sulfasalazine has been researched along with Invasiveness, Neoplasm in 6 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "CD133-positive cells in hepatocellular carcinoma (HCC) exhibit cancer stem cell (CSC)-like properties as well as resistance to chemotherapeutic agents and ionizing radiation; however, their function remains unknown." | 5.46 | Sulfasalazine attenuates evading anticancer response of CD133-positive hepatocellular carcinoma cells. ( Bae, SM; Choi, EK; Jang, J; Kim, JS; Kim, KM; Myung, SJ; Seo, HR; Shin, TH; Song, Y, 2017) |
| "CD133-positive cells in hepatocellular carcinoma (HCC) exhibit cancer stem cell (CSC)-like properties as well as resistance to chemotherapeutic agents and ionizing radiation; however, their function remains unknown." | 1.46 | Sulfasalazine attenuates evading anticancer response of CD133-positive hepatocellular carcinoma cells. ( Bae, SM; Choi, EK; Jang, J; Kim, JS; Kim, KM; Myung, SJ; Seo, HR; Shin, TH; Song, Y, 2017) |
| "However, the role of xCT in tumor metastasis remains largely unknown." | 1.35 | Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/beta-catenin pathway. ( Chen, RS; Dong, LJ; Fu, M; Guo, XL; He, X; Li, W; Li, Y; Qiao, HX; Song, YM; Tong, T; Zhan, QM; Zhou, ZY, 2009) |
| "An increased incidence of colonic cancer is associated with chronic inflammatory bowel disease." | 1.28 | The effect of therapeutic drugs used in inflammatory bowel disease on the incidence and growth of colonic cancer in the dimethylhydrazine rat model. ( Crouch, R; Davis, AE; Patterson, F, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blecic, S | 1 |
| Rynkowski, M | 1 |
| De Witte, O | 1 |
| Lefranc, F | 1 |
| Song, Y | 1 |
| Jang, J | 1 |
| Shin, TH | 1 |
| Bae, SM | 1 |
| Kim, JS | 1 |
| Kim, KM | 1 |
| Myung, SJ | 1 |
| Choi, EK | 1 |
| Seo, HR | 1 |
| Chen, RS | 1 |
| Song, YM | 1 |
| Zhou, ZY | 1 |
| Tong, T | 1 |
| Li, Y | 1 |
| Fu, M | 1 |
| Guo, XL | 1 |
| Dong, LJ | 1 |
| He, X | 1 |
| Qiao, HX | 1 |
| Zhan, QM | 1 |
| Li, W | 1 |
| Lay, JD | 1 |
| Hong, CC | 1 |
| Huang, JS | 1 |
| Yang, YY | 1 |
| Pao, CY | 1 |
| Liu, CH | 1 |
| Lai, YP | 1 |
| Lai, GM | 1 |
| Cheng, AL | 1 |
| Su, IJ | 1 |
| Chuang, SE | 1 |
| Lyons, SA | 1 |
| Chung, WJ | 1 |
| Weaver, AK | 1 |
| Ogunrinu, T | 1 |
| Sontheimer, H | 1 |
| Davis, AE | 1 |
| Patterson, F | 1 |
| Crouch, R | 1 |
1 review available for sulfasalazine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
[Glutamate and malignant gliomas, from epilepsia to biological aggressiveness: therapeutic implications].
Topics: Benzodiazepines; Brain Neoplasms; Cell Death; Cell Movement; Cell Proliferation; Dizocilpine Maleate | 2013 |
5 other studies available for sulfasalazine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Sulfasalazine attenuates evading anticancer response of CD133-positive hepatocellular carcinoma cells.
Topics: AC133 Antigen; Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Cell Line, Tumor; Drug R | 2017 |
Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/beta-catenin pathway.
Topics: Amino Acid Transport System y+; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Cave | 2009 |
Sulfasalazine suppresses drug resistance and invasiveness of lung adenocarcinoma cells expressing AXL.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Axl Receptor Tyrosine Kinase; Cell L | 2007 |
Autocrine glutamate signaling promotes glioma cell invasion.
Topics: Amino Acid Transport System y+; Animals; Brain Neoplasms; Calcium; Cell Line, Tumor; Cell Movement; | 2007 |
The effect of therapeutic drugs used in inflammatory bowel disease on the incidence and growth of colonic cancer in the dimethylhydrazine rat model.
Topics: Adenocarcinoma; Aminosalicylic Acids; Animals; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazin | 1992 |