sulfasalazine has been researched along with Liver Failure, Acute in 2 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We describe a 60-year-old man with polyarthritis treated with sulfasalazine who developed DRESS and fulminant liver failure after additional vancomycin treatment." | 7.75 | Fulminant liver failure after vancomycin in a sulfasalazine-induced DRESS syndrome: fatal recurrence after liver transplantation. ( Candinas, D; Inderbitzin, D; Keller, M; Keogh, A; Mennicke, M; Pichler, WJ; Stickel, F; Wilkens, L; Yawalkar, N; Zawodniak, A, 2009) |
| " We describe a 60-year-old man with polyarthritis treated with sulfasalazine who developed DRESS and fulminant liver failure after additional vancomycin treatment." | 3.75 | Fulminant liver failure after vancomycin in a sulfasalazine-induced DRESS syndrome: fatal recurrence after liver transplantation. ( Candinas, D; Inderbitzin, D; Keller, M; Keogh, A; Mennicke, M; Pichler, WJ; Stickel, F; Wilkens, L; Yawalkar, N; Zawodniak, A, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mennicke, M | 1 |
| Zawodniak, A | 1 |
| Keller, M | 1 |
| Wilkens, L | 1 |
| Yawalkar, N | 1 |
| Stickel, F | 1 |
| Keogh, A | 1 |
| Inderbitzin, D | 1 |
| Candinas, D | 1 |
| Pichler, WJ | 1 |
| Descloux, E | 1 |
| Argaud, L | 1 |
| Dumortier, J | 1 |
| Scoazec, JY | 1 |
| Boillot, O | 1 |
| Robert, D | 1 |
2 other studies available for sulfasalazine and Liver Failure, Acute
| Article | Year |
|---|---|
Fulminant liver failure after vancomycin in a sulfasalazine-induced DRESS syndrome: fatal recurrence after liver transplantation.
Topics: Arthritis; Drug Hypersensitivity; Eosinophilia; Fas Ligand Protein; Fatal Outcome; Granzymes; Humans | 2009 |
Favourable issue of a fulminant hepatitis associated with sulfasalazine DRESS syndrome without liver transplantation.
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Drug Eruptio | 2005 |