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sulfasalazine and Spondylarthropathies

sulfasalazine has been researched along with Spondylarthropathies in 11 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Spondylarthropathies: Heterogeneous group of arthritic diseases sharing clinical and radiologic features. They are associated with the HLA-B27 ANTIGEN and some with a triggering infection. Most involve the axial joints in the SPINE, particularly the SACROILIAC JOINT, but can also involve asymmetric peripheral joints. Subsets include ANKYLOSING SPONDYLITIS; REACTIVE ARTHRITIS; PSORIATIC ARTHRITIS; and others.

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy and tolerability of single-agent sulfasalazine (SSZ) with combination therapies composed of SSZ and methotrexate (MTX) and SSZ, MTX and hydroxychloroquine (HCQ) in active spondyloarthropathy (SpA) patients with peripheral arthritis."5.11Combination therapies in spondyloarthropathies. ( Apraş, S; Calgüneri, M; Cobankara, V; Ertenli, I; Kiraz, S; Oztürk, MA, 2004)
"A young woman thought to have seronegative rheumatoid arthritis developed Stevens-Johnson syndrome after treatment with sulfasalazine; this resolved with prednisone."3.79Giant cell myocarditis in a patient with a spondyloarthropathy after a drug hypersensitivity reaction. ( Cooper, LT; Davies, RA; Grenon, J; Mesana, TG; Mielniczuk, LM; Mitoff, PR; Veinot, JP, 2013)
"Uveitis is a prevalent disease that mainly affects young people."2.43Uveitis. ( Martín-Mola, E; Muñoz-Fernández, S, 2006)
"We diagnosed late onset spondyloarthropathy according to clinic and radiographic findings."1.38Late onset spondyloarthropathy mimicking polymyalgia rheumatica. ( Altındağ, O; Aydeniz, A; Gürsoy, S; Oğüt, E, 2012)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Marino, A1
De Souza, M1
Giani, T1
Cimaz, R1
Rudwaleit, M1
Walscheid, K1
Heiligenhaus, A1
Mitoff, PR1
Mesana, TG1
Mielniczuk, LM1
Grenon, J1
Veinot, JP1
Cooper, LT1
Davies, RA1
MacMullan, PA1
Madigan, AM1
Paul, N1
Peace, AJ1
Alagha, A1
Nolan, KB1
McCarthy, GM1
Kenny, D1
Silva-Fernández, L1
Pérez-Vicente, S1
Martín-Martínez, MA1
López-González, R1
Aydeniz, A1
Altındağ, O1
Oğüt, E1
Gürsoy, S1
Kiratiseavee, S1
Brent, LH1
Calgüneri, M1
Cobankara, V1
Oztürk, MA1
Ertenli, I1
Kiraz, S1
Apraş, S1
Muñoz-Fernández, S1
Martín-Mola, E1
Scherer, HU1
Burmester, GR1
Stone, M1
Inman, RD1

Reviews

6 reviews available for sulfasalazine and Spondylarthropathies

ArticleYear
Pharmacotherapy for juvenile spondyloarthritis: an overview of the available therapies.
    Expert opinion on pharmacotherapy, 2020, Volume: 21, Issue:17

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Trials as Topic; Humans; Methotrex

2020
[Uveitis in spondyloarthritis].
    Zeitschrift fur Rheumatologie, 2017, Volume: 76, Issue:8

    Topics: Administration, Topical; Adrenal Cortex Hormones; Antirheumatic Agents; HLA-B27 Antigen; Humans; Int

2017
Spondyloarthropathies: using presentation to make the diagnosis.
    Cleveland Clinic journal of medicine, 2004, Volume: 71, Issue:3

    Topics: Antirheumatic Agents; Back Pain; Blood Sedimentation; C-Reactive Protein; Diagnosis, Differential; H

2004
Uveitis.
    Best practice & research. Clinical rheumatology, 2006, Volume: 20, Issue:3

    Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Disease

2006
[Biologicals in the treatment of rheumatic diseases].
    Deutsche medizinische Wochenschrift (1946), 2006, Oct-13, Volume: 131, Issue:41

    Topics: Abatacept; Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monocl

2006
Recent developments in the therapy of spondyloarthropathies.
    Current rheumatology reports, 2000, Volume: 2, Issue:4

    Topics: Alleles; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Monoclonal; Antirheumati

2000

Trials

1 trial available for sulfasalazine and Spondylarthropathies

ArticleYear
Combination therapies in spondyloarthropathies.
    The Kobe journal of medical sciences, 2004, Volume: 50, Issue:1-2

    Topics: Adult; Arthritis; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine; Male; Methotrexate;

2004

Other Studies

4 other studies available for sulfasalazine and Spondylarthropathies

ArticleYear
Giant cell myocarditis in a patient with a spondyloarthropathy after a drug hypersensitivity reaction.
    The Canadian journal of cardiology, 2013, Volume: 29, Issue:9

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Drug Hypersensitivity; Echocardiography;

2013
Sulfasalazine and its metabolites inhibit platelet function in patients with inflammatory arthritis.
    Clinical rheumatology, 2016, Volume: 35, Issue:2

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Platelets; Cohort Studies; Female; Humans;

2016
Variability in the prescription of non-biologic disease-modifying antirheumatic drugs for the treatment of spondyloarthritis in Spain.
    Seminars in arthritis and rheumatism, 2015, Volume: 44, Issue:6

    Topics: Adult; Antimalarials; Antirheumatic Agents; Azathioprine; Cohort Studies; Cyclophosphamide; Cyclospo

2015
Late onset spondyloarthropathy mimicking polymyalgia rheumatica.
    Rheumatology international, 2012, Volume: 32, Issue:5

    Topics: Age of Onset; Anti-Inflammatory Agents; Biomarkers; Blood Sedimentation; C-Reactive Protein; Diagnos

2012