | 1.27 | [Hepatitis and mononucleosis syndrome related to the ingestion of salazosulfapyridine]. ( Beaugrand, M; Ferrier, JP; Labadie, H, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (8.11) | 18.7374 |
| 1990's | 7 (18.92) | 18.2507 |
| 2000's | 17 (45.95) | 29.6817 |
| 2010's | 10 (27.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, S | 1 |
| Ye, G | 1 |
| Zhang, Y | 1 |
| Guan, S | 1 |
| Liu, X | 1 |
| Ren, W | 1 |
| Tsutsumi, R | 1 |
| Adachi, K | 1 |
| Yoshida, Y | 2 |
| Yamamoto, O | 1 |
| Shenoy, P | 1 |
| Misra, R | 1 |
| Jain, M | 1 |
| Agarwal, V | 1 |
| Aquino, RT | 1 |
| Vergueiro, CS | 1 |
| Magliari, ME | 1 |
| de Freitas, TH | 1 |
| Augusto, JF | 1 |
| Sayegh, J | 1 |
| Simon, A | 1 |
| Croue, A | 1 |
| Chennebault, JM | 1 |
| Cousin, M | 1 |
| Subra, JF | 1 |
| Mennicke, M | 1 |
| Zawodniak, A | 1 |
| Keller, M | 1 |
| Wilkens, L | 1 |
| Yawalkar, N | 1 |
| Stickel, F | 1 |
| Keogh, A | 1 |
| Inderbitzin, D | 1 |
| Candinas, D | 1 |
| Pichler, WJ | 1 |
| Suresh, R | 1 |
| Gupta, S | 1 |
| Sathananthan, R | 1 |
| Bahat, G | 1 |
| Celik, HG | 1 |
| Tufan, F | 1 |
| Saka, B | 1 |
| Santiago, F | 1 |
| Gonçalo, M | 1 |
| Vieira, R | 1 |
| Coelho, S | 1 |
| Figueiredo, A | 1 |
| Kim, YC | 1 |
| Kim, GM | 1 |
| Lee, HS | 1 |
| Hong, SI | 1 |
| Cheung, DY | 1 |
| Kim, JI | 1 |
| Park, SH | 1 |
| Kim, JK | 1 |
| Piñana, E | 1 |
| Lei, SH | 1 |
| Merino, R | 1 |
| Melgosa, M | 1 |
| De La Vega, R | 1 |
| Gonzales-Obeso, E | 1 |
| Ramírez, E | 1 |
| Borobia, A | 1 |
| Carcas, A | 1 |
| Khaled, A | 1 |
| Souissi, A | 1 |
| Zeglaoui, F | 1 |
| El Fekih, N | 1 |
| Daghfous, R | 1 |
| Fazaa, B | 1 |
| van der Mark, SC | 1 |
| Segers, D | 1 |
| Bakker, RC | 1 |
| van Wijngaarden, P | 1 |
| Hewitt, N | 1 |
| Levinson, M | 1 |
| Stephenson, G | 1 |
| Haroon, M | 1 |
| Harney, S | 1 |
| Orita, M | 1 |
| Katakura, Y | 1 |
| Kobayashi, M | 2 |
| Ishii, T | 1 |
| Watanabe, Y | 1 |
| Yotsuyanagi, H | 1 |
| Suzuki, M | 1 |
| Itoh, F | 1 |
| Komura, K | 1 |
| Hasegawa, M | 1 |
| Hamaguchi, Y | 1 |
| Yukami, T | 1 |
| Nagai, M | 1 |
| Yachie, A | 1 |
| Sato, S | 1 |
| Takehara, K | 1 |
| Debarbieux, S | 1 |
| Deroo-Berger, MC | 1 |
| Grande, S | 1 |
| Najioullah, F | 1 |
| Kanitakis, J | 1 |
| Faure, M | 1 |
| Claudy, A | 1 |
| Teo, L | 1 |
| Tan, E | 1 |
| Bejia, I | 1 |
| Ben Hammouda, S | 1 |
| Riahi, K | 1 |
| Zinelabidine, F | 1 |
| Mediouni, B | 1 |
| Touzi, M | 1 |
| Bergaoui, N | 1 |
| Kampmann, P | 1 |
| Højlyng, N | 1 |
| Pedersen, M | 1 |
| Bourguignon, R | 1 |
| Piérrard-Franchimont, C | 1 |
| Paquet, P | 1 |
| Piérard, GE | 1 |
| Nishimura, T | 1 |
| Obata, H | 1 |
| Fujino, H | 1 |
| Sonoda, A | 1 |
| Sakamoto, K | 1 |
| Mizuno, C | 1 |
| Mizuno, M | 1 |
| Shima, T | 1 |
| Nakajyo, S | 1 |
| Fujiyama, Y | 1 |
| Tohyama, M | 2 |
| Hashimoto, K | 2 |
| Caulier, M | 1 |
| Dromer, C | 1 |
| Andrieu, V | 1 |
| Le Guennec, P | 1 |
| Fournie, B | 1 |
| Collange, C | 1 |
| Brantus, JF | 1 |
| Sidot, C | 1 |
| Meunier, PJ | 1 |
| Yahata, Y | 1 |
| Yasukawa, M | 1 |
| Inagi, R | 1 |
| Urano, Y | 1 |
| Yamanishi, K | 1 |
| Sáez, J | 1 |
| Gómez, A | 1 |
| Santos, G | 1 |
| García, C | 1 |
| Griño, P | 1 |
| Quílez, C | 1 |
| Bouyssou-Gauthier, ML | 1 |
| Bédane, C | 1 |
| Boulinguez, S | 1 |
| Bonnetblanc, JM | 1 |
| Descamps, V | 1 |
| Valance, A | 1 |
| Edlinger, C | 1 |
| Fillet, AM | 1 |
| Grossin, M | 1 |
| Lebrun-Vignes, B | 1 |
| Belaich, S | 1 |
| Crickx, B | 1 |
| Queyrel, V | 1 |
| Catteau, B | 1 |
| Michon-Pasturel, U | 1 |
| Fauchais, AL | 1 |
| Delcey, V | 1 |
| Launay, D | 1 |
| Legout, L | 1 |
| Hachulla, E | 1 |
| Hatron, PY | 1 |
| Devulder, B | 1 |
| Lau, G | 1 |
| Kwan, C | 1 |
| Chong, SM | 1 |
| Griffiths, ID | 1 |
| Kane, SP | 1 |
| Yamakado, S | 1 |
| Yamada, T | 1 |
| Kishida, T | 1 |
| Nomura, T | 1 |
| Cantatore, FP | 1 |
| Carrozzo, M | 1 |
| Loperfido, MC | 1 |
| Deboever, G | 1 |
| Devogelaere, R | 1 |
| Holvoet, G | 1 |
| Labadie, H | 1 |
| Beaugrand, M | 1 |
| Ferrier, JP | 1 |
4 reviews available for sulfasalazine and Syndrome
| Article | Year |
|---|---|
[A case of salazosulfapyridine induced hypersensitivity syndrome].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Hypersensitivity; Female; Humans; Middle Aged; Sul | 2005 |
[Drug-induced hypersensitivity syndrome: DIHS].
Topics: Allopurinol; Anticonvulsants; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Herpesvirus 6, H | 2007 |
[A vertiginous syndrome due to sulfasalazine].
Topics: Adult; Colitis, Ulcerative; Female; Gastrointestinal Agents; Humans; Sulfasalazine; Syndrome; Vertig | 1999 |
Pulmonary infiltration and eosinophilia associated with sulfasalazine therapy for ulcerative colitis: a case report and review of literature.
Topics: Colitis, Ulcerative; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Male; Middle Aged; | 1992 |
1 trial available for sulfasalazine and Syndrome
| Article | Year |
|---|---|
[Flipping moxibustion of
Topics: Acupuncture Points; Antirheumatic Agents; Arthritis, Rheumatoid; Combined Modality Therapy; Humans; | 2017 |
32 other studies available for sulfasalazine and Syndrome
| Article | Year |
|---|---|
Drug-induced hypersensitivity syndrome in association with varicella.
Topics: Aged; Antirheumatic Agents; Chickenpox; Drug Hypersensitivity; Female; Herpesvirus 3, Human; Herpesv | 2015 |
Lymphoma-like presentation in suspected rheumatoid arthritis due to sulphasalazine hypersensitivity syndrome.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Diagnosis, Differential; Drug Eruptions; Drug Hy | 2008 |
Sulfasalazine-induced DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms).
Topics: Antirheumatic Agents; Arthritis; Drug Eruptions; Eosinophilia; Female; Humans; Middle Aged; Sulfasal | 2008 |
A case of sulphasalazine-induced DRESS syndrome with delayed acute interstitial nephritis.
Topics: Acute Disease; Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Eruption | 2009 |
Fulminant liver failure after vancomycin in a sulfasalazine-induced DRESS syndrome: fatal recurrence after liver transplantation.
Topics: Arthritis; Drug Hypersensitivity; Eosinophilia; Fas Ligand Protein; Fatal Outcome; Granzymes; Humans | 2009 |
Sulphasalazine induced three-week syndrome.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Edema; Exanthema; Female; Hum | 2009 |
Drug rash with eosinophilia and systemic symptoms syndrome induced by sulfasalazine.
Topics: Aged; Ampicillin; Anti-Bacterial Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Ceftriaxone; D | 2010 |
Epicutaneous patch testing in drug hypersensitivity syndrome (DRESS).
Topics: Allopurinol; Amoxicillin; Anticonvulsants; Drug Hypersensitivity; Eosinophilia; Exanthema; Female; H | 2010 |
[A case of hemophagocytic syndrome in an ulcerative colitis patient].
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Cells; Colitis | 2010 |
DRESS-syndrome on sulfasalazine and naproxen treatment for juvenile idiopathic arthritis and reactivation of human herpevirus 6 in an 11-year-old Caucasian boy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Drug Eruptions; Drug Therapy, C | 2010 |
[DRESS syndrome].
Topics: Adolescent; Adult; Allopurinol; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti | 2012 |
[DRESS syndrome as a result of sulfasalazine use].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Hypersensitivity; Eosinophilia; Exanthema; Female; Glu | 2010 |
Drug reaction with eosinophilia and systemic symptoms associated with H1N1 vaccination.
Topics: Antirheumatic Agents; Drug Eruptions; Eosinophilia; Female; Humans; Hypersensitivity, Delayed; Influ | 2012 |
A case of severe pulmonary infiltration with eosinophilia (PIE) syndrome induced by sulphasalazine.
Topics: Adrenal Cortex Hormones; Alveolitis, Extrinsic Allergic; Antirheumatic Agents; Arthritis; Drug Subst | 2012 |
Drug-induced hypersensitivity syndrome associated with human herpesvirus 6 and cytomegalovirus reactivation.
Topics: Aged; Cytomegalovirus; Cytomegalovirus Infections; Drug Hypersensitivity; Exanthema Subitum; Facial | 2005 |
[Drug hypersensitivity syndrome associated with a primary HHV6 infection].
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Drug Eruption | 2006 |
Sulphasalazine-induced DRESS.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Eruptions; Eosinophilia; Exanthema; Female; Humans; Mi | 2006 |
DRESS syndrome induced by sulphasalazine in rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Eruptions; Eosinophilia; Exanthema; Female; Humans | 2006 |
[Life-threatening liver failure and severe dyscrasias in blood and lymph nodes caused by sulphasalazine].
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Cell Count; Chemical and Drug Induced Live | 2006 |
[DRESS syndrome to sulfasalzine].
Topics: Adult; Antirheumatic Agents; Drug Hypersensitivity; Female; Humans; Sulfasalazine; Syndrome | 2006 |
[Case of ulcerative colitis associated with drug-induced hypersensitivity syndrome (DIHS) by salazosulfapyridine].
Topics: Adult; Betamethasone; Colitis, Ulcerative; Drug Hypersensitivity; Humans; Male; Methylprednisolone; | 2007 |
Sulfasalazine induced lupus in rheumatoid arthritis.
Topics: Aged; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Antinuclear; Antibody Specificity; Arthrit | 1994 |
Sapho syndrome with femoral hyperostosis. Two case-reports.
Topics: Adult; Antirheumatic Agents; Diphosphonates; Female; Femur; Humans; Hyperostosis; Magnetic Resonance | 1996 |
Severe hypersensitivity syndrome due to sulfasalazine associated with reactivation of human herpesvirus 6.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Hypersensitivity; Female; Herpesviridae Infecti | 1998 |
Photosensitivity with sulfasalazopyridine hypersensitivity syndrome.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Dermatitis, Photoallergic; Dru | 1999 |
Association of human herpesvirus 6 infection with drug reaction with eosinophilia and systemic symptoms.
Topics: Adult; Antibodies, Viral; Carbamazepine; DNA, Viral; Drug Eruptions; Eosinophilia; Herpesviridae Inf | 2001 |
[DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome after sulfasalazine and carmazepine: report of two cases].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants | 2001 |
The 3-week sulphasalazine syndrome strikes again.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Fatal Outcome; Female; Hepatitis; Humans; Myocar | 2001 |
Sulphasalazine-induced lupus syndrome in ulcerative colitis.
Topics: Colitis, Ulcerative; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Sulfasalazine; Synd | 1977 |
Post biliopancreatic bypass arthritis. Dermatitis syndrome.
Topics: Arthritis; Biliopancreatic Diversion; Dermatitis; Female; Humans; Methylprednisolone; Middle Aged; O | 1991 |
Sulphasalazine-induced lupus-like syndrome with cardiac tamponade in a patient with ulcerative colitis.
Topics: Cardiac Tamponade; Colitis, Ulcerative; Humans; Lupus Vulgaris; Male; Middle Aged; Sulfasalazine; Sy | 1989 |
[Hepatitis and mononucleosis syndrome related to the ingestion of salazosulfapyridine].
Topics: Adult; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Humans; Infectious Mononucle | 1986 |