Page last updated: 2024-11-04

sulfasalazine and Spondylitis

sulfasalazine has been researched along with Spondylitis in 11 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Spondylitis: Inflammation of the SPINE. This includes both arthritic and non-arthritic conditions.

Research Excerpts

ExcerptRelevanceReference
"Twenty-four patients with spondylitis and Crohn's disease or ulcerative colitis, treated with 5-ASA or sulfasalazine, were randomised and assessed by an investigator independent from the spa staff: 12 were submitted to a cycle of mud-bath treatment (12 mud packs and 12 thermal baths over a period of two weeks) and 12 were enrolled as controls."5.12Mud-bath treatment in spondylitis associated with inflammatory bowel disease--a pilot randomised clinical trial. ( Cardinale, G; Cozzi, F; Dani, L; Oliviero, F; Podswiadek, M; Punzi, L; Sfriso, P, 2007)
"Since reactive arthritis is induced by specific urogenital or enterogenic bacteriae, and since the gut is implicated in different forms of spondyloarthropathies, especially in IBD, it was clear that the gut could play an important role by permitting exogenous factors to enter the body."2.39The role of gut inflammation in the pathogenesis of spondyloarthropathies. ( Cuvelier, C; De Vos, M; Mielants, H; Veys, EM, 1996)
"Crohn's disease is a perplexing disease with a high rate of morbidity and complications."2.35The protean manifestations of Crohn's disease. ( Farmer, RG, 1975)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's4 (36.36)18.2507
2000's4 (36.36)29.6817
2010's0 (0.00)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Kostik, MM1
Kopchak, OL1
Maletin, AS1
Mushkin, AY1
Rodríguez-Reyna, TS1
Martínez-Reyes, C1
Yamamoto-Furusho, JK1
Cozzi, F1
Podswiadek, M1
Cardinale, G1
Oliviero, F1
Dani, L1
Sfriso, P1
Punzi, L1
Mielants, H3
Veys, EM3
Cuvelier, C2
De Vos, M2
Dougados, M1
Berenbaum, F1
Maetzel, A1
Amor, B1
Sieper, J1
Dekker-Saeys, BJ1
Dijkmans, BA1
Tytgat, GN1
Cacoub, P1
Sbaï, A1
Toan, SV1
Bellanger, J1
Hoang, C1
Godeau, P1
Piette, JC1
Farmer, RG1

Reviews

4 reviews available for sulfasalazine and Spondylitis

ArticleYear
Rheumatic manifestations of inflammatory bowel disease.
    World journal of gastroenterology, 2009, Nov-28, Volume: 15, Issue:44

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cadherins; Cytokines; Gastroenter

2009
[Significance of intestinal inflammation in the pathogenesis of spondylarthropathies].
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1996, Volume: 58, Issue:2

    Topics: Animals; Animals, Genetically Modified; Chronic Disease; Endoscopy, Gastrointestinal; HLA-B27 Antige

1996
The role of gut inflammation in the pathogenesis of spondyloarthropathies.
    Acta clinica Belgica, 1996, Volume: 51, Issue:5

    Topics: Anti-Inflammatory Agents; Arthritis, Reactive; Cell Membrane Permeability; Colonoscopy; HLA-B27 Anti

1996
The protean manifestations of Crohn's disease.
    Postgraduate medicine, 1975, Volume: 57, Issue:1

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Arthritis; Azathioprine; Child; Colectomy; Colitis,

1975

Trials

2 trials available for sulfasalazine and Spondylitis

ArticleYear
Mud-bath treatment in spondylitis associated with inflammatory bowel disease--a pilot randomised clinical trial.
    Joint bone spine, 2007, Volume: 74, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colitis, Ulcerative; Combined Modality Ther

2007
Treatment of spondyloarthropathy with 5-aminosalicylic acid (mesalazine): an open trial.
    The Journal of rheumatology, 2000, Volume: 27, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Blood Sedimentation; Female; H

2000

Other Studies

5 other studies available for sulfasalazine and Spondylitis

ArticleYear
The peculiarities and treatment outcomes of the spinal form of chronic non-bacterial osteomyelitis in children: a retrospective cohort study.
    Rheumatology international, 2020, Volume: 40, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Bone Density Conservation Agents; Case-Control Studies; Child; Chi

2020
Macroscopic and histological changes of the ileum HLA-B27 related diseases: therapeutic consequences.
    International journal of clinical pharmacology research, 1984, Volume: 4, Issue:6

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Child; Colonoscopy; HLA Antigens; HLA-B27 Antigen; Huma

1984
[Prevention of acute anterior uveitis associated with spondylarthropathy induced by salazosulfapyridine].
    Revue du rhumatisme (Ed. francaise : 1993), 1993, Volume: 60, Issue:1

    Topics: Adolescent; Adult; Child; Female; Humans; Male; Retrospective Studies; Spondylitis; Sulfasalazine; U

1993
[Basic therapeutics in the management of various forms of arthritis].
    Der Orthopade, 1998, Volume: 27, Issue:8

    Topics: Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Humans; Methotrexate; Poly

1998
[Collagenous colitis. A study of 11 cases].
    Annales de medecine interne, 2001, Volume: 152, Issue:5

    Topics: Adult; Agammaglobulinemia; Aged; Aged, 80 and over; Anemia; Anti-Inflammatory Agents; Anti-Inflammat

2001