Page last updated: 2024-11-04

sulfasalazine and Precancerous Conditions

sulfasalazine has been researched along with Precancerous Conditions in 5 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Precancerous Conditions: Pathological conditions that tend eventually to become malignant.

Research Excerpts

ExcerptRelevanceReference
" It has recently been suggested that presence of primary sclerosing cholangitis is another independent risk factor-especially for proximal colorectal dysplasia or cancer-and that treatment with sulfasalazine might reduce the frequency of colorectal cancer in ulcerative colitis; the present study was undertaken to shed light on the validity of these theories."3.71Proximal colorectal dysplasia or cancer in ulcerative colitis. The impact of primary sclerosing cholangitis and sulfasalazine: results from a 20-year surveillance study. ( Broomé, U; Lindberg, BU; Persson, B, 2001)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Shimizu, T1
Sohn, Y1
Choi, E1
Petersen, CP1
Prasad, N1
Goldenring, JR1
Wada, T1
Ishimoto, T1
Seishima, R1
Tsuchihashi, K1
Yoshikawa, M1
Oshima, H1
Oshima, M1
Masuko, T1
Wright, NA1
Furuhashi, S1
Hirashima, K1
Baba, H1
Kitagawa, Y1
Saya, H1
Nagano, O1
Rubin, DT1
LoSavio, A1
Yadron, N1
Huo, D1
Hanauer, SB1
Jess, T1
Loftus, EV1
Velayos, FS1
Winther, KV1
Tremaine, WJ1
Zinsmeister, AR1
Scott Harmsen, W1
Langholz, E1
Binder, V1
Munkholm, P1
Sandborn, WJ1
Lindberg, BU1
Broomé, U1
Persson, B1

Other Studies

5 other studies available for sulfasalazine and Precancerous Conditions

ArticleYear
Decrease in MiR-148a Expression During Initiation of Chief Cell Transdifferentiation.
    Cellular and molecular gastroenterology and hepatology, 2020, Volume: 9, Issue:1

    Topics: Amino Acid Transport System y+; Animals; Atrophy; Cell Line; Cell Transdifferentiation; Chief Cells,

2020
Functional role of CD44v-xCT system in the development of spasmolytic polypeptide-expressing metaplasia.
    Cancer science, 2013, Volume: 104, Issue:10

    Topics: Adenocarcinoma; Amino Acid Transport System y+; Animals; Biomarkers, Tumor; Cell Transformation, Neo

2013
Aminosalicylate therapy in the prevention of dysplasia and colorectal cancer in ulcerative colitis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2006, Volume: 4, Issue:11

    Topics: Adult; Aminosalicylic Acids; Case-Control Studies; Chemoprevention; Chronic Disease; Colitis, Ulcera

2006
Risk factors for colorectal neoplasia in inflammatory bowel disease: a nested case-control study from Copenhagen county, Denmark and Olmsted county, Minnesota.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:4

    Topics: Adult; Case-Control Studies; Colonoscopy; Colorectal Neoplasms; Denmark; Female; Gastrointestinal Ag

2007
Proximal colorectal dysplasia or cancer in ulcerative colitis. The impact of primary sclerosing cholangitis and sulfasalazine: results from a 20-year surveillance study.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cholangitis, Sclerosing; Co

2001