sulfasalazine has been researched along with Pheochromocytoma in 4 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
Excerpt | Relevance | Reference |
---|---|---|
"Plasma free metanephrines or urinary fractionated metanephrines are the biochemical tests of choice for the diagnosis of pheochromocytoma as they have greater sensitivity and specificity than catecholamines for pheochromocytoma detection." | 3.96 | Case report of a phantom pheochromocytoma. ( Costelloe, SJ; Joyce, CM; Melvin, A; O'Halloran, DJ; O'Shea, PM, 2020) |
"Sulfasalazine can cause analytical interference in some assays for urinary normetanephrine and result in spuriously elevated levels, leading to misdiagnosis of phaeochromocytoma." | 1.91 | Sulfasalazine as a cause of false-positive elevation of urinary normetanephrine in patients with adrenal mass and suspected phaeochromocytoma: a diagnostic challenge. ( Balasubramanian, S; Debono, M; Rab, E; Zuling, ET, 2023) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (50.00) | 24.3611 |
2020's | 2 (50.00) | 2.80 |
Authors | Studies |
---|---|
Zuling, ET | 1 |
Debono, M | 1 |
Rab, E | 1 |
Balasubramanian, S | 1 |
Joyce, CM | 1 |
Melvin, A | 1 |
O'Shea, PM | 1 |
Costelloe, SJ | 1 |
O'Halloran, DJ | 1 |
Bouhanick, B | 1 |
Fauvel, J | 1 |
Pont, F | 1 |
Rimareix, F | 1 |
Grunenwald, S | 1 |
Vezzosi, D | 1 |
Bennet, A | 1 |
Caron, P | 1 |
4 other studies available for sulfasalazine and Pheochromocytoma
Article | Year |
---|---|
Sulfasalazine as a cause of false-positive elevation of urinary normetanephrine in patients with adrenal mass and suspected phaeochromocytoma: a diagnostic challenge.
Topics: Adrenal Gland Neoplasms; Humans; Metanephrine; Normetanephrine; Pheochromocytoma; Sulfasalazine | 2023 |
Case report of a phantom pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Chromatography, Liquid; Chromogranin A; False Positive React | 2020 |
Biochemical misdiagnosis of pheochromocytoma in patients treated with sulfasalazine.
Topics: Adrenal Gland Neoplasms; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diagnostic Errors; False Pos | 2010 |
[Falsely increased urinary normetanephrine levels during sulfasalazine treatment].
Topics: Adrenal Gland Neoplasms; Adult; Female; Humans; Normetanephrine; Pheochromocytoma; Sulfasalazine | 2012 |