sulfasalazine has been researched along with Myocarditis in 7 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Myocarditis: Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A young woman thought to have seronegative rheumatoid arthritis developed Stevens-Johnson syndrome after treatment with sulfasalazine; this resolved with prednisone." | 3.79 | Giant cell myocarditis in a patient with a spondyloarthropathy after a drug hypersensitivity reaction. ( Cooper, LT; Davies, RA; Grenon, J; Mesana, TG; Mielniczuk, LM; Mitoff, PR; Veinot, JP, 2013) |
| " Pericarditis as a side effect induced by sulfasalazine or 5-aminosalicylic acid, drugs used in the therapy of these diseases, was first described only 7 years ago." | 2.39 | [Pericarditis in chronic inflammatory bowel disease: underlying disease or side effects of therapy? Clinical problem solving]. ( Krähenbühl, S; Kupferschmidt, H; Langenegger, T, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mitoff, PR | 1 |
| Mesana, TG | 1 |
| Mielniczuk, LM | 1 |
| Grenon, J | 1 |
| Veinot, JP | 1 |
| Cooper, LT | 1 |
| Davies, RA | 1 |
| Mączyński, M | 1 |
| Janus, M | 1 |
| Mularek-Kubzdela, T | 1 |
| Grajek, S | 1 |
| Jeremic, I | 1 |
| Vujasinovic-Stupar, N | 1 |
| Terzic, T | 1 |
| Damjanov, N | 1 |
| Nikolic, M | 1 |
| Bonaci-Nikolic, B | 1 |
| Descamps, V | 1 |
| Kupferschmidt, H | 1 |
| Langenegger, T | 1 |
| Krähenbühl, S | 1 |
| Iizuka, B | 1 |
| Yamagishi, N | 1 |
| Honma, N | 1 |
| Hayashi, N | 1 |
| Lau, G | 1 |
| Kwan, C | 1 |
| Chong, SM | 1 |
2 reviews available for sulfasalazine and Myocarditis
| Article | Year |
|---|---|
[Pericarditis in chronic inflammatory bowel disease: underlying disease or side effects of therapy? Clinical problem solving].
Topics: Adult; Crohn Disease; Drug Combinations; Female; Glucosamine; Humans; Male; Myocarditis; Pericardial | 1996 |
[Cardio vascular disease associated with ulcerative colitis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Female; HLA-B Antigens; HLA-B52 Antige | 1999 |
5 other studies available for sulfasalazine and Myocarditis
| Article | Year |
|---|---|
Giant cell myocarditis in a patient with a spondyloarthropathy after a drug hypersensitivity reaction.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Drug Hypersensitivity; Echocardiography; | 2013 |
Myocarditis and pericarditis in the course of colitis ulcerosa.
Topics: Adult; Colitis; Electrocardiography; Humans; Male; Myocarditis; Pericarditis; Ramipril; Sulfasalazin | 2014 |
Fatal sulfasalazine-induced eosinophilic myocarditis in a patient with periodic fever syndrome.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Autopsy; Eosinophilia; Fatal Outcome; Fev | 2015 |
Drug reaction with eosinophilia and systemic symptoms: a cause of human herpesvirus 6-related fulminant myocarditis and hepatitis in immunocompetent patients.
Topics: Adult; Anti-Infective Agents; Drug-Related Side Effects and Adverse Reactions; Eosinophilia; Female; | 2009 |
The 3-week sulphasalazine syndrome strikes again.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Fatal Outcome; Female; Hepatitis; Humans; Myocar | 2001 |