Page last updated: 2024-11-04

sulfasalazine and Necrosis

sulfasalazine has been researched along with Necrosis in 9 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"We report the simultaneous development of fulminant hepatic failure and necrotizing pancreatitis in a patient treated with sulfasalazine."7.69Sulfasalazine-induced fulminant hepatic failure and necrotizing pancreatitis. ( Rubin, R, 1994)
"We report the simultaneous development of fulminant hepatic failure and necrotizing pancreatitis in a patient treated with sulfasalazine."3.69Sulfasalazine-induced fulminant hepatic failure and necrotizing pancreatitis. ( Rubin, R, 1994)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's2 (22.22)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KEHOE, EL1
NEWCOMER, KL1
Van de Pette, JE1
Cunnah, DT1
Shallcross, TM1
Jullien, D1
Wolkenstein, P1
Roupie, E1
Roujeau, JC1
Revuz, J1
Rubin, R1
Lau, G1
Kwan, C1
Chong, SM1
Ribe, J1
Benkov, KJ1
Thung, SN1
Shen, SC1
LeLeiko, NS1
Haines, JD1
Krakamp, B1
Beinhoff, U1
Knöpfle, G1
Leidig, P1
Wackers, FJ1
Tytgat, GN1
Vreeken, J1

Other Studies

9 other studies available for sulfasalazine and Necrosis

ArticleYear
THROMBOEMBOLIC PHENOMENA IN ULCERATIVE COLITIS. TWO CASE REPORTS.
    Archives of internal medicine, 1964, Volume: 113

    Topics: Anemia; Anemia, Hemolytic; Autoimmune Diseases; Blood Coagulation; Chlordiazepoxide; Colitis; Coliti

1964
Bone marrow necrosis after treatment with sulphasalazine.
    British medical journal (Clinical research ed.), 1984, Sep-29, Volume: 289, Issue:6448

    Topics: Adult; Bone Marrow; Humans; Male; Necrosis; Proctitis; Sulfasalazine

1984
Toxic epidermal necrolysis after sulfasalazine treatment of mild psoriatic arthritis: warning on the use of sulfasalazine for a new indication.
    Arthritis and rheumatism, 1995, Volume: 38, Issue:4

    Topics: Adult; Arthritis, Psoriatic; Epidermis; Female; Humans; Male; Middle Aged; Necrosis; Skin Diseases;

1995
Sulfasalazine-induced fulminant hepatic failure and necrotizing pancreatitis.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:5

    Topics: Adult; Colitis, Ulcerative; Drug Hypersensitivity; Hepatic Encephalopathy; Humans; Male; Necrosis; P

1994
The 3-week sulphasalazine syndrome strikes again.
    Forensic science international, 2001, Nov-01, Volume: 122, Issue:2-3

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Fatal Outcome; Female; Hepatitis; Humans; Myocar

2001
Fatal massive hepatic necrosis: a probable hypersensitivity reaction to sulfasalazine.
    The American journal of gastroenterology, 1986, Volume: 81, Issue:3

    Topics: Adolescent; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Drug Hypersensitivity; Huma

1986
Hepatotoxicity after treatment with sulfasalazine.
    Postgraduate medicine, 1986, May-01, Volume: 79, Issue:6

    Topics: Adult; Chemical and Drug Induced Liver Injury; Crohn Disease; Drug Eruptions; Drug Hypersensitivity;

1986
[Surface necroses of the skin following sulfasalazine therapy in ulcerative colitis].
    Medizinische Klinik (Munich, Germany : 1983), 1988, Sep-16, Volume: 83, Issue:18

    Topics: Adolescent; Colitis, Ulcerative; Humans; Male; Necrosis; Skin; Skin Diseases, Vesiculobullous; Sulfa

1988
Necrotizing vasculitis and ulcerative colitis.
    British medical journal, 1974, Oct-12, Volume: 4, Issue:5936

    Topics: Adult; Ampicillin; Arthritis; Colitis, Ulcerative; Coumarins; Diarrhea; Edema; Elbow; Heparin; Human

1974
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