sulfasalazine has been researched along with Pneumonia, Pneumocystis in 6 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Pneumonia, Pneumocystis: A pulmonary disease in humans occurring in immunodeficient or malnourished patients or infants, characterized by DYSPNEA, tachypnea, and HYPOXEMIA. Pneumocystis pneumonia is a frequently seen opportunistic infection in AIDS. It is caused by the fungus PNEUMOCYSTIS JIROVECII. The disease is also found in other MAMMALS where it is caused by related species of Pneumocystis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the prophylactic effect of sulfasalazine against Pneumocystis jirovecii pneumonia (PJP) among rheumatoid arthritis (RA) patients." | 7.91 | Prophylactic effect of sulfasalazine against Pneumocystis pneumonia in patients with rheumatoid arthritis: A nested case-control study. ( Gosho, M; Nishino, J; Nunokawa, T; Shimada, K; Sugii, S; Tohma, S; Wagatsuma, Y; Yokogawa, N, 2019) |
| "Sulfasalazine use was associated with a decreased PCP risk (adjusted IRR <0." | 5.91 | Efficacy of sulfasalazine for the prevention of Pneumocystis pneumonia in patients with rheumatoid arthritis: A multicentric self-controlled case series study. ( Chen, FY; Chinen, N; Kimura, M; Nunokawa, T; Setoguchi, K; Shimada, K; Sugihara, M; Tateishi, M, 2023) |
| "To evaluate the prophylactic effect of sulfasalazine against Pneumocystis jirovecii pneumonia (PJP) among rheumatoid arthritis (RA) patients." | 3.91 | Prophylactic effect of sulfasalazine against Pneumocystis pneumonia in patients with rheumatoid arthritis: A nested case-control study. ( Gosho, M; Nishino, J; Nunokawa, T; Shimada, K; Sugii, S; Tohma, S; Wagatsuma, Y; Yokogawa, N, 2019) |
| "Sulfasalazine use was associated with a decreased PCP risk (adjusted IRR <0." | 1.91 | Efficacy of sulfasalazine for the prevention of Pneumocystis pneumonia in patients with rheumatoid arthritis: A multicentric self-controlled case series study. ( Chen, FY; Chinen, N; Kimura, M; Nunokawa, T; Setoguchi, K; Shimada, K; Sugihara, M; Tateishi, M, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Nunokawa, T | 3 |
| Chinen, N | 1 |
| Shimada, K | 3 |
| Kimura, M | 1 |
| Tateishi, M | 1 |
| Chen, FY | 1 |
| Setoguchi, K | 1 |
| Sugihara, M | 1 |
| Hoy, Z | 1 |
| Wright, TW | 2 |
| Elliott, M | 1 |
| Malone, J | 1 |
| Bhagwat, S | 1 |
| Wang, J | 2 |
| Gigliotti, F | 2 |
| Yokogawa, N | 2 |
| Sugii, S | 2 |
| Nishino, J | 1 |
| Gosho, M | 1 |
| Wagatsuma, Y | 1 |
| Tohma, S | 1 |
| Bhagwat, SP | 1 |
| George, TC | 1 |
| Khatchatourian, M | 1 |
| Seaton, TL | 1 |
6 other studies available for sulfasalazine and Pneumonia, Pneumocystis
| Article | Year |
|---|---|
Efficacy of sulfasalazine for the prevention of Pneumocystis pneumonia in patients with rheumatoid arthritis: A multicentric self-controlled case series study.
Topics: Arthritis, Rheumatoid; Humans; Methotrexate; Opportunistic Infections; Pneumocystis carinii; Pneumon | 2023 |
Combination Immunotherapy with Passive Antibody and Sulfasalazine Accelerates Fungal Clearance and Promotes the Resolution of
Topics: Animals; Anti-Inflammatory Agents; Antibodies; Cytokines; Female; Fungi; Immunologic Factors; Immuno | 2020 |
Effect of sulfasalazine use on the presence of Pneumocystis organisms in the lung among patients with rheumatoid arthritis: A test-negative design case-control study with PCR tests.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Lung; Male; Middle Aged; P | 2019 |
Prophylactic effect of sulfasalazine against Pneumocystis pneumonia in patients with rheumatoid arthritis: A nested case-control study.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Case-Control Studies; Databases, Factual; Female; | 2019 |
Immune modulation with sulfasalazine attenuates immunopathogenesis but enhances macrophage-mediated fungal clearance during Pneumocystis pneumonia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; CD4-Positive T-Lymphocytes; Cell Separation; Enzym | 2010 |
An unusual complication of immunosuppressive therapy in inflammatory bowel disease.
Topics: Aged; Aminosalicylic Acids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antim | 1997 |