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sulfasalazine and Ileitis

sulfasalazine has been researched along with Ileitis in 18 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Ileitis: Inflammation of any segment of the ILEUM and the ILEOCECAL VALVE.

Research Excerpts

ExcerptRelevanceReference
" In acetic acid-induced colitis in the rat, levels of malondialdehyde were found to be more markedly reduced with MED15 than with 5-aminosalicylic acid."3.72Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug. ( Belogi, L; Bettelli, E; Mezzadri, CM; Tubaro, E, 2003)
"The effects of 5-aminosalicylic acid (5-ASA), 4-ASA, N-acetyl-5-ASA, and sulfapyridine on mucosal permeability were determined in an experimental model of acute ileitis."3.67Sulfasalazine metabolites and dapsone attenuate formyl-methionyl-leucyl-phenylalanine-induced mucosal injury in rat ileum. ( Granger, DN; Grisham, MB; von Ritter, C, 1989)
" We compare the natural course of amyloidosis complicating Crohn's disease with these complicating familial Mediterranean fever (FMF), and discuss the role of resection and the rationale behind colchicine therapy."3.67Crohn's ileitis complicated by amyloidosis: observations and therapeutic considerations. ( Bass, D; Becker, SA; Nissim, F, 1985)
"Crohn's disease is a perplexing panintestinal disease whose etiology is unknown."2.38Crohn's disease of the small bowel. ( Fazio, VW; Hyman, NH, 1991)
"It is important to distinguish between ulcerative colitis and Crohn's colitis because response to treatment and prognosis are different."2.35Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis. ( Ament, ME, 1975)
"Crohn's recurrence is the appearance of objective signs--defined radiologically, endoscopically or pathologically--of Crohn's disease in the bowel of a patient who has previously had a resection of all macroscopically diseased tissue."1.29Recurrence of Crohn's disease in the neoterminal ileum after ileal resection: is prevention therapy possible? ( Rutgeerts, P, 1994)
"Nine months later she developed angioimmunoblastic lymphadenopathy and was found to have intestinal villous atrophy."1.27Angioimmunoblastic lymphadenopathy, sulphasalazine exposure and villous atrophy. ( Smith, MA; Steele, PR; Youngs, GR, 1985)
"Causal therapy of Crohn's disease up to now cannot be achieved due to the unknown etiology."1.26[Differentiated therapy in Crohn's disease]. ( Riemann, JF, 1981)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199013 (72.22)18.7374
1990's3 (16.67)18.2507
2000's2 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tubaro, E1
Belogi, L1
Mezzadri, CM1
Bettelli, E1
HOFFMAN, FG1
Adebayo, D1
Popat, R1
Thjodleifsson, B1
Bjarnason, I1
Collen, MJ1
Riemann, JF1
Bechi, P1
Briganti, S1
Borsotti, M1
Orsucci, S1
Masi, C1
Fazi, M1
Tonelli, P1
Pratesi, C1
Kirsner, JB1
Deutsch, S1
Hanauer, SB1
Mielants, H1
Veys, EM1
Cuvelier, C1
De Vos, M1
Verbraeken, H1
Ryckaert, S1
Demets, W1
Rutgeerts, P1
Goldstein, F1
Abramson, J1
Messori, DA1
Szydlowski, T1
Thornton, JJ1
Ament, ME1
Hyman, NH1
Fazio, VW1
Ecker, KW1
Güremen, A1
Feifel, G1
von Ritter, C1
Grisham, MB1
Granger, DN1
Smith, MA1
Steele, PR1
Youngs, GR1
Becker, SA1
Bass, D1
Nissim, F1
Pironi, L1
Cornia, GL1
Ursitti, MA1
Dallasta, MA1
Miniero, R1
Fasano, F1
Miglioli, M1
Barbara, L1

Reviews

2 reviews available for sulfasalazine and Ileitis

ArticleYear
Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis.
    The Journal of pediatrics, 1975, Volume: 86, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Anus Diseases; Arthritis; Azathioprine; Child, Preschool; Colectomy;

1975
Crohn's disease of the small bowel.
    Comprehensive therapy, 1991, Volume: 17, Issue:4

    Topics: Anti-Inflammatory Agents; Crohn Disease; Duodenitis; Humans; Ileitis; Intestinal Obstruction; Steroi

1991

Other Studies

16 other studies available for sulfasalazine and Ileitis

ArticleYear
Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug.
    European journal of pharmacology, 2003, Apr-25, Volume: 467, Issue:1-3

    Topics: Acetic Acid; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon;

2003
Regional ileitis (cicatrizing enteritis, Crohn's disease). Some considerations in its medical management and a note on the use of salazopyrine (azopyrin).
    Medical bulletin. United States. Army. European Command. Medical Division, 1950, Volume: 7, Issue:12

    Topics: Crohn Disease; Drug Combinations; Glucosamine; Humans; Ileitis; Sulfasalazine

1950
Granulomatous ileitis in a patient with ankylosing spondylitis.
    Nature clinical practice. Gastroenterology & hepatology, 2007, Volume: 4, Issue:6

    Topics: Adult; Back Pain; Biopsy; Crohn Disease; Diagnosis, Differential; Gastrointestinal Agents; Humans; I

2007
Azulfidine-induced oligospermia.
    The American journal of gastroenterology, 1980, Volume: 74, Issue:5

    Topics: Adult; Crohn Disease; Humans; Ileitis; Male; Oligospermia; Spermatozoa; Sulfasalazine

1980
[Differentiated therapy in Crohn's disease].
    Fortschritte der Medizin, 1981, Feb-05, Volume: 99, Issue:5

    Topics: Adrenocorticotropic Hormone; Crohn Disease; Humans; Ileitis; Peritonitis; Sulfasalazine

1981
Folate deficiency in operated terminal ileitis (Crohn's disease).
    The Italian journal of surgical sciences, 1983, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Crohn Disease; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Hum

1983
Selected individual therapeutic problems in inflammatory bowel disease.
    The American journal of gastroenterology, 1984, Volume: 79, Issue:5

    Topics: Adult; Azathioprine; Campylobacter Infections; Clostridium Infections; Colectomy; Colitis, Ulcerativ

1984
Macroscopic and histological changes of the ileum HLA-B27 related diseases: therapeutic consequences.
    International journal of clinical pharmacology research, 1984, Volume: 4, Issue:6

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Child; Colonoscopy; HLA Antigens; HLA-B27 Antigen; Huma

1984
Pseudotumor of the orbit and Crohn's disease.
    Bulletin de la Societe belge d'ophtalmologie, 1984, Volume: 210

    Topics: Adult; Crohn Disease; Drug Combinations; Female; Fibroma; Glucosamine; Humans; Ileitis; Orbital Neop

1984
Recurrence of Crohn's disease in the neoterminal ileum after ileal resection: is prevention therapy possible?
    The Netherlands journal of medicine, 1994, Volume: 45, Issue:2

    Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Crohn Disease; Humans; Ileitis; Mesalamine; Recurren

1994
Diagnosis and treatment of diffuse ileojejunitis.
    The American journal of gastroenterology, 1977, Volume: 68, Issue:5

    Topics: Adolescent; Adult; Enteritis; Female; Humans; Ileitis; Jejunum; Male; Middle Aged; Prednisone; Radio

1977
[Changes in cell-mediated immune reactions in Crohn's disease].
    Zeitschrift fur Gastroenterologie, 1991, Volume: 29, Issue:10

    Topics: Adult; Colitis; Crohn Disease; Drug Therapy, Combination; Female; Humans; Ileitis; Immunity, Cellula

1991
Sulfasalazine metabolites and dapsone attenuate formyl-methionyl-leucyl-phenylalanine-induced mucosal injury in rat ileum.
    Gastroenterology, 1989, Volume: 96, Issue:3

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Dapsone; Ileitis; Intestinal Absorption; Intesti

1989
Angioimmunoblastic lymphadenopathy, sulphasalazine exposure and villous atrophy.
    Postgraduate medical journal, 1985, Volume: 61, Issue:714

    Topics: Aged; Atrophy; Duodenum; Female; Glutens; Humans; Ileitis; Immunoblastic Lymphadenopathy; Microvilli

1985
Crohn's ileitis complicated by amyloidosis: observations and therapeutic considerations.
    Journal of clinical gastroenterology, 1985, Volume: 7, Issue:4

    Topics: Adult; Amyloidosis; Biopsy; Colchicine; Crohn Disease; Diagnosis, Differential; Familial Mediterrane

1985
Evaluation of oral administration of folic and folinic acid to prevent folate deficiency in patients with inflammatory bowel disease treated with salicylazosulfapyridine.
    International journal of clinical pharmacology research, 1988, Volume: 8, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Colitis; Female; Folic Acid; Folic Acid Deficiency; Humans;

1988