sulfasalazine has been researched along with Interstitial Nephritis in 8 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to test whether sulfasalazine has a protective action against interstitial inflammation and the development of renal fibrosis in obstructive nephropathy." | 7.74 | Sulfasalazine reduces inflammatory renal injury in unilateral ureteral obstruction. ( Akin, M; Aksoy, RT; Ay, S; Aydin, EN; Demirbilek, S; Edali, MN; Emre, MH; Gürünlüoğlu, K; Tas, E; Yilmaz, Z, 2007) |
| "We describe a case of acute interstitial nephritis that presented after 7 months of sulfasalazine therapy." | 3.76 | Reversal of refractory sulfasalazine-related renal failure after treatment with corticosteroids. ( Alivanis, P; Aperis, G; Arvanitis, A; Karvouniaris, N; Lambrianou, F; Paliouras, C; Zervos, A, 2010) |
| "The purpose of this study was to test whether sulfasalazine has a protective action against interstitial inflammation and the development of renal fibrosis in obstructive nephropathy." | 3.74 | Sulfasalazine reduces inflammatory renal injury in unilateral ureteral obstruction. ( Akin, M; Aksoy, RT; Ay, S; Aydin, EN; Demirbilek, S; Edali, MN; Emre, MH; Gürünlüoğlu, K; Tas, E; Yilmaz, Z, 2007) |
| "A kidney biopsy showed acute tubulointerstitial nephritis with an intense lymphocytic infiltrate and tubular necrosis." | 1.35 | A case of sulphasalazine-induced DRESS syndrome with delayed acute interstitial nephritis. ( Augusto, JF; Chennebault, JM; Cousin, M; Croue, A; Sayegh, J; Simon, A; Subra, JF, 2009) |
| "5-aminosalicylates are extensively prescribed for the treatment of ulcerative colitis but have a wide range of described adverse effects." | 1.31 | Sulphasalazine and mesalazine: serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines. ( Langman, MJ; Ransford, RA, 2002) |
| "Ulcerative colitis is an inflammatory bowel disease with chronic diarrhea, rectal bleeding and characteristic histological findings." | 1.31 | Nephronophthisis and ulcerative colitis in siblings: a new association. ( Ala-Mello, S; Kääriäinen, H; Koskimies, O, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (87.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patel, H | 1 |
| Barr, A | 1 |
| Jeejeebhoy, KN | 1 |
| Augusto, JF | 1 |
| Sayegh, J | 1 |
| Simon, A | 1 |
| Croue, A | 1 |
| Chennebault, JM | 1 |
| Cousin, M | 1 |
| Subra, JF | 1 |
| Alivanis, P | 1 |
| Aperis, G | 1 |
| Lambrianou, F | 1 |
| Zervos, A | 1 |
| Paliouras, C | 1 |
| Karvouniaris, N | 1 |
| Arvanitis, A | 1 |
| Ransford, RA | 1 |
| Langman, MJ | 1 |
| Lewis, JD | 1 |
| Avdeev, VG | 1 |
| Fomin, VV | 1 |
| Popova, EN | 1 |
| Iurkevich, LIu | 1 |
| Osipenko, VI | 1 |
| Sokolina, IA | 1 |
| Popova, IA | 1 |
| Demirbilek, S | 1 |
| Emre, MH | 1 |
| Aydin, EN | 1 |
| Edali, MN | 1 |
| Aksoy, RT | 1 |
| Akin, M | 1 |
| Gürünlüoğlu, K | 1 |
| Tas, E | 1 |
| Ay, S | 1 |
| Yilmaz, Z | 1 |
| Ala-Mello, S | 1 |
| Kääriäinen, H | 1 |
| Koskimies, O | 1 |
1 review available for sulfasalazine and Interstitial Nephritis
| Article | Year |
|---|---|
[Tubular-interstitial nephritis and fibrosing alveolitis induced by sulfasalazine in ulcerative colitis].
Topics: Colitis, Ulcerative; Gastrointestinal Agents; Humans; Nephritis, Interstitial; Pulmonary Fibrosis; S | 2006 |
7 other studies available for sulfasalazine and Interstitial Nephritis
| Article | Year |
|---|---|
Renal effects of long-term treatment with 5-aminosalicylic acid.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcera | 2009 |
A case of sulphasalazine-induced DRESS syndrome with delayed acute interstitial nephritis.
Topics: Acute Disease; Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Eruption | 2009 |
Reversal of refractory sulfasalazine-related renal failure after treatment with corticosteroids.
Topics: Acute Disease; Colitis, Ulcerative; Gastrointestinal Agents; Glucocorticoids; Humans; Male; Methylpr | 2010 |
Sulphasalazine and mesalazine: serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Inju | 2002 |
How safe are the safest IBD drugs?
Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal A | 2003 |
Sulfasalazine reduces inflammatory renal injury in unilateral ureteral obstruction.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalase; Female; Fibrosis; Free Radical Scavenger | 2007 |
Nephronophthisis and ulcerative colitis in siblings: a new association.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Chronic Dise | 2001 |