sulfasalazine has been researched along with Neoplasm Metastasis in 3 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, the role of xCT in tumor metastasis remains largely unknown." | 1.35 | Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/beta-catenin pathway. ( Chen, RS; Dong, LJ; Fu, M; Guo, XL; He, X; Li, W; Li, Y; Qiao, HX; Song, YM; Tong, T; Zhan, QM; Zhou, ZY, 2009) |
| "Esophageal cancer is the eighth most common malignancy, and one of the leading causes of cancer-related deaths worldwide." | 1.35 | Targeting NF-kappaB signaling pathway suppresses tumor growth, angiogenesis, and metastasis of human esophageal cancer. ( Cheung, AL; Li, B; Li, YY; Tsao, SW, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ogihara, K | 1 |
| Kikuchi, E | 1 |
| Okazaki, S | 1 |
| Hagiwara, M | 1 |
| Takeda, T | 1 |
| Matsumoto, K | 1 |
| Kosaka, T | 1 |
| Mikami, S | 1 |
| Saya, H | 1 |
| Oya, M | 1 |
| Chen, RS | 1 |
| Song, YM | 1 |
| Zhou, ZY | 1 |
| Tong, T | 1 |
| Li, Y | 1 |
| Fu, M | 1 |
| Guo, XL | 1 |
| Dong, LJ | 1 |
| He, X | 1 |
| Qiao, HX | 1 |
| Zhan, QM | 1 |
| Li, W | 1 |
| Li, B | 1 |
| Li, YY | 1 |
| Tsao, SW | 1 |
| Cheung, AL | 1 |
3 other studies available for sulfasalazine and Neoplasm Metastasis
| Article | Year |
|---|---|
Sulfasalazine could modulate the CD44v9-xCT system and enhance cisplatin-induced cytotoxic effects in metastatic bladder cancer.
Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation | 2019 |
Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/beta-catenin pathway.
Topics: Amino Acid Transport System y+; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Cave | 2009 |
Targeting NF-kappaB signaling pathway suppresses tumor growth, angiogenesis, and metastasis of human esophageal cancer.
Topics: Animals; Esophageal Neoplasms; Female; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice | 2009 |