sulfasalazine has been researched along with Sjogren's Syndrome in 9 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Sjogren's Syndrome: Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulfasalazine was used because of its inhibitory effect on B cells." | 5.29 | [Sulfasalazine therapy for hypergammaglobulinemia in patients with Sjögren's syndrome]. ( Dohi, Y; Imai, F; Ishibashi, T; Ohno, S; Suzuki, T; Tanaka, M, 1994) |
| " The earlier use of methotrexate and the introduction of tumor necrosis factor-alpha inhibitors in the treatment of rheumatoid arthritis have changed the natural characteristics of the disease." | 4.87 | [Systemic autoimmune disorders and pregnancy]. ( Kiss, CG; Kiss, E; Poór, G, 2011) |
| "A 58-year-old woman with rheumatoid arthritis (RA) developed fever, skin eruptions, leukocytopenia, and thrombocytopenia, 3 weeks after treatment with sulfasalazine." | 3.74 | Sulfasalazine-induced hypersensitivity syndrome and hemophagocytic syndrome associated with reactivation of Epstein-Barr virus. ( Hatakeyama, T; Komatsuda, A; Okamoto, Y; Sawada, K; Wakui, H, 2008) |
| "Sjogren's syndrome and ankylosing spondylitis can occur either alone or in conjunction with other disorders." | 1.33 | Coexisting ankylosing spondylitis and Sjogren's syndrome: a case report. ( Cakirbay, H; Capkin, E; Guler, M; Karkucak, M; Topbas, M; Tosun, M, 2005) |
| "Sulfasalazine was used because of its inhibitory effect on B cells." | 1.29 | [Sulfasalazine therapy for hypergammaglobulinemia in patients with Sjögren's syndrome]. ( Dohi, Y; Imai, F; Ishibashi, T; Ohno, S; Suzuki, T; Tanaka, M, 1994) |
| "He had a previous history of selective IgA deficiency and ulcerative colitis treated with sulphasalazine." | 1.29 | Primary Sjögren's syndrome, ulcerative colitis and selective IgA deficiency. ( Colaco, CB; McCrea, DJ; Steuer, A, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kiss, E | 1 |
| Kiss, CG | 1 |
| Poór, G | 1 |
| Tosun, M | 1 |
| Karkucak, M | 1 |
| Capkin, E | 1 |
| Cakirbay, H | 1 |
| Guler, M | 1 |
| Topbas, M | 1 |
| Komatsuda, A | 1 |
| Okamoto, Y | 1 |
| Hatakeyama, T | 1 |
| Wakui, H | 1 |
| Sawada, K | 1 |
| Crisp, AJ | 1 |
| Hoffbrand, BI | 1 |
| Imai, F | 1 |
| Suzuki, T | 1 |
| Ishibashi, T | 1 |
| Ohno, S | 1 |
| Tanaka, M | 1 |
| Dohi, Y | 1 |
| Steuer, A | 1 |
| McCrea, DJ | 1 |
| Colaco, CB | 1 |
| Marinos, G | 1 |
| Riley, J | 1 |
| Painter, DM | 1 |
| McCaughan, GW | 1 |
| Merrin, P | 1 |
| Williams, IA | 1 |
| Bargon, J | 1 |
| Rust, M | 1 |
| Kardos, P | 1 |
| Schneider, M | 1 |
| Meier-Sydow, J | 1 |
2 reviews available for sulfasalazine and Sjogren's Syndrome
| Article | Year |
|---|---|
[Systemic autoimmune disorders and pregnancy].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Antiphospholipid Syndrome; Arthrit | 2011 |
Sulfasalazine-induced fulminant hepatic failure.
Topics: Adult; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Female; Hepatic Encephalopathy; | 1992 |
7 other studies available for sulfasalazine and Sjogren's Syndrome
| Article | Year |
|---|---|
Coexisting ankylosing spondylitis and Sjogren's syndrome: a case report.
Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non | 2005 |
Sulfasalazine-induced hypersensitivity syndrome and hemophagocytic syndrome associated with reactivation of Epstein-Barr virus.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Hypersensitivity; Epstein-Barr Virus Infections; F | 2008 |
Sulphasalazine-induced systemic lupus erythematosus in a patient with Sjögren's syndrome.
Topics: Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Sjogren's Syndrome; Sulfasalazine | 1980 |
[Sulfasalazine therapy for hypergammaglobulinemia in patients with Sjögren's syndrome].
Topics: Humans; Hypergammaglobulinemia; Immunoglobulin A; Immunoglobulin G; Sjogren's Syndrome; Sulfasalazin | 1994 |
Primary Sjögren's syndrome, ulcerative colitis and selective IgA deficiency.
Topics: Adolescent; Azathioprine; Colitis, Ulcerative; Gastrointestinal Agents; Humans; IgA Deficiency; Immu | 1996 |
Meningitis associated with sulphasalazine in a patient with Sjögren's syndrome and polyarthritis.
Topics: Adult; Arthritis; Drug Hypersensitivity; Female; Humans; Meningitis, Aseptic; Sjogren's Syndrome; Su | 1991 |
[Salazosulfapyridine-induced eosinophilic pneumonia with pulmonary and cutaneous epithelioid cell granulomatosis in Sjögren syndrome].
Topics: Aged; Female; Granuloma; Humans; Pulmonary Eosinophilia; Sjogren's Syndrome; Skin Diseases; Sulfasal | 1990 |