sulfasalazine has been researched along with Precancerous Conditions in 5 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Precancerous Conditions: Pathological conditions that tend eventually to become malignant.
| Excerpt | Relevance | Reference |
|---|---|---|
| " It has recently been suggested that presence of primary sclerosing cholangitis is another independent risk factor-especially for proximal colorectal dysplasia or cancer-and that treatment with sulfasalazine might reduce the frequency of colorectal cancer in ulcerative colitis; the present study was undertaken to shed light on the validity of these theories." | 3.71 | Proximal colorectal dysplasia or cancer in ulcerative colitis. The impact of primary sclerosing cholangitis and sulfasalazine: results from a 20-year surveillance study. ( Broomé, U; Lindberg, BU; Persson, B, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shimizu, T | 1 |
| Sohn, Y | 1 |
| Choi, E | 1 |
| Petersen, CP | 1 |
| Prasad, N | 1 |
| Goldenring, JR | 1 |
| Wada, T | 1 |
| Ishimoto, T | 1 |
| Seishima, R | 1 |
| Tsuchihashi, K | 1 |
| Yoshikawa, M | 1 |
| Oshima, H | 1 |
| Oshima, M | 1 |
| Masuko, T | 1 |
| Wright, NA | 1 |
| Furuhashi, S | 1 |
| Hirashima, K | 1 |
| Baba, H | 1 |
| Kitagawa, Y | 1 |
| Saya, H | 1 |
| Nagano, O | 1 |
| Rubin, DT | 1 |
| LoSavio, A | 1 |
| Yadron, N | 1 |
| Huo, D | 1 |
| Hanauer, SB | 1 |
| Jess, T | 1 |
| Loftus, EV | 1 |
| Velayos, FS | 1 |
| Winther, KV | 1 |
| Tremaine, WJ | 1 |
| Zinsmeister, AR | 1 |
| Scott Harmsen, W | 1 |
| Langholz, E | 1 |
| Binder, V | 1 |
| Munkholm, P | 1 |
| Sandborn, WJ | 1 |
| Lindberg, BU | 1 |
| Broomé, U | 1 |
| Persson, B | 1 |
5 other studies available for sulfasalazine and Precancerous Conditions
| Article | Year |
|---|---|
Decrease in MiR-148a Expression During Initiation of Chief Cell Transdifferentiation.
Topics: Amino Acid Transport System y+; Animals; Atrophy; Cell Line; Cell Transdifferentiation; Chief Cells, | 2020 |
Functional role of CD44v-xCT system in the development of spasmolytic polypeptide-expressing metaplasia.
Topics: Adenocarcinoma; Amino Acid Transport System y+; Animals; Biomarkers, Tumor; Cell Transformation, Neo | 2013 |
Aminosalicylate therapy in the prevention of dysplasia and colorectal cancer in ulcerative colitis.
Topics: Adult; Aminosalicylic Acids; Case-Control Studies; Chemoprevention; Chronic Disease; Colitis, Ulcera | 2006 |
Risk factors for colorectal neoplasia in inflammatory bowel disease: a nested case-control study from Copenhagen county, Denmark and Olmsted county, Minnesota.
Topics: Adult; Case-Control Studies; Colonoscopy; Colorectal Neoplasms; Denmark; Female; Gastrointestinal Ag | 2007 |
Proximal colorectal dysplasia or cancer in ulcerative colitis. The impact of primary sclerosing cholangitis and sulfasalazine: results from a 20-year surveillance study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cholangitis, Sclerosing; Co | 2001 |