sulfasalazine has been researched along with Lymphoma, Large B-Cell, Diffuse in 2 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Lymphoma, Large B-Cell, Diffuse: Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulfasalazine (SFZ) is a synthetic anti-inflammatory comprising an aminosalicylate, 5-amino salicylic acid (5-ASA), linked to an antibiotic, sulfapyridine (SPY)." | 1.33 | Novel sulfasalazine analogues with enhanced NF-kB inhibitory and apoptosis promoting activity. ( Ganesan, A; Habens, F; Mann, DA; Oakley, F; Packham, G; Srinivasan, N, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshinaga, N | 1 |
| Oka, S | 1 |
| Asagoe, K | 1 |
| Habens, F | 1 |
| Srinivasan, N | 1 |
| Oakley, F | 1 |
| Mann, DA | 1 |
| Ganesan, A | 1 |
| Packham, G | 1 |
2 other studies available for sulfasalazine and Lymphoma, Large B-Cell, Diffuse
| Article | Year |
|---|---|
[Regression of diffuse large B-cell lymphoma after discontinuation of salazosulfapyridine].
Topics: Arthritis, Rheumatoid; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoproliferative Disorders; Male; | 2022 |
Novel sulfasalazine analogues with enhanced NF-kB inhibitory and apoptosis promoting activity.
Topics: Animals; Apoptosis; B-Lymphocytes; Cell Line; Cell Line, Tumor; Cell Transformation, Viral; Herpesvi | 2005 |