sulfasalazine has been researched along with Muscle Contraction in 10 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fibrosis/contracture is associated with the abnormal persistence of myofibroblasts, which over-produce and contract collagen matrices." | 5.56 | Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis. ( Atluri, K; Brouillette, MJ; Fowler, TP; Fredericks, D; Khorsand, B; Martin, JA; Petersen, E; Salem, AK; Sander, E; Seol, D; Smith, S, 2020) |
| "Fibrosis/contracture is associated with the abnormal persistence of myofibroblasts, which over-produce and contract collagen matrices." | 1.56 | Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis. ( Atluri, K; Brouillette, MJ; Fowler, TP; Fredericks, D; Khorsand, B; Martin, JA; Petersen, E; Salem, AK; Sander, E; Seol, D; Smith, S, 2020) |
| "The property of anti-ulcerative colitis (anti-UC) was assessed at the levels of both in vitro and in vivo, with X-box-binding protein 1 (XBP1) being targeted in vitro." | 1.48 | Syntheses and structure-activity relationships on antibacterial and anti-ulcerative colitis properties of quaternary 13-substituted palmatines and 8-oxo-13-substituted dihydropalmatines. ( Deng, AJ; Li, J; Li, X; Li, ZH; Qin, HL; Song, L; Wang, SQ; Wu, LQ; Zhang, HJ; Zhang, ZH, 2018) |
| "Cachexia is a relevant comorbid condition of chronic diseases including cancer." | 1.40 | Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness. ( Barreiro, E; Chacon-Cabrera, A; de Kier Joffé, ED; Diament, MJ; Fermoselle, C; Mateu-Jimenez, M; Sandri, M; Urtreger, AJ, 2014) |
| "Using the improved Kirsner model of ulcerative colitis in rabbits, we found that the therapeutic effect of methyl 5-amino salicylate hydrochloride (M-5-AS) was similar to that of sulfasalazine (salicylazosulfapyridine, SZ)." | 1.28 | [Therapeutic effect of methyl 5-aminosalicylate on experimental ulcerative colitis in rabbits]. ( Chen, SY; Chen, ZH; Huang, YF; Liao, YZ; Zhu, KQ; Zhuo, GZ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, ZH | 2 |
| Zhang, HJ | 2 |
| Deng, AJ | 2 |
| Wang, B | 1 |
| Li, ZH | 2 |
| Liu, Y | 1 |
| Wu, LQ | 2 |
| Wang, WJ | 1 |
| Qin, HL | 2 |
| Song, L | 1 |
| Li, J | 1 |
| Li, X | 1 |
| Wang, SQ | 1 |
| Atluri, K | 1 |
| Brouillette, MJ | 1 |
| Seol, D | 1 |
| Khorsand, B | 1 |
| Sander, E | 1 |
| Salem, AK | 1 |
| Fredericks, D | 1 |
| Petersen, E | 1 |
| Smith, S | 1 |
| Fowler, TP | 1 |
| Martin, JA | 1 |
| Chacon-Cabrera, A | 1 |
| Fermoselle, C | 1 |
| Urtreger, AJ | 1 |
| Mateu-Jimenez, M | 1 |
| Diament, MJ | 1 |
| de Kier Joffé, ED | 1 |
| Sandri, M | 1 |
| Barreiro, E | 1 |
| Carlson, CG | 1 |
| Stein, L | 1 |
| Dole, E | 1 |
| Potter, RM | 1 |
| Bayless, D | 1 |
| Hernández, LV | 1 |
| Gonzalo, S | 1 |
| Castro, M | 1 |
| Arruebo, MP | 1 |
| Plaza, MA | 1 |
| Murillo, MD | 1 |
| Grasa, L | 1 |
| Amstutz, I | 1 |
| Diener, M | 1 |
| Liao, YZ | 1 |
| Chen, ZH | 1 |
| Chen, SY | 1 |
| Huang, YF | 1 |
| Zhu, KQ | 1 |
| Zhuo, GZ | 1 |
| Nielsen, ST | 1 |
| Beninati, L | 1 |
| Buonato, CB | 1 |
| Fairburn, RA | 1 |
10 other studies available for sulfasalazine and Muscle Contraction
| Article | Year |
|---|---|
Synthesis and Structure-Activity Relationships of Quaternary Coptisine Derivatives as Potential Anti-ulcerative Colitis Agents.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Berberine; Cell Line; Colitis, Ulcerative; Colon; | 2015 |
Syntheses and structure-activity relationships on antibacterial and anti-ulcerative colitis properties of quaternary 13-substituted palmatines and 8-oxo-13-substituted dihydropalmatines.
Topics: Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Berberine Alkaloids; Body Weight; Candida albican | 2018 |
Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis.
Topics: Aminopropionitrile; Animals; Collagen; Contracture; Disease Models, Animal; Fibrosis; Hydroxyproline | 2020 |
Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness.
Topics: Animals; Autophagy; Boronic Acids; Bortezomib; Butadienes; Cachexia; Cell Line, Tumor; Inflammation; | 2014 |
Agents Which Inhibit NF-κB Signaling Block Spontaneous Contractile Activity and Negatively Influence Survival of Developing Myotubes.
Topics: Animals; Apoptosis; Cell Differentiation; Cell Survival; Cells, Cultured; Fluorescent Antibody Techn | 2016 |
Nuclear factor κB is a key transcription factor in the duodenal contractility alterations induced by lipopolysaccharide.
Topics: Animals; Cytokines; Duodenum; Gastrointestinal Motility; Lipopolysaccharides; Male; Muscle Contracti | 2011 |
Inhibition of antigen-induced muscle contractions by inhibitors of thromboxane pathway in rat small intestine.
Topics: Animals; Antigens; Atropine; Benzimidazoles; Benzoxepins; Carbachol; Cyclooxygenase Inhibitors; Dose | 1997 |
[Therapeutic effect of methyl 5-aminosalicylate on experimental ulcerative colitis in rabbits].
Topics: Aminosalicylic Acids; Animals; Colitis, Ulcerative; Colon; Gastric Fundus; In Vitro Techniques; Musc | 1990 |
Sulfasalazine and 5-aminosalicylic acid inhibit contractile leukotriene formation.
Topics: Aminosalicylic Acids; Animals; Calcimycin; Cell Separation; Mesalamine; Muscle Contraction; Muscle, | 1988 |
On the aetiology of ulcerative colitis. A vascular hypothesis.
Topics: Adult; Age Factors; Animals; Child; Colitis, Ulcerative; Diarrhea; Dogs; Female; Gastrointestinal Mo | 1973 |