sulfasalazine has been researched along with Pancytopenia in 7 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We describe a patient with rheumatoid arthritis (RA) treated with methotrexate (MTX), sulfasalazine, and low dose corticosteroids, whose case was seriously complicated by the occurrence of acute febrile pancytopenia." | 7.70 | Pancytopenia secondary to hemophagocytic syndrome in rheumatoid arthritis treated with methotrexate and sulfasalazine. ( Albert, A; Cazenave, JP; Javier, RM; Kuntz, JL; Sibilia, J, 1998) |
| " Events included eight patients with malignancies, two with pancytopenia taking methotrexate, three with septic arthritis, and two with septicaemias." | 3.71 | Monitoring and assessing the safety of disease-modifying antirheumatic drugs: a West Midlands experience. ( Bevan, J; Homer, D; Jobanputra, P; Maggs, F, 2002) |
| " We describe a patient with rheumatoid arthritis (RA) treated with methotrexate (MTX), sulfasalazine, and low dose corticosteroids, whose case was seriously complicated by the occurrence of acute febrile pancytopenia." | 3.70 | Pancytopenia secondary to hemophagocytic syndrome in rheumatoid arthritis treated with methotrexate and sulfasalazine. ( Albert, A; Cazenave, JP; Javier, RM; Kuntz, JL; Sibilia, J, 1998) |
| " The syndrome appears to be associated with high dosage and slow acetylator status." | 1.27 | Sulphasalazine associated pancytopenia may be caused by acute folate deficiency. ( Logan, EC; Ryrie, DR; Williamson, LM, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jobanputra, P | 1 |
| Maggs, F | 1 |
| Homer, D | 1 |
| Bevan, J | 1 |
| KOSKINEN, P | 1 |
| Danielson, DA | 1 |
| Douglas, SW | 1 |
| Herzog, P | 1 |
| Jick, H | 1 |
| Porter, JB | 1 |
| Sibilia, J | 1 |
| Javier, RM | 1 |
| Albert, A | 1 |
| Cazenave, JP | 1 |
| Kuntz, JL | 1 |
| Youssef, PP | 1 |
| Bertouch, JV | 1 |
| Logan, EC | 1 |
| Williamson, LM | 1 |
| Ryrie, DR | 1 |
| Prouse, PJ | 1 |
| Shawe, D | 1 |
| Gumpel, JM | 1 |
7 other studies available for sulfasalazine and Pancytopenia
| Article | Year |
|---|---|
Monitoring and assessing the safety of disease-modifying antirheumatic drugs: a West Midlands experience.
Topics: Antirheumatic Agents; Arthritis, Infectious; Azathioprine; Drug Monitoring; Humans; Hypokalemia; Lun | 2002 |
Pancytopenia during salazopyrin treatment; a case report.
Topics: Anemia; Anemia, Aplastic; Humans; Pancytopenia; Sulfanilamide; Sulfanilamides; Sulfasalazine; Sulfon | 1954 |
Drug-induced blood disorders.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Anemia, Hemolytic; Child; Female; Hematologic Diseases; Hu | 1984 |
Pancytopenia secondary to hemophagocytic syndrome in rheumatoid arthritis treated with methotrexate and sulfasalazine.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bacteremia; Bone Marrow Cells; Escherichia coli Infecti | 1998 |
Sulphasalazine induced aplastic anaemia.
Topics: Anemia, Aplastic; Escherichia coli Infections; Female; Humans; Middle Aged; Pancytopenia; Sepsis; Su | 1992 |
Sulphasalazine associated pancytopenia may be caused by acute folate deficiency.
Topics: Adolescent; Adult; Bone Marrow; Female; Folic Acid; Folic Acid Deficiency; Humans; Leucovorin; Male; | 1986 |
Macrocytic anaemia in patients treated with sulphasalazine for rheumatoid arthritis.
Topics: Adult; Aged; Anemia, Macrocytic; Arthritis, Rheumatoid; Female; Folic Acid Deficiency; Humans; Male; | 1986 |