sulfasalazine has been researched along with Nephritis, Interstitial in 8 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Nephritis, Interstitial: Inflammation of the interstitial tissue of the kidney. This term is generally used for primary inflammation of KIDNEY TUBULES and/or surrounding interstitium. For primary inflammation of glomerular interstitium, see GLOMERULONEPHRITIS. Infiltration of the inflammatory cells into the interstitial compartment results in EDEMA, increased spaces between the tubules, and tubular renal dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to test whether sulfasalazine has a protective action against interstitial inflammation and the development of renal fibrosis in obstructive nephropathy." | 7.74 | Sulfasalazine reduces inflammatory renal injury in unilateral ureteral obstruction. ( Akin, M; Aksoy, RT; Ay, S; Aydin, EN; Demirbilek, S; Edali, MN; Emre, MH; Gürünlüoğlu, K; Tas, E; Yilmaz, Z, 2007) |
| "We describe a case of acute interstitial nephritis that presented after 7 months of sulfasalazine therapy." | 3.76 | Reversal of refractory sulfasalazine-related renal failure after treatment with corticosteroids. ( Alivanis, P; Aperis, G; Arvanitis, A; Karvouniaris, N; Lambrianou, F; Paliouras, C; Zervos, A, 2010) |
| "The purpose of this study was to test whether sulfasalazine has a protective action against interstitial inflammation and the development of renal fibrosis in obstructive nephropathy." | 3.74 | Sulfasalazine reduces inflammatory renal injury in unilateral ureteral obstruction. ( Akin, M; Aksoy, RT; Ay, S; Aydin, EN; Demirbilek, S; Edali, MN; Emre, MH; Gürünlüoğlu, K; Tas, E; Yilmaz, Z, 2007) |
| "A kidney biopsy showed acute tubulointerstitial nephritis with an intense lymphocytic infiltrate and tubular necrosis." | 1.35 | A case of sulphasalazine-induced DRESS syndrome with delayed acute interstitial nephritis. ( Augusto, JF; Chennebault, JM; Cousin, M; Croue, A; Sayegh, J; Simon, A; Subra, JF, 2009) |
| "5-aminosalicylates are extensively prescribed for the treatment of ulcerative colitis but have a wide range of described adverse effects." | 1.31 | Sulphasalazine and mesalazine: serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines. ( Langman, MJ; Ransford, RA, 2002) |
| "Ulcerative colitis is an inflammatory bowel disease with chronic diarrhea, rectal bleeding and characteristic histological findings." | 1.31 | Nephronophthisis and ulcerative colitis in siblings: a new association. ( Ala-Mello, S; Kääriäinen, H; Koskimies, O, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (87.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patel, H | 1 |
| Barr, A | 1 |
| Jeejeebhoy, KN | 1 |
| Augusto, JF | 1 |
| Sayegh, J | 1 |
| Simon, A | 1 |
| Croue, A | 1 |
| Chennebault, JM | 1 |
| Cousin, M | 1 |
| Subra, JF | 1 |
| Alivanis, P | 1 |
| Aperis, G | 1 |
| Lambrianou, F | 1 |
| Zervos, A | 1 |
| Paliouras, C | 1 |
| Karvouniaris, N | 1 |
| Arvanitis, A | 1 |
| Ransford, RA | 1 |
| Langman, MJ | 1 |
| Lewis, JD | 1 |
| Avdeev, VG | 1 |
| Fomin, VV | 1 |
| Popova, EN | 1 |
| Iurkevich, LIu | 1 |
| Osipenko, VI | 1 |
| Sokolina, IA | 1 |
| Popova, IA | 1 |
| Demirbilek, S | 1 |
| Emre, MH | 1 |
| Aydin, EN | 1 |
| Edali, MN | 1 |
| Aksoy, RT | 1 |
| Akin, M | 1 |
| Gürünlüoğlu, K | 1 |
| Tas, E | 1 |
| Ay, S | 1 |
| Yilmaz, Z | 1 |
| Ala-Mello, S | 1 |
| Kääriäinen, H | 1 |
| Koskimies, O | 1 |
1 review available for sulfasalazine and Nephritis, Interstitial
| Article | Year |
|---|---|
[Tubular-interstitial nephritis and fibrosing alveolitis induced by sulfasalazine in ulcerative colitis].
Topics: Colitis, Ulcerative; Gastrointestinal Agents; Humans; Nephritis, Interstitial; Pulmonary Fibrosis; S | 2006 |
7 other studies available for sulfasalazine and Nephritis, Interstitial
| Article | Year |
|---|---|
Renal effects of long-term treatment with 5-aminosalicylic acid.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcera | 2009 |
A case of sulphasalazine-induced DRESS syndrome with delayed acute interstitial nephritis.
Topics: Acute Disease; Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Eruption | 2009 |
Reversal of refractory sulfasalazine-related renal failure after treatment with corticosteroids.
Topics: Acute Disease; Colitis, Ulcerative; Gastrointestinal Agents; Glucocorticoids; Humans; Male; Methylpr | 2010 |
Sulphasalazine and mesalazine: serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Inju | 2002 |
How safe are the safest IBD drugs?
Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal A | 2003 |
Sulfasalazine reduces inflammatory renal injury in unilateral ureteral obstruction.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalase; Female; Fibrosis; Free Radical Scavenger | 2007 |
Nephronophthisis and ulcerative colitis in siblings: a new association.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Chronic Dise | 2001 |