sulfasalazine has been researched along with Nervous System Disorders in 3 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In both instances there was an interval of three weeks between receiving the drug for the first time and the onset of the toxic reaction." | 1.26 | Combined hepatotoxicity and neurotoxicity following sulphasalazine administration. ( Gibson, GE; Rowland, R; Smith, MD, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, MD | 1 |
| Gibson, GE | 1 |
| Rowland, R | 1 |
| Engel, WK | 1 |
| Dorman, JD | 1 |
| Levy, RI | 1 |
| Fredrickson, DS | 1 |
| Wallace, IW | 1 |
3 other studies available for sulfasalazine and Nervous System Disorders
| Article | Year |
|---|---|
Combined hepatotoxicity and neurotoxicity following sulphasalazine administration.
Topics: Adult; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Diseases; Liver | 1982 |
Neuropathy in Tangier disease. Alpha-Lipoprotein deficiency manifesting as familial recurrent neuropathy and intestinal lipid storage.
Topics: Adolescent; Adult; Blood Chemical Analysis; Bone Marrow; Bone Marrow Cells; Cholesterol; Chromatogra | 1967 |
Neurotoxicity associated with a reaction to sulphasalazine.
Topics: Bilirubin; Colitis, Ulcerative; Humans; Liver Function Tests; Male; Middle Aged; Nervous System Dise | 1970 |