sulfasalazine has been researched along with Spinal Diseases in 10 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Spinal Diseases: Diseases involving the SPINE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The disease RA itself is assumed to be a risk factor for the occurrence of adverse drug reactions during sulphasalazine therapy." | 2.38 | Rheumatoid arthritis: a risk factor for sulphasalazine toxicity? A meta-analysis. ( Van 'T Hof, MA; Van De Putte, LB; Van Riel, PL; Wijnands, MJ, 1993) |
| "Sulfasalazine has been evaluated by several groups of investigators in ankylosing spondylitis and psoriatic arthritis." | 2.38 | Medical and surgical treatment of seronegative spondyloarthropathies. ( Kozin, F, 1991) |
| "In addition to patients with RA or MCTD, focal sialadenitis also affects a very high proportion of patients with AS or SpA." | 1.31 | Focal sialadenitis in patients with ankylosing spondylitis and spondyloarthropathy: a comparison with patients with rheumatoid arthritis or mixed connective tissue disease. ( Helenius, I; Helenius, LM; Hietanen, JH; Kautiainen, H; Lappalainen, M; Leirisalo-Repo, M; Lindqvist, C; Paimela, L; Piirainen, H; Suuronen, R, 2001) |
| "To define a possible association between familial Mediterranean fever (FMF) and seronegative spondyloarthropathy (SNSA) and to study features of SNSA in FMF patients, we screened for the presence and manifestations of SNSA in 3,000 FMF patients attending the National Center for FMF in our institution." | 1.30 | Seronegative spondyloarthropathy in familial Mediterranean fever. ( Langevitz, P; Livneh, A; Pras, M; Shemer, J; Zemer, D, 1997) |
| "Sulfasalazine has a beneficial effect on articular activity by controlling gut inflammation, but it cannot prevent evolution to overt IBD." | 1.29 | Long-term evolution of gut inflammation in patients with spondyloarthropathy. ( Cuvelier, C; De Vos, M; Elewaut, A; Mielants, H; Veys, E, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (80.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, LL | 1 |
| Zhao, JX | 1 |
| Liu, XY | 1 |
| Wijnands, MJ | 1 |
| Van 'T Hof, MA | 1 |
| Van De Putte, LB | 1 |
| Van Riel, PL | 1 |
| De Vos, M | 1 |
| Mielants, H | 1 |
| Cuvelier, C | 1 |
| Elewaut, A | 1 |
| Veys, E | 1 |
| Njobvu, PD | 1 |
| McGill, PE | 1 |
| Langevitz, P | 1 |
| Livneh, A | 1 |
| Zemer, D | 1 |
| Shemer, J | 1 |
| Pras, M | 1 |
| Huang, JL | 1 |
| Chen, LC | 1 |
| Helenius, LM | 1 |
| Hietanen, JH | 1 |
| Helenius, I | 1 |
| Kautiainen, H | 1 |
| Piirainen, H | 1 |
| Paimela, L | 1 |
| Lappalainen, M | 1 |
| Suuronen, R | 1 |
| Lindqvist, C | 1 |
| Leirisalo-Repo, M | 1 |
| Dougados, M | 1 |
| Maetzel, A | 1 |
| Mijiyawa, M | 1 |
| Amor, B | 1 |
| Kozin, F | 1 |
| Simenon, G | 1 |
| Van Gossum, A | 1 |
| Adler, M | 1 |
| Rickaert, F | 1 |
| Appelboom, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Role of Gut Microbiota in the Pathogenesis of Ankylosing Spondylitis (AS), and the Effect of Fecal Microbiota Transplantation on Gut Microbiota, Gut Wall Inflammation and Clinical Activity of AS[NCT03726645] | Early Phase 1 | 20 participants (Actual) | Interventional | 2018-10-24 | Enrolling by invitation | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for sulfasalazine and Spinal Diseases
| Article | Year |
|---|---|
Rheumatoid arthritis: a risk factor for sulphasalazine toxicity? A meta-analysis.
Topics: Arthritis, Rheumatoid; Humans; Inflammatory Bowel Diseases; Risk Factors; Spinal Diseases; Sulfasala | 1993 |
Medical and surgical treatment of seronegative spondyloarthropathies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Behcet Syndrome; Humans; Joint Diseas | 1991 |
8 other studies available for sulfasalazine and Spinal Diseases
| Article | Year |
|---|---|
Successful treatment of SAPHO syndrome with severe spinal disorder using entercept: a case study.
Topics: Acquired Hyperostosis Syndrome; Alendronate; Antirheumatic Agents; Bone Density Conservation Agents; | 2012 |
Long-term evolution of gut inflammation in patients with spondyloarthropathy.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Enteritis; Fe | 1996 |
Sulphasalazine in the treatment of HIV-related spondyloarthropathy.
Topics: Adult; Female; HIV Infections; HIV-1; Humans; Joint Diseases; Male; Middle Aged; Spinal Diseases; Su | 1997 |
Seronegative spondyloarthropathy in familial Mediterranean fever.
Topics: Achilles Tendon; Adrenal Cortex Hormones; Adult; Ankle; Anti-Inflammatory Agents, Non-Steroidal; Ant | 1997 |
Sulphasalazine in the treatment of children with chronic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Clinical Trials as T | 1998 |
Focal sialadenitis in patients with ankylosing spondylitis and spondyloarthropathy: a comparison with patients with rheumatoid arthritis or mixed connective tissue disease.
Topics: Adult; Anti-Inflammatory Agents; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis; Arthritis | 2001 |
Evaluation of sulphasalazine in the treatment of spondyloarthropathies.
Topics: Adult; Drug Evaluation; Female; Humans; Joint Diseases; Male; Retrospective Studies; Spinal Diseases | 1992 |
Macroscopic and microscopic gut lesions in seronegative spondyloarthropathies.
Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents, Non-Steroidal; Colon; Colonoscopy; Female; Humans; | 1990 |