sulfasalazine has been researched along with Leucocythaemia in 3 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Conceptually, it is accepted that MTX and folic acid are transported by folate receptors (FRs) in cancerous cells, but the exact mechanism of MTX uptake in human leukemia is unknown." | 3.75 | Differential usage of the transport systems for folic acid and methotrexate in normal human T-lymphocytes and leukemic cells. ( Biswal, BK; Verma, RS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biswal, BK | 1 |
| Verma, RS | 1 |
| ROSEN, RB | 1 |
| TEPLITZ, RL | 1 |
| Sykes, AP | 1 |
| Brampton, C | 1 |
| Klee, S | 1 |
| Chander, CL | 1 |
| Whelan, C | 1 |
| Parsons, ME | 1 |
3 other studies available for sulfasalazine and Leucocythaemia
| Article | Year |
|---|---|
Differential usage of the transport systems for folic acid and methotrexate in normal human T-lymphocytes and leukemic cells.
Topics: Antibodies; Biological Transport; Buffers; Carrier Proteins; Cell Line, Tumor; Folate Receptors, GPI | 2009 |
CHRONIC GRANULOCYTIC LEUKEMIA COMPLICATED BY ULCERATIVE COLITIS: ELEVATED LEUKOCYTE ALKALINE PHOSPHATASE AND POSSIBLE MODIFIER GENE DELETION.
Topics: Adolescent; Alkaline Phosphatase; Blood Cell Count; Chromosomes; Colitis, Ulcerative; Diet; Diet The | 1965 |
An investigation into the effect and mechanisms of action of nicotine in inflammatory bowel disease.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammatory Bowel Diseases; Leukemia; Leu | 2000 |