sulfasalazine has been researched along with Megacolon, Toxic in 5 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Megacolon, Toxic: An acute form of MEGACOLON, severe pathological dilatation of the COLON. It is associated with clinical conditions such as ULCERATIVE COLITIS; CROHN DISEASE; AMEBIC DYSENTERY; or CLOSTRIDIUM ENTEROCOLITIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Medical treatment, including increased dosage of steroids, failed to control UC and acute thrombocytopenia in this patient." | 1.33 | Acute thrombocytopenia associated with preexisting ulcerative colitis successfully treated with colectomy. ( Hisada, T; Iida, T; Ishizuka, T; Kusano, M; Masuo, T; Miyamae, Y; Mizuide, M; Mori, M; Okada, S; Sagawa, T; Shibusawa, N, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hisada, T | 1 |
| Miyamae, Y | 1 |
| Mizuide, M | 1 |
| Shibusawa, N | 1 |
| Iida, T | 1 |
| Masuo, T | 1 |
| Okada, S | 1 |
| Sagawa, T | 1 |
| Ishizuka, T | 1 |
| Kusano, M | 1 |
| Mori, M | 1 |
| Bárány, F | 1 |
| Krause, U | 1 |
| Larizza, D | 1 |
| Boni, R | 1 |
| Tsuchiya, M | 1 |
| Kobayashi, K | 1 |
| Aiso, S | 1 |
| Watanabe, M | 1 |
| Yoshida, T | 1 |
| Ishikawa, M | 1 |
| Yoshioka, M | 1 |
| Hamada, Y | 1 |
| Asakura, H | 1 |
| Ando, K | 1 |
| Bamba, T | 1 |
| Nishiyama, Y | 1 |
2 reviews available for sulfasalazine and Megacolon, Toxic
| Article | Year |
|---|---|
[Ulcerative rectocolitis: current clinical and therapeutic concepts].
Topics: Adrenal Cortex Hormones; Colectomy; Colitis, Ulcerative; Colonic Neoplasms; Colposcopy; Crohn Diseas | 1982 |
[Clinical features and management of the elderly patients with ulcerative colitis].
Topics: Age of Onset; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; | 1999 |
3 other studies available for sulfasalazine and Megacolon, Toxic
| Article | Year |
|---|---|
Acute thrombocytopenia associated with preexisting ulcerative colitis successfully treated with colectomy.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents; Colectomy; Colitis, Ulcerative; Glucocorticoids; Hum | 2006 |
[Management of patients with fulminating colitis].
Topics: Adrenal Cortex Hormones; Colectomy; Colitis, Ulcerative; Humans; Megacolon, Toxic; Sulfasalazine | 1980 |
[Clinical features and management of 7 cases of toxic megacolon].
Topics: Adolescent; Adult; Colitis, Ulcerative; Female; Humans; Male; Megacolon, Toxic; Prednisolone; Sulfas | 1983 |