sulfasalazine has been researched along with Proctitis in 36 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Proctitis: INFLAMMATION of the MUCOUS MEMBRANE of the RECTUM, the distal end of the large intestine (INTESTINE, LARGE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind therapeutic trial of azathioprine in 20 patients with acute proctocolitis was performed over a 3-month period." | 9.04 | Double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis. Preliminary report. ( Babbini, M; Caprilli, R; Carratù, R, 1975) |
| "Most patients ultimately experienced a recurrence of symptoms, but the duration of remission was significantly longer with maintenance oral sulfasalazine or mesalamine (17." | 5.28 | Maintenance oral sulfasalazine prolongs remission in ulcerative proctitis and proctosigmoiditis. ( Bodian, C; LaRosa, D; Present, DH; Rubin, PH, 1991) |
| "In severe forms of ulcerative colitis and idiopathic proctitis circulating EAC-phagocytosing esterase positive cells, indicative of activated monocytes, were demonstrated." | 5.26 | Comparative analysis of systemic immunological parameters in ulcerative colitis and idiopathic proctitis: effects of sulfasalazine in vivo and in vitro. ( Das, KM; Melamed, J; Murphy, RA; Rubinstein, A, 1978) |
| "A double-blind therapeutic trial of azathioprine in 20 patients with acute proctocolitis was performed over a 3-month period." | 5.04 | Double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis. Preliminary report. ( Babbini, M; Caprilli, R; Carratù, R, 1975) |
| " The conversion of cholesterol to coprostanol, the production of urobilinogen, and the degradation of tryptic activity (FTA) and beta-aspartylglycine were measured in faecal samples from patients with proctitis or left-sided or total ulcerative colitis and in age- and sex-matched controls." | 3.68 | Functional alterations of the microflora in patients with ulcerative colitis. ( Benno, P; Leijonmarck, CE; Midtvedt, T; Monsén, U; Uribe, A, 1993) |
| "Most patients ultimately experienced a recurrence of symptoms, but the duration of remission was significantly longer with maintenance oral sulfasalazine or mesalamine (17." | 1.28 | Maintenance oral sulfasalazine prolongs remission in ulcerative proctitis and proctosigmoiditis. ( Bodian, C; LaRosa, D; Present, DH; Rubin, PH, 1991) |
| "Ulcerative proctitis is a non-specific inflammatory condition of a diffuse nature involving the mucosa of the rectum." | 1.26 | Ulcerative proctitis. ( Buls, J, 1980) |
| "In severe forms of ulcerative colitis and idiopathic proctitis circulating EAC-phagocytosing esterase positive cells, indicative of activated monocytes, were demonstrated." | 1.26 | Comparative analysis of systemic immunological parameters in ulcerative colitis and idiopathic proctitis: effects of sulfasalazine in vivo and in vitro. ( Das, KM; Melamed, J; Murphy, RA; Rubinstein, A, 1978) |
| "Patients with proctocolitis and Crohn's disease who were not receiving sulphasalazine had a similar flora which did not differ in any way from the normal." | 1.25 | Effects of sulphasalazine (Salazopyrin) on faecal flora in patients with inflammatory bowel disease. ( Hill, MJ; Lendrum, R; Walker, G; West, B, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (86.11) | 18.7374 |
| 1990's | 3 (8.33) | 18.2507 |
| 2000's | 1 (2.78) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abdou, A | 1 |
| Zaouri, H | 1 |
| El Moussaoui, N | 1 |
| Senouci, K | 1 |
| Hassam, B | 1 |
| Ismaili, N | 1 |
| ANTHONISEN, P | 1 |
| RIIS, P | 1 |
| Buls, J | 1 |
| van Hees, PA | 2 |
| Bakker, JH | 2 |
| van Tongeren, JH | 2 |
| Boëtius, G | 1 |
| Stuurman, A | 1 |
| Bol, J | 1 |
| Frühmorgen, P | 1 |
| Demling, L | 1 |
| Gallone, L | 1 |
| Olmi, L | 1 |
| Marchetti, V | 1 |
| Allan, RN | 1 |
| Schütze, K | 1 |
| Hentschel, E | 1 |
| McCarthy, CF | 1 |
| Van de Pette, JE | 1 |
| Cunnah, DT | 1 |
| Shallcross, TM | 1 |
| Benno, P | 1 |
| Leijonmarck, CE | 1 |
| Monsén, U | 1 |
| Uribe, A | 1 |
| Midtvedt, T | 1 |
| Toyoda, H | 1 |
| Yamaguchi, M | 1 |
| Uemura, Y | 1 |
| Mukai, K | 1 |
| Sawa, H | 1 |
| Suzuki, H | 1 |
| Shiku, H | 1 |
| Chevrel, B | 1 |
| Das, KM | 2 |
| Morecki, R | 1 |
| Nair, P | 1 |
| Berkowitz, JM | 1 |
| Fahrländer, H | 2 |
| Kane, SP | 1 |
| Boots, MA | 1 |
| Henrikson, B | 1 |
| Hultén, L | 1 |
| Filipson, S | 1 |
| Sillĕn, U | 1 |
| Rubinstein, A | 1 |
| Melamed, J | 1 |
| Murphy, RA | 1 |
| Dyring-Andersen, K | 1 |
| Sparsø, BH | 1 |
| Kragelund, E | 1 |
| Bonnevie, O | 1 |
| van Lier, HJ | 1 |
| Caprilli, R | 1 |
| Carratù, R | 1 |
| Babbini, M | 1 |
| Goldman, P | 1 |
| Peppercorn, MA | 1 |
| Modigliani, R | 1 |
| LaRosa, D | 1 |
| Rubin, PH | 1 |
| Bodian, C | 1 |
| Present, DH | 1 |
| Janowitz, HD | 1 |
| Ewe, K | 1 |
| Eckardt, V | 1 |
| Kanzler, G | 1 |
| Schulz, U | 1 |
| Hanke, P | 1 |
| Seige, K | 1 |
| McKechnie, JC | 1 |
| Bynum, TE | 1 |
| Bentlif, PS | 1 |
| Lanza, FL | 1 |
| Shalev, E | 1 |
| West, B | 1 |
| Lendrum, R | 1 |
| Hill, MJ | 1 |
| Walker, G | 1 |
| Kaufmann, W | 1 |
| Wilson, E | 1 |
| Lisewski, G | 1 |
| David, H | 1 |
| Wilke, E | 1 |
| Köhler, W | 1 |
| Jacobs, H | 1 |
| Rindt, W | 1 |
| Schmid, N | 1 |
| Vuillet, F | 1 |
| Saegesser, F | 1 |
| Justafre, JC | 1 |
| Phillips, V | 1 |
| Fasel, J | 1 |
3 reviews available for sulfasalazine and Proctitis
| Article | Year |
|---|---|
[NONSPECIFIC HEMORRHAGIC PROCTOCOLITIC (ULCERATIVE COLITIS AND HEMORRHAGIC PROCTITIS): MEDICAL DIAGNOSIS AND TREATMENT].
Topics: Adrenal Cortex Hormones; Biopsy; Colitis; Colitis, Ulcerative; Cytodiagnosis; Diagnosis; Gastrointes | 1964 |
Drug therapy: Sulfasalazine.
Topics: Animals; Bacteria; Binding, Competitive; Biological Transport; Chemical Phenomena; Chemistry; Coliti | 1975 |
[Treatment of hemorrhagic rectocolitis].
Topics: Colectomy; Colitis, Ulcerative; Colostomy; Drug Combinations; Glucosamine; Humans; Ileostomy; Procti | 1991 |
6 trials available for sulfasalazine and Proctitis
| Article | Year |
|---|---|
Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: a study to determine the active therapeutic moiety of sulphasalazine.
Topics: Adult; Aminosalicylic Acids; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Middle Age | 1980 |
On the efficacy of ready-made-up commercially available salicylazosulphapyridine enemas in the treatment of proctitis, proctosigmoiditis and ulcerative colitis involving rectum, sigmoid and descending colon.
Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Colitis; Colitis, Ulcerative; Double-Bl | 1980 |
Active therapeutic moiety of sulphasalazine.
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Drug Evaluation; Humans; Placebos; Proctitis; Random | 1978 |
Double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis. Preliminary report.
Topics: Acute Disease; Adolescent; Adult; Aged; Azathioprine; Biopsy; Clinical Trials as Topic; Colitis; Dru | 1975 |
Treatment of ulcerative colitis with olsalazine and sulphasalazine: efficacy and side-effects.
Topics: Adult; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Double-Blind Method; Fem | 1988 |
[Rectal effect of salazopyrine in ulcerative colitis during a double-blind study].
Topics: Chronic Disease; Colitis, Ulcerative; Diverticulitis, Colonic; Enema; Female; Humans; Intestinal Muc | 1973 |
27 other studies available for sulfasalazine and Proctitis
| Article | Year |
|---|---|
[Crohn's disease: Vulvar edema and swelling].
Topics: Adrenal Cortex Hormones; Anus Diseases; Crohn Disease; Drug Combinations; Drug Substitution; Edema; | 2016 |
Ulcerative proctitis.
Topics: Colitis, Ulcerative; Diagnosis, Differential; Humans; Proctitis; Sulfasalazine; Ulcer | 1980 |
[Male infertility during treatment with salazosulfapyridine].
Topics: Adult; Crohn Disease; Humans; Infertility, Male; Male; Proctitis; Sulfasalazine | 1980 |
Use of topical rectal therapy to preserve the rectum in surgery of ulcerative colitis.
Topics: Administration, Topical; Adult; Aged; Colitis, Ulcerative; Dexamethasone; Drug Therapy, Combination; | 1980 |
Sodium cromoglycate in proctitis and ulcerative colitis.
Topics: Colitis, Ulcerative; Cromolyn Sodium; Drug Hypersensitivity; Humans; Proctitis; Sulfasalazine | 1982 |
[Clinical picture and therapy of nonspecific ulcerative proctitis (author's transl)].
Topics: Colon, Sigmoid; Enema; Female; Humans; Male; Proctitis; Prognosis; Rectum; Recurrence; Sulfasalazine | 1982 |
Drug management of inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antidiarrheals; Azathio | 1983 |
Bone marrow necrosis after treatment with sulphasalazine.
Topics: Adult; Bone Marrow; Humans; Male; Necrosis; Proctitis; Sulfasalazine | 1984 |
Functional alterations of the microflora in patients with ulcerative colitis.
Topics: Adult; Cholestanol; Cholesterol; Colitis, Ulcerative; Dipeptides; Feces; Female; Humans; Male; Middl | 1993 |
Successful treatment of lymphoid follicular proctitis with sulfasalazine suppositories.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Colonoscopy; Diagnosis, Differential; Female; Human | 2000 |
[Inflammatory diseases of the colon and salazopyrine. Value of long term treatment].
Topics: Chemical Phenomena; Chemistry; Colitis; Colonic Diseases; Crohn Disease; Female; Gastrointestinal He | 1976 |
Idiopathic proctitis. I. The morphology of proximal colonic mucosa and its clinical significance.
Topics: Adult; Aged; Colon; Endoscopy; Enema; Female; Humans; Hydrocortisone; Intestinal Mucosa; Male; Middl | 1977 |
[Chronic-inflammatory intestinal diseases. Clinical picture, complications, differential diagnosis and nonsurgical therapy].
Topics: Adrenal Cortex Hormones; Azathioprine; Chronic Disease; Colitis, Ulcerative; Crohn Disease; Diagnosi | 1977 |
Megaloblastic anaemia associated with sulphasalazine treatment.
Topics: Adult; Anemia, Macrocytic; Female; Folic Acid Deficiency; Humans; Proctitis; Sulfasalazine; Ulcer | 1977 |
Long-term study of the effect of treatment for ulcerative colitis.
Topics: Adolescent; Body Weight; Child; Colitis, Ulcerative; Colon; Cortisone; Female; Humans; Male; Proctit | 1978 |
Comparative analysis of systemic immunological parameters in ulcerative colitis and idiopathic proctitis: effects of sulfasalazine in vivo and in vitro.
Topics: Adult; Colitis, Ulcerative; Female; Humans; Immunoglobulins; In Vitro Techniques; Leukocyte Count; L | 1978 |
[Prognosis in hemorrhagic proctitis].
Topics: Adult; Female; Gastrointestinal Hemorrhage; Glucocorticoids; Humans; Male; Middle Aged; Proctitis; P | 1978 |
Maintenance oral sulfasalazine prolongs remission in ulcerative proctitis and proctosigmoiditis.
Topics: Adolescent; Adult; Aged; Child; Colitis, Ulcerative; Female; Humans; Male; Middle Aged; Proctitis; R | 1991 |
1986 Stuart distinguished lecture. The "natural history" of inflammatory bowel disease and therapeutic decisions.
Topics: Adrenocorticotropic Hormone; Colectomy; Colitis, Ulcerative; Colon; Cortisone; Crohn Disease; Dilata | 1987 |
Ulcerative proctitis.
Topics: Adolescent; Adult; Biopsy; Colitis, Ulcerative; Cortisone; Diagnosis, Differential; Diazepam; Female | 1974 |
[Ulcerative colitis. Follow-up study of 160 patients observed for an average of 10 and one-half years (author's transl)].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Child; Child, Preschool; Colectomy; Colitis, Ulcer | 1974 |
Effects of sulphasalazine (Salazopyrin) on faecal flora in patients with inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aged; Bacteroides; Clostridium; Colitis | 1974 |
[Rectitis (rectosigmoiditis, rare rectocolitis hemorrhagica) in ambulant gastroenterologic metropolitan practice, 37 cases in about 10,000 first admissions].
Topics: Adult; Aged; Colitis; Colon, Sigmoid; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; | 1967 |
"Salazopyrin" in the treatment of granular proctitis.
Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Proctitis; Sulfasalazine | 1970 |
[First experiences with serial biopsy of the rectal mucosa in inflammatory rectal-colonic diseases].
Topics: Adrenocorticotropic Hormone; Biopsy; Colitis; Colitis, Ulcerative; Colonic Diseases; Humans; Intesti | 1970 |
[Treatment of radiation proctitis].
Topics: Administration, Oral; Adult; Aged; Fecal Incontinence; Female; Genital Neoplasms, Female; Humans; Me | 1971 |
[Considerations on the ulcerative-hemorrhagic rectocolitis].
Topics: Adrenal Cortex Hormones; Colitis, Ulcerative; Diet Therapy; Gastrointestinal Hemorrhage; Humans; Pro | 1972 |