sulfasalazine has been researched along with Pouchitis in 3 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Pouchitis: Acute INFLAMMATION in the INTESTINAL MUCOSA of the continent ileal reservoir (or pouch) in patients who have undergone ILEOSTOMY and restorative proctocolectomy (PROCTOCOLECTOMY, RESTORATIVE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the hypothesis that sulfasalazine (SASP) might have a synergistic beneficial effect in acute pouchitis, by combining the anti-inflammatory activity of 5-aminosalicylic Acid and the bacteriostatic effect of sulphapyridine." | 9.14 | Pilot study: the use of sulfasalazine for the treatment of acute pouchitis. ( Belluzzi, A; Bianchi, ML; Castellani, L; Grazia, M; Roda, E; Roda, G; Rosati, G; Serrani, M; Ugolini, G, 2010) |
| "The aim of this study was to retrospectively evaluate the effect of sulfasalazine in primary prophylaxis of pouchitis after proctocolectomy with ileal pouch-anal anastomosis." | 7.85 | Sulfasalazine in Prevention of Pouchitis After Proctocolectomy with Ileal Pouch-Anal Anastomosis for Ulcerative Colitis. ( Bazzoli, F; Belluzzi, A; Digby, RJ; Festi, D; Liverani, E; Poggioli, G; Rosati, G; Sartini, A; Scaioli, E; Ugolini, G, 2017) |
| "To test the hypothesis that sulfasalazine (SASP) might have a synergistic beneficial effect in acute pouchitis, by combining the anti-inflammatory activity of 5-aminosalicylic Acid and the bacteriostatic effect of sulphapyridine." | 5.14 | Pilot study: the use of sulfasalazine for the treatment of acute pouchitis. ( Belluzzi, A; Bianchi, ML; Castellani, L; Grazia, M; Roda, E; Roda, G; Rosati, G; Serrani, M; Ugolini, G, 2010) |
| "The aim of this study was to retrospectively evaluate the effect of sulfasalazine in primary prophylaxis of pouchitis after proctocolectomy with ileal pouch-anal anastomosis." | 3.85 | Sulfasalazine in Prevention of Pouchitis After Proctocolectomy with Ileal Pouch-Anal Anastomosis for Ulcerative Colitis. ( Bazzoli, F; Belluzzi, A; Digby, RJ; Festi, D; Liverani, E; Poggioli, G; Rosati, G; Sartini, A; Scaioli, E; Ugolini, G, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scaioli, E | 1 |
| Sartini, A | 1 |
| Liverani, E | 1 |
| Digby, RJ | 1 |
| Ugolini, G | 2 |
| Rosati, G | 2 |
| Poggioli, G | 1 |
| Festi, D | 1 |
| Bazzoli, F | 1 |
| Belluzzi, A | 2 |
| Serrani, M | 1 |
| Roda, G | 1 |
| Bianchi, ML | 1 |
| Castellani, L | 1 |
| Grazia, M | 1 |
| Roda, E | 1 |
| Olivieri, I | 1 |
| Padula, A | 1 |
| Scarano, E | 1 |
| Gionchetti, P | 1 |
1 trial available for sulfasalazine and Pouchitis
| Article | Year |
|---|---|
Pilot study: the use of sulfasalazine for the treatment of acute pouchitis.
Topics: Adult; Colonic Pouches; Female; Humans; Intestinal Mucosa; Male; Mesalamine; Middle Aged; Pilot Proj | 2010 |
2 other studies available for sulfasalazine and Pouchitis
| Article | Year |
|---|---|
Sulfasalazine in Prevention of Pouchitis After Proctocolectomy with Ileal Pouch-Anal Anastomosis for Ulcerative Colitis.
Topics: Adolescent; Adult; Aged; Anal Canal; Anastomosis, Surgical; Colitis, Ulcerative; Colonic Pouches; Fe | 2017 |
Ileal pouchitis-related arthritis.
Topics: Antirheumatic Agents; Arthritis, Infectious; Colitis, Ulcerative; Colonic Pouches; Female; Glucocort | 2002 |