sulfasalazine has been researched along with Ischemia in 3 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present study was to determine whether the split products of sulfasalazine, sulfapyridine, and 5-aminosalicylic acid can ameliorate ischemia/reperfusion-induced injury to the gastric mucosa." | 3.67 | 5-Aminosalicylic acid protects against ischemia/reperfusion-induced gastric bleeding in the rat. ( Grisham, MB; Kvietys, PR; Manci, EA; Smith, SM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ryu, BR | 1 |
| Lee, YA | 1 |
| Won, SJ | 1 |
| Noh, JH | 1 |
| Chang, SY | 1 |
| Chung, JM | 1 |
| Choi, JS | 1 |
| Joo, CK | 1 |
| Yoon, SH | 1 |
| Gwag, BJ | 1 |
| Kvietys, PR | 1 |
| Smith, SM | 1 |
| Grisham, MB | 1 |
| Manci, EA | 1 |
| Arvanitakis, C | 1 |
| Malek, G | 1 |
| Uehling, D | 1 |
| Morrissey, JF | 1 |
3 other studies available for sulfasalazine and Ischemia
| Article | Year |
|---|---|
The novel neuroprotective action of sulfasalazine through blockade of NMDA receptors.
Topics: Animals; Antioxidants; Calcium; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 2; Disease Models, | 2003 |
5-Aminosalicylic acid protects against ischemia/reperfusion-induced gastric bleeding in the rat.
Topics: Aminosalicylic Acids; Animals; Dimethyl Sulfoxide; Gastrointestinal Hemorrhage; Hydroxides; Hydroxyl | 1988 |
Colonic complications after renal transplantation.
Topics: Adolescent; Adult; Azathioprine; Cadaver; Colectomy; Colitis; Colon; Diarrhea; Female; Gastrointesti | 1973 |