sulfasalazine has been researched along with Lupus Erythematosus, Discoid in 7 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Lupus Erythematosus, Discoid: A chronic form of cutaneous lupus erythematosus (LUPUS ERYTHEMATOSUS, CUTANEOUS) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulfasalazine is an effective agent for chronic discoid lupus erythematosus (CDLE) but the response to treatment is considerably variable between patients and is also unpredictable." | 1.30 | NAT2 genotyping and efficacy of sulfasalazine in patients with chronic discoid lupus erythematosus. ( Broly, F; Delaporte, E; Lo-Guidice, JM; Marez, D; Piette, F; Sabbagh, N, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Francès, C | 2 |
| Barete, S | 1 |
| Ayoub, N | 1 |
| Piette, JC | 2 |
| Delaporte, E | 3 |
| Piette, F | 3 |
| Bourjot, D | 1 |
| Duneton-Bitbol, V | 1 |
| Bergoend, H | 2 |
| Papo, T | 1 |
| Godeau, P | 1 |
| Artüz, F | 1 |
| Lenk, N | 1 |
| Deniz, N | 1 |
| Alli, N | 1 |
| Sabbagh, N | 2 |
| Marez, D | 1 |
| Lo-Guidice, JM | 1 |
| Broly, F | 2 |
| Catteau, B | 1 |
| Gosselin, P | 1 |
| Breuillard, F | 1 |
| Doutre, MS | 1 |
| Carmichael, AJ | 1 |
| Paul, CJ | 1 |
1 trial available for sulfasalazine and Lupus Erythematosus, Discoid
| Article | Year |
|---|---|
Efficacy of sulfasalazine in discoid lupus erythematosus.
Topics: Adult; Anti-Inflammatory Agents; Arachidonic Acids; Female; Humans; Lupus Erythematosus, Discoid; Ma | 1996 |
6 other studies available for sulfasalazine and Lupus Erythematosus, Discoid
| Article | Year |
|---|---|
[Classification of dermatologic manifestations in lupus erythematosus].
Topics: Acitretin; Adrenal Cortex Hormones; Adult; Antimalarials; Clinical Trials as Topic; Dapsone; Dermato | 2003 |
[Treatment of chronic lupus erythematosus with sulfasalazine].
Topics: Adult; Female; Humans; Lupus Erythematosus, Discoid; Male; Middle Aged; Sulfasalazine | 1994 |
[Sulfasalazine or interferon in the treatment of lupus: the hen, the egg and the wolf].
Topics: Antibodies, Antinuclear; Humans; Interferon-alpha; Lupus Erythematosus, Discoid; Lupus Erythematosus | 1994 |
NAT2 genotyping and efficacy of sulfasalazine in patients with chronic discoid lupus erythematosus.
Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Female; Genotype; Humans; Lupus Erythematosus, Di | 1997 |
[Treatment of discoid lupus erythematosus with sulfasalazine: 11 cases].
Topics: Acetylation; Acetyltransferases; Adult; Anti-Inflammatory Agents; Antibodies, Antinuclear; Facial De | 1997 |
Discoid lupus erythematosus responsive to sulphasalazine.
Topics: Female; Humans; Lupus Erythematosus, Discoid; Middle Aged; Sulfasalazine | 1991 |