sulfasalazine has been researched along with Intestinal Diseases in 25 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Intestinal Diseases: Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Etiology and pathogenesis of Crohn's disease, the incidence of which seems to be increasing lately, are still unknown." | 1.26 | [Clinical features of inflammatory bowel disease (author's transl)]. ( Classen, M; Leuschner, U; Strohm, WD, 1982) |
| "Sulfasalazine alone was used in 24 patients, steroids alone were used in four patients, both drugs were used together in 29 patients and azathioprine was added to the drug regimen of five patients." | 1.26 | Anti-inflammatory drug treatment in Crohn's disease. ( Abramson, J; Goldstein, F; Thornton, JJ, 1976) |
| "Sulfasalazine has proven to be an effective agent in the therapy of inflammatory bowel disease (IBD)." | 1.26 | Effects of sulfasalazine on selected lymphocyte subpopulations in vivo and in vitro. ( Charland, C; Field, CE; Thayer, WR, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (76.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pilgrim, S | 1 |
| Velchuru, V | 1 |
| Waters, G | 1 |
| Tsiamis, A | 1 |
| Lal, R | 1 |
| Jung, YS | 1 |
| Cheon, JH | 1 |
| Park, SJ | 1 |
| Hong, SP | 1 |
| Kim, TI | 1 |
| Kim, WH | 1 |
| Kirsner, JB | 1 |
| Hansen, W | 1 |
| Leuschner, U | 1 |
| Strohm, WD | 1 |
| Classen, M | 1 |
| Janowitz, HD | 1 |
| Sachar, DB | 1 |
| Petrelli, EA | 1 |
| McKinley, M | 1 |
| Troncale, FJ | 1 |
| Cosentino, MJ | 1 |
| Chey, WY | 1 |
| Takihara, H | 1 |
| Cockett, AT | 1 |
| Dzierzewicz, Z | 1 |
| Cwalina, B | 1 |
| Gawlik, B | 1 |
| Wilczok, T | 1 |
| Gonciarz, Z | 1 |
| Matsukawa, M | 1 |
| Kouda, T | 1 |
| Hisamatsu, T | 1 |
| Kishikawa, H | 1 |
| Fukuya, H | 1 |
| Matsuoka, K | 1 |
| Mizuno, Y | 1 |
| Nishida, J | 1 |
| Goldstein, F | 1 |
| Thornton, JJ | 1 |
| Abramson, J | 1 |
| Chevrel, B | 1 |
| Thayer, WR | 1 |
| Charland, C | 1 |
| Field, CE | 1 |
| Simenon, G | 1 |
| Van Gossum, A | 1 |
| Adler, M | 1 |
| Rickaert, F | 1 |
| Appelboom, T | 1 |
| Donowitz, M | 1 |
| Del Soldato, P | 1 |
| Foschi, D | 1 |
| Varin, L | 1 |
| Daniotti, S | 1 |
| Mielants, H | 1 |
| Veys, EM | 1 |
| Joos, R | 1 |
| Modigliani, R | 1 |
| Rambaud, JC | 1 |
| Ahnfelt-Rønne, I | 1 |
| Nielsen, OH | 1 |
| Bukhave, K | 1 |
| Elmgreen, J | 1 |
| Gendre, JP | 1 |
| Gall, DG | 1 |
| Hamilton, JR | 1 |
| Demling, L | 1 |
| Archampong, EQ | 1 |
| Harris, J | 1 |
| Clark, CG | 1 |
| Miller, B | 1 |
| Engelhart, A | 1 |
| Goebel, KM | 1 |
| Schmidt, J | 1 |
| Martini, GA | 1 |
7 reviews available for sulfasalazine and Intestinal Diseases
| Article | Year |
|---|---|
Observations on the medical treatment of inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Clinical Trials as Topic; Colitis, Ulcerative; Crohn | 1980 |
[Dietary and drug therapy of intestinal disease].
Topics: Aerophagy; Anti-Inflammatory Agents; Atropine; beta-Galactosidase; Cathartics; Colitis, Ulcerative; | 1980 |
Inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Adult; Child; Colectomy; Colitis, Ulcerative; Crohn Disease; Female; Humans | 1982 |
[Therapy and nutrition for intestinal Behçet disease and simple ulcer].
Topics: Adult; Anhydrides; Behcet Syndrome; Colectomy; Enteral Nutrition; Ethanol; Female; Humans; Intestina | 2001 |
[New salazosulfapyridine derivatives. Progress in the treatment of chronic inflammatory diseases of the intestines?].
Topics: Administration, Oral; Administration, Rectal; Chronic Disease; Colitis, Ulcerative; Crohn Disease; D | 1987 |
[New forms of 5-aminosalicylate in inflammatory intestinal lesions].
Topics: Aminosalicylic Acids; Drug Combinations; Glucosamine; Humans; Inflammation; Intestinal Diseases; Mes | 1987 |
Chronic diarrhea in childhood: a new look at an old problem.
Topics: Celiac Disease; Chlorides; Chronic Disease; Cystic Fibrosis; Diarrhea; Diet Therapy; Food Hypersensi | 1974 |
1 trial available for sulfasalazine and Intestinal Diseases
| Article | Year |
|---|---|
Observations on the medical treatment of inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Clinical Trials as Topic; Colitis, Ulcerative; Crohn | 1980 |
18 other studies available for sulfasalazine and Intestinal Diseases
| Article | Year |
|---|---|
Diaphragm disease and small bowel enteropathy due to nonsteroidal anti-inflammatory drugs: a surgical perspective.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Constriction, Pathologic; Diaphragm; Diclofe | 2011 |
Clinical course of intestinal Behcet's disease during the first five years.
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; Disease Pr | 2013 |
[Clinical features of inflammatory bowel disease (author's transl)].
Topics: Azathioprine; Bacterial Infections; Crohn Disease; Diarrhea; Drug Combinations; Fluid Therapy; Gluco | 1982 |
Ocular manifestations of inflammatory bowel disease.
Topics: Adult; Aged; Corneal Ulcer; Crohn Disease; Eye Diseases; Female; Humans; Hydrocortisone; Inflammatio | 1982 |
The effects of sulfasalazine on human male fertility potential and seminal prostaglandins.
Topics: Adult; Dinoprost; Dinoprostone; Fertility; Follicle Stimulating Hormone; Humans; Inflammation; Intes | 1984 |
Isolation and evaluation of susceptibility to sulphasalazine of Desulfovibrio desulfuricans strains from the human digestive tract.
Topics: Adenoma; Adult; Anti-Bacterial Agents; Bacteriological Techniques; Biopsy; Colon; Colonic Diseases, | 1997 |
Combination therapy including pentoxifylline for entero-Behçet's disease.
Topics: Adult; Aged; Anti-Inflammatory Agents; Behcet Syndrome; Drug Therapy, Combination; Female; Humans; I | 2001 |
Anti-inflammatory drug treatment in Crohn's disease.
Topics: Anti-Inflammatory Agents; Azathioprine; Colonic Diseases; Crohn Disease; Female; Humans; Intestinal | 1976 |
[Inflammatory diseases of the colon and salazopyrine. Value of long term treatment].
Topics: Chemical Phenomena; Chemistry; Colitis; Colonic Diseases; Crohn Disease; Female; Gastrointestinal He | 1976 |
Effects of sulfasalazine on selected lymphocyte subpopulations in vivo and in vitro.
Topics: Antibody-Dependent Cell Cytotoxicity; B-Lymphocytes; Cells, Cultured; Humans; Immunoglobulin G; Immu | 1979 |
Macroscopic and microscopic gut lesions in seronegative spondyloarthropathies.
Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents, Non-Steroidal; Colon; Colonoscopy; Female; Humans; | 1990 |
Arachidonic acid metabolites and their role in inflammatory bowel disease. An update requiring addition of a pathway.
Topics: Aminosalicylic Acids; Arachidonic Acid; Arachidonic Acids; Biological Transport; Bradykinin; Colitis | 1985 |
Indomethacin-induced intestinal ulcers in rats: effects of salicylazosulfapyridine and dexamethasone.
Topics: Animals; Dexamethasone; Female; Indomethacin; Inflammation; Intestinal Diseases; Rats; Sulfasalazine | 1985 |
Sulphasalazine (Salazopyrin) in the treatment of enterogenic reactive synovitis and ankylosing spondylitis with peripheral arthritis.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Arthritis; Bacterial Infections; Drug Evaluation; Drug | 1986 |
Sulfasalazine and its anti-inflammatory metabolite, 5-aminosalicylic acid: effect on arachidonic acid metabolism in human neutrophils, and free radical scavenging.
Topics: Aminosalicylic Acids; Arachidonic Acid; Arachidonic Acids; Biphenyl Compounds; Free Radicals; Humans | 1987 |
[51. Inflammatory diseases of the large intestine. (Internistic report)].
Topics: Adrenal Cortex Hormones; Colitis, Ulcerative; Crohn Disease; Diagnosis, Differential; Humans; Inflam | 1967 |
Water and electrolyte transfer by colonic mucosa studied in vitro.
Topics: Azathioprine; Colon; Humans; In Vitro Techniques; Intestinal Absorption; Intestinal Diseases; Intest | 1972 |
[Methemoglobin synthesis during azulfidine therapy].
Topics: Adult; Colitis, Ulcerative; Female; Humans; Intestinal Diseases; Male; Methemoglobin; Methemoglobine | 1971 |