sulfasalazine has been researched along with Infarction, Middle Cerebral Artery in 1 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neu2000 protected against the effects of middle cerebral artery occlusion, even when delivered 8 h after reperfusion." | 1.34 | Marked prevention of ischemic brain injury by Neu2000, an NMDA antagonist and antioxidant derived from aspirin and sulfasalazine. ( Ahn, YM; Byun, HY; Cho, JY; Cho, SI; Chung, JM; Gwag, BJ; Im, DS; Kim, KW; Ko, SY; Kwon, HJ; Lee, HU; Lee, JY; Lee, MJ; Lee, YA; Lim, HR; Moon, HS; Noh, JH; Park, SM; Son, SJ; Won, SJ; Yoon, SH; Yun, BS, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gwag, BJ | 1 |
| Lee, YA | 1 |
| Ko, SY | 1 |
| Lee, MJ | 1 |
| Im, DS | 1 |
| Yun, BS | 1 |
| Lim, HR | 1 |
| Park, SM | 1 |
| Byun, HY | 1 |
| Son, SJ | 1 |
| Kwon, HJ | 1 |
| Lee, JY | 1 |
| Cho, JY | 1 |
| Won, SJ | 1 |
| Kim, KW | 1 |
| Ahn, YM | 1 |
| Moon, HS | 1 |
| Lee, HU | 1 |
| Yoon, SH | 1 |
| Noh, JH | 1 |
| Chung, JM | 1 |
| Cho, SI | 1 |
1 other study available for sulfasalazine and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Marked prevention of ischemic brain injury by Neu2000, an NMDA antagonist and antioxidant derived from aspirin and sulfasalazine.
Topics: Animals; Antioxidants; Aspirin; Benzoates; Brain Ischemia; Cells, Cultured; Excitatory Amino Acid An | 2007 |