sulfasalazine has been researched along with Remission, Spontaneous in 19 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Remission, Spontaneous: A spontaneous diminution or abatement of a disease over time, without formal treatment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with ulcerative colitis in remission were randomly allocated to treatment with sulphasalazine (2 g/day) or oral sodium cromoglycate (160 mg/day or 2 g/day), and the relapse rates in these treatment groups were compared during continued treatment for one year." | 2.64 | Comparative trial of sulphasalazine and oral sodium cromoglycate in the maintenance of remission in ulcerative colitis. ( Dronfield, MW; Langman, MJ, 1978) |
| "It is concluded that maintenance treatment of ulcerative colitis with sulphasalazine should be continued indefinitely unless contraindicated by side effects." | 2.64 | A controlled therapeutic trial of long-term maintenance treatment of ulcerative colitis with sulphazalazine (Salazopyrin). ( Dissanayake, AS; Truelove, SC, 1973) |
| "Recurrences were more frequent in patients under than over 31 years of age at their first operation." | 1.26 | [Crohn's disease: course and prognosis in 169 patients (author's transl)]. ( Classen, M; Mörl, M; Zöberlein, HG, 1978) |
| "There were no deaths directly due to ulcerative colitis or to surgical treatment in these patients during the period of the study, the mean period of follow-up being 25 months; but 4 elderly patients died from unrelated causes." | 1.26 | Further experience in the treatment of severe attacks of ulcerative colitis. ( Kettlewell, MG; Lee, EG; Truelove, SC; Willoughby, CP, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sleisenger, MH | 1 |
| Klotz, U | 1 |
| Maier, K | 1 |
| Fischer, C | 1 |
| Heinkel, K | 1 |
| Davies, PS | 2 |
| Rhodes, J | 2 |
| Counsell, B | 1 |
| Evans, BK | 1 |
| Goldin, E | 1 |
| Rachmilewitz, D | 1 |
| Khosla, R | 1 |
| Willoughby, CP | 2 |
| Jewell, DP | 2 |
| Korelitz, BI | 1 |
| Sommers, SC | 1 |
| Langman, MJ | 2 |
| Dronfield, MW | 2 |
| Mörl, M | 1 |
| Zöberlein, HG | 1 |
| Classen, M | 1 |
| Truelove, SC | 3 |
| Lee, EG | 1 |
| Kettlewell, MG | 1 |
| Shakhbazian, AA | 1 |
| McPoland, PR | 1 |
| Moss, RL | 1 |
| Fairburn, RA | 1 |
| Dissanayake, AS | 1 |
| Fahrländer, H | 1 |
| Shalev, E | 1 |
| Hanke, P | 1 |
| Schulz, U | 1 |
| Das, KM | 1 |
| Eastwood, MA | 1 |
| Macmanus, JP | 1 |
| Sircus, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Botulinum Toxin Injections by Ultrasounds Guidance and Stretching Exercise in Spastic Toe Clawing[NCT02586142] | Phase 3 | 30 participants (Actual) | Interventional | 2010-08-31 | Completed | ||
| A Randomized, Multicenter Open Label Study Comparing Cyclosporine With Infliximab in Steroid-refractory Severe Attacks of Ulcerative Colitis[NCT00542152] | Phase 4 | 115 participants (Actual) | Interventional | 2007-06-30 | Completed | ||
| Dexamethasone Versus Methylprednisolone for the Treatment of Active Inflammatory Bowel Disease[NCT00152620] | 40 participants | Interventional | 2004-06-30 | Terminated (stopped due to study completed) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 trials available for sulfasalazine and Remission, Spontaneous
| Article | Year |
|---|---|
How should we treat Crohn's disease?
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Clinical Trials as Topic; Crohn Disease; Double-Blind | 1980 |
Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn's disease.
Topics: Adult; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Humans; M | 1980 |
Maintenance of remission in ulcerative colitis. Effect of an orally absorbed mast cell stabilizer.
Topics: Adult; Aged; Benzopyrans; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Colitis, Ulcerati | 1980 |
Prostanoids cytoprotection for maintaining remission in ulcerative colitis. Failure of 15(R), 15-methylprostaglandin E2.
Topics: Adult; Arbaprostil; Colitis, Ulcerative; Female; Humans; Male; Prostaglandins E, Synthetic; Remissio | 1983 |
Responses to drug therapy in ulcerative colitis. Evaluation by rectal biopsy and histopathological changes.
Topics: Biopsy; Clinical Trials as Topic; Colitis, Ulcerative; Drug Evaluation; Drug Therapy, Combination; H | 1975 |
Disodium cromoglycate maintenance treatment of ulcerative colitis.
Topics: Clinical Trials as Topic; Colitis, Ulcerative; Cromolyn Sodium; Drug Evaluation; Humans; Placebos; P | 1977 |
Maintenance of remission in ulcerative colitis with sulphasalazine or a high-fibre diet: a clinical trial.
Topics: Adult; Cellulose; Clinical Trials as Topic; Colitis, Ulcerative; Dietary Fiber; Humans; Recurrence; | 1978 |
Comparative trial of sulphasalazine and oral sodium cromoglycate in the maintenance of remission in ulcerative colitis.
Topics: Adult; Clinical Trials as Topic; Colitis, Ulcerative; Cromolyn Sodium; Dose-Response Relationship, D | 1978 |
A controlled therapeutic trial of long-term maintenance treatment of ulcerative colitis with sulphazalazine (Salazopyrin).
Topics: Biopsy; Blood Cell Count; Blood Sedimentation; Clinical Trials as Topic; Colitis, Ulcerative; Headac | 1973 |
[Experiences with the rectal azulfidine therapy].
Topics: Biopsy; Colitis, Ulcerative; Humans; Intestinal Mucosa; Placebos; Proctoscopy; Rectum; Remission, Sp | 1971 |
9 other studies available for sulfasalazine and Remission, Spontaneous
| Article | Year |
|---|---|
Crohn's disease and pregnancy.
Topics: Abortion, Spontaneous; Adrenal Cortex Hormones; Adult; Crohn Disease; Female; Fertility; Humans; Pre | 1984 |
[Crohn's disease: course and prognosis in 169 patients (author's transl)].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Body Weight; Child; Child, Preschool; | 1978 |
Further experience in the treatment of severe attacks of ulcerative colitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amino Acids; Azathioprine; Child; Child, Preschool; C | 1978 |
[Experience in treating nonspecific ulcerative colitis].
Topics: Colitis, Ulcerative; Diet Therapy; Drug Therapy, Combination; Humans; Plant Extracts; Remission, Spo | 1975 |
Cutaneous Crohn's disease and progressive vitiligo.
Topics: Adult; Colonic Diseases; Crohn Disease; Female; Granuloma; Humans; Remission, Spontaneous; Skin Dise | 1988 |
On the aetiology of ulcerative colitis. A vascular hypothesis.
Topics: Adult; Age Factors; Animals; Child; Colitis, Ulcerative; Diarrhea; Dogs; Female; Gastrointestinal Mo | 1973 |
Intensive intravenous regimen for severe attacks of ulcerative colitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Ascorbic Acid; Child; Colitis, Ulcerative; Drug Thera | 1974 |
[Ulcerative colitis. Follow-up study of 160 patients observed for an average of 10 and one-half years (author's transl)].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Child; Child, Preschool; Colectomy; Colitis, Ulcer | 1974 |
Salazopyrin metabolism in ulcerative colitis.
Topics: Colitis, Ulcerative; Humans; Remission, Spontaneous; Sulfasalazine; Sulfonamides | 1972 |