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sulfasalazine and MS (Multiple Sclerosis)

sulfasalazine has been researched along with MS (Multiple Sclerosis) in 7 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Research Excerpts

ExcerptRelevanceReference
"Sulfasalazine is an anti-inflammatory and immune-modulating drug that is used in rheumatology and inflammatory bowel disease."1.42Promotion of Remyelination by Sulfasalazine in a Transgenic Zebrafish Model of Demyelination. ( Chang, KY; Cho, SC; Ha, YW; Kim, S; Lee, DW; Lee, YI; Na, JE; Park, HC; Park, SC; Rhyu, IJ, 2015)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's5 (71.43)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, S1
Lee, YI1
Chang, KY1
Lee, DW1
Cho, SC1
Ha, YW1
Na, JE1
Rhyu, IJ1
Park, SC1
Park, HC1
Noseworthy, JH1
O'Brien, P1
Erickson, BJ1
Lee, D1
Sneve, D1
Ebers, GC1
Rice, GP1
Auty, A1
Hader, WJ1
Kirk, A1
Duquette, P1
Carter, J1
Francis, G1
Metz, L1
Shuster, E1
Rudge, P1
Paty, DW1
Uitdehaag, BM1
Polman, CH1
de Groot, CJ1
Huitinga, I1
Dijkstra, CD1
Gold, R1
Kappos, L1
Becker, T1
Prosiegel, M1
Neu, I1
Ruhenstroth-Bauer, G1
Hoffmann, G1
Vogl, S1
Mehlber, L1
Wildfeuer, A1

Trials

1 trial available for sulfasalazine and MS (Multiple Sclerosis)

ArticleYear
The Mayo Clinic-Canadian Cooperative trial of sulfasalazine in active multiple sclerosis.
    Neurology, 1998, Volume: 51, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Brain; Canada; Disabled Persons; Disease Progression

1998

Other Studies

6 other studies available for sulfasalazine and MS (Multiple Sclerosis)

ArticleYear
Promotion of Remyelination by Sulfasalazine in a Transgenic Zebrafish Model of Demyelination.
    Molecules and cells, 2015, Volume: 38, Issue:11

    Topics: Animals; Animals, Genetically Modified; Anti-Inflammatory Agents, Non-Steroidal; Axons; Disease Mode

2015
Are clinical trials of therapeutic agents for MS long enough?
    Lancet (London, England), 1999, Mar-27, Volume: 353, Issue:9158

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Humans; Interferon-beta; Multiple

1999
The Mayo Clinic-Canadian cooperative trial of sulfasalazine in active multiple sclerosis.
    Neurology, 1999, Jul-22, Volume: 53, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Canada; Clinical Trials as Topic; Humans; Minnesota; Multip

1999
Failure of sulfasalazine to influence experimental autoimmune encephalomyelitis.
    Acta neurologica Scandinavica, 1991, Volume: 84, Issue:2

    Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Humans; Multiple Sclerosis; Neurologic Examina

1991
Development of multiple sclerosis in patient on long-term sulfasalazine.
    Lancet (London, England), 1990, Feb-17, Volume: 335, Issue:8686

    Topics: Adult; Colitis, Ulcerative; Drug Administration Schedule; Humans; Male; Multiple Sclerosis; Sulfasal

1990
Suppression of experimental autoimmune encephalomyelitis by sulfasalazine.
    The New England journal of medicine, 1989, 08-24, Volume: 321, Issue:8

    Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Multiple Sclerosis; Sulfa

1989