sulfasalazine has been researched along with Nerve Degeneration in 2 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malignant brain tumors are characterized by destructive growth and neuronal cell death making them one of the most devastating diseases." | 1.42 | Neurodegeneration and the Brain Tumor Microenvironment. [corrected]. ( Broggini, T; Buchfelder, M; Eyüpoglu, IY; Fan, Z; Savaskan, NE, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Savaskan, NE | 1 |
| Fan, Z | 1 |
| Broggini, T | 1 |
| Buchfelder, M | 1 |
| Eyüpoglu, IY | 1 |
| Brück, W | 1 |
| Brück, Y | 1 |
| Friede, RL | 1 |
2 other studies available for sulfasalazine and Nerve Degeneration
| Article | Year |
|---|---|
Neurodegeneration and the Brain Tumor Microenvironment. [corrected].
Topics: Amino Acid Transport Systems; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Neoplasms; Glu | 2015 |
TNF-alpha suppresses CR3-mediated myelin removal by macrophages.
Topics: Animals; Cytological Techniques; Fluorescent Antibody Technique; Macrophage-1 Antigen; Macrophages; | 1992 |